Dempsey: Bartonella is a stealth multi-systemic infection transmitted by fleas, biting flies, body louse, mosquitoes and possibly ticks #ILADS2022 ImageImage
2/Dempsey: Objective findings of #Bartonella include fever, rash, swollen lymph nodes, uveitis #ILADS2022 Image
3/Dempsey: #Bartonella is multisystemic and can involve every organ. #ILADS2022 Image
4/Dempsey: #Bartonella can impact the eyes (#uveitis) heart (#pericarditis #myocarditis), joints, vascular system, brain and more #ILADS2022 Image
6/Dempsey: Molecular testing for #Bartonella will be the best option in the future. Serology tests may miss strains not tested for; PCR currently lacks sensitivity (qPCR is better). #ILADS2022 ImageImageImage
7/Dempsey: #Bartonella is an intracellular pathogen may be widely distributed within tissues. Oral antibiotics work, intravenous therapy not usually needed #ILADS2022
8/Dempsey: Antibiotics are bacteriostatic, not bactericidal: it takes time for the immune system to clear #Bartonella infection. Slow replication cycle, biofilms and tissue cysts may play a role in persistence of infection #ILADS2022
9/Dempsey: Recent practice patterns emerging: Azithromycin or Clarithromycin in combination with Rifampin for #Bartonella treatment. However, beware of drug effects on CYP systems and metabolism of sterol hormones (cortisol, others) when using Clarithromycin / Rifampin #ILADS2022
10/Dempsey: Botanicals such as J. nigra, C. sanguinolenta, and P. cuspidatum have been shown do be effective against stationary phase #Bartonella henselae in vitro. Methylene blue is also showing promise #ILADS2022
11/Dempsey: Ongoing recruiting for #Bartonella tissue study #ILADS2022 Image

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with ILADS/International Lyme & Assoc. Diseases Society

ILADS/International Lyme & Assoc. Diseases Society Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @ilads_lyme

Sep 22
Samuel Shor, MD - Treating Lyme & Chronic Lyme
ILADS defines #chronicLymedisease (CLD) as a multisystem illness with a wide range of symptoms and/or signs that are either continuously or intermittently present for a minimum of six months #ILADS2022 Image
2/Shor:
Only 18% of 1770 children with #Lyme disease
remember being bitten
Nigrovic LE, et al A minority of children diagnosed with Lyme disease recall a preceding tick bite 2019, Vol.10(3), p.694 #ILADS2022
3/Shor: The CDC acknowledges that its #Lyme case definition was developed for surveillance purposes. It is NOT to be used as an absolute criteria for clinical diagnosis. #ILADS2022
Read 4 tweets
Sep 22
Joseph Burrascano, MD - Diagnostic Tools
#Lyme Clinical Presentation: nonspecific, viral-like symptoms that persist, & new ones appear. Then symptoms more focused on musculoskeletal, peripheral and central nervous systems, heart and skin. Muti-systemic & migratory. #ILADS2022 Image
2/Burrascano: Sorting out the co-infections #NotJustLyme #Bartonella #Babesia #Ehrlichia #Anaplasma #Mycoplasma #ILADS2022 ImageImageImageImage
3/Burrascano: Types of tests
SEROLOGIES are indirect, B-cell based tests:
B-cells create antibodies and serologies measure these antibodies #ILADS2022
Read 19 tweets
Sep 22
Robert Bransfield, MD: Thousands of peer-reviewed journal articles demonstrate the causal association between infections and #mentalillness 400+ peer reviewed scientific articles demonstrate the causal association between tick-borne disease and mental illness. #ILADS2022 #Lyme Image
2/Bransfield: Up to 40% of patients w/ #Lyme develop peripheral or central nervous system involvement. Psychiatric reactions include: #paranoia #dementia #schizophrenia #bipolar #panicattacks #depression #anorexianervosa, and #ODC #ILADS2022
3/Bransfield: Lyme is over represented in psychiatric patients. #ILADS2022 Image
Read 15 tweets
Sep 22
Joseph Burrascano, Jr. MD: Ticks are "Nature’s Dirty Needle." In addition to #Lyme, ticks may be infected with #Babesia #Bartonella #Ehrlichia #Anaplasma #Chlamydia #Mycoplasma #WestNileVirus #Nematodes #candida and viruses. #ILADS2022 ImageImage
2/Burrascano: B. microti and B. duncani (also known as WA-1) are the predominant cause of Babesiosis in the United States #Babesiosis has been detected in all 50 states #ILADS2022 Image
3/Burrascano: #Babesia odocoilei has been found in ticks across N America, but not human samples, perhaps due to defective primers. Immunoblot data shows significant % of Babesia species in human patients are not microti or duncani. Could be divergens and/or odocoilei? #ILADS2022
Read 8 tweets
Sep 22
Amy Offutt, MD: Rickettsial & Related Diseases
#RMSF Rocky Mountain Spotted Fever
#Ehrlichiosis
#Anaplasmosis
#Qfever
#Scrubtyphus
#ILADS2022 ImageImage
2/Offutt Ticks are the primary vectors for spotted fevers; some species may be spread by fleas and mites #ILADS2022 #RMSF #Richettsia
3/Offutt: #RMSF is the most severe rickettsial illness in the US with risk of death. Early treatment with #doxycycline is critical, regardless of age #ILADS2022 Image
Read 10 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us on Twitter!

:(