Thread by @RajlabN

#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (15-DAY TRENDS):

16.1% BQ.1.1
13.8% XBB.1.5👀⬆️
11.3% BQ.1
6.4% BQ.1.22
4.3% XBB.1
2.2% BQ.1.1.4
2.0% BQ.1.1.3
1.9% BQ.1.2
1.9% BQ.1.3

Tracker: tinyurl.com/mryj4uu7

#OmicronUpdates 12/24/22
1/n

Sequence count by US State

New York has submitted a huge share of sequences with specimen collection dates in the last 15 days.

2/n

Granular details -#VariantDashboard #USA #15DayTrends

3/n

.@CDCgov updated variant proportions estimates on 12/23/2022 (CDC updates nowcast estimates every Friday)

Several BQ* are circulating at >1% & XBB.1.5* are good candidates to be included in CDC's Nowcast estimates next week!

https://twitter.com/RajlabN/status/1606353523683348480

4/n

The Great Convergence!

Tracked #VariantSoup with key #Spike mutations @ 346, 356, 444-446, 450, 452, 460, 486, 490, 493-494 positions

public.tableau.com/app/profile/ra…

5/n

Predicted Immune Escape and ACE2 binding of top lineages in USA (relative to BA.2)

Bivalent boosters (OG/Omicron.BA.5) will potentially protect the boosted from getting severe disease/hospitalizations.

Please get #boosted ASAP!

public.tableau.com/app/profile/ra…

6/n

#Hospital #Capacity - (by State/Division)

All hospitalizations not just COVID-19

public.tableau.com/app/profile/ra…

7/n

#COVID19 #Hospitalizations in the #UnitedStates

Please get #boosted (especially > 50 yr old and immune compromised) and #MaskUP!

Hospital Tracker (by States, by age group): public.tableau.com/app/profile/ra…

8/n

Status of the latest #COVID19 Wave in #NewYork #BellwetherState

XBB.1.5 is the top circulating lineage in NY

Top Lineages (#15DAYTrends):

XBB.1.5 (35.5%)👀🚀
BQ.1.1 (14.5%)
XBB.1 (9.1%)
BQ.1 (8.1%)
BQ.1.1.3 (2.4%)
BQ.1.11 (2.0%)
BQ.1.1.4 (1.9%)
BQ.1.14 (1.7%)

9/n

Rise of highly immune evasive XBB* family of lineages especially XBB.1.5 (Key mutation: Spike F486P) in NY is concerning

fortune.com/well/2022/11/0…

10/n

BQ* Hotspots - #USA #15DayTrends

11/n

Recombinant lineage hotspots - #USA #15DayTrends

12/n

Tracking the current #COVID19 wave, variant soup and #Hospitalizations in #California

BQ.1 and BQ.1.22 are the top circulating lineage in CA

13/n

A closer look at BQ.1.22....one of the top circulating lineages in #California

As of now, XBB.1.5 and BQ.1.1* are still the top dogs!

14/n

Tracking the current #COVID19 wave, variant soup and #Hospitalizations in #Massachusetts

XBB.1.5 is the top circulating lineage in MA

15/n

Tracking the current #COVID19 wave, variant soup and #Hospitalizations in #Connecticut

XBB.1.5 is the top circulating lineage in CT

16/n

Tracking the current #COVID19 wave, variant soup and #Hospitalizations in #NewJersey

XBB.1.5 is the top circulating lineage in NJ

17/n