Raj Rajnarayanan Profile picture
Feb 3, 2023 β€’ 15 tweets β€’ 16 min read β€’ Read on X
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (#15DAYTRENDS):

48.0% XBB.1.5β¬†οΈπŸ‘€
14.2% BQ.1.1
5.5% XBB.1
4.1% BQ.1
1.4% BQ.1.1.4
1.4% CH.1.1
1.2% BQ.1.3
1.1% BQ.1.1.5

Tracker: tinyurl.com/mryj4uu7
Updated: 02/02/2023

1/n
Sequence count by US State

#California, #NorthCarolina, #NewYork, #NewJersey and #Massachusetts have submitted a big share of sequences

XBB.1.5 stays strong at the top spot and is establishing a clear foot print outside NE USA!

2/n
USA Airport surveillance update #15DayTrends

125 sequences from 6 US States (#California, #NewYork, #Washington, #NewJersey, #Georgia and #Virginia)

A good amount of XBB.1.5 detected via airport surveillance

3/n
Granular details -#VariantDashboard #USA #15DayTrends

XBB.1.5 is surging ahead, leaving the rest of the swarm behind!

4/n
.@CDCgov updated variant proportions estimates on 01/27/2023 (updated every Friday)

CH.1.1 makes an entry @ 1.5% in the CDC Variant Dashboard

XBB.1.5 is leading at the top!



5/n
Top circulating #SARSCOV2 lineages around the world 01/12 to 02/02/23 (#20DayTrends):

BQ.1.1 (18.9%)
XBB.1.5 (18.7%)πŸ‘€^
CH.1.1 (5.3%)πŸ‘€
BQ.1 (3.7%)
XBB.1 (2.7%)
BA.5.2.48 (2.3%)
XBF (1.7%)



6/n
Predicted Immune Escape and ACE2 binding of top lineages in USA (relative to BA.2)

Bivalent boosters (OG/Omicron.BA.5) will potentially protect the boosted from getting severe disease/hospitalizations.

Please get #boosted ASAP!

public.tableau.com/app/profile/ra…

7/n
#Hospital #Capacity - (by State/Division)

All hospitalizations not just COVID-19

public.tableau.com/app/profile/ra…

8/n
#COVID19 #Hospitalizations in the #UnitedStates

Please get #boosted (especially > 50 yr old and immune compromised) and #MaskUP!

Hospital Tracker (by States, by age group): public.tableau.com/app/profile/ra…

9/n
Status of the latest #COVID19 Wave in #NewYork

XBB.1.5 is still the top circulating lineage in NY

10/n
Circulating recombinant lineages - USA #15DayTrends

XBB.1.5 is still the top recombinant in circulation!

11/n
Tracking circulating #SARSCoV2 lineages, Cases, #COVID19 #hospitalizations πŸ‘€ in #California

XBB.1.5 is the top circulating lineage in CA

Top circulating lineages

XBB.1.5 (25.1%)πŸ‘€
BQ.1.1 (16.4%)
XBB.1 (7.0%)
BQ.1.1.32 (4.6%)
BQ.1.28 (4.1%)
BQ.1 (3.6%)

12/n
Tracking circulating #SARSCoV2 lineages, Cases, #COVID19 #hospitalizations in #Arizona

XBB.1.5 is the top circulating lineage in AZ

[low sequence count]

13/n
Tracking circulating #SARSCoV2 lineages, Cases, #COVID19 #hospitalizations in #Texas

XBB.1.5 is the top circulating lineage in TX

14/n
Tracking circulating #SARSCoV2 lineages, Cases, #COVID19 #hospitalizations in #NorthCarolina

XBB.1.5 is the top circulating lineage in NC

15/n

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More from @RajlabN

Aug 11
Tracking #SARSCoV2 #Lineages - Globally |08/10/24

Top lineages -#30DayTrends

KP.3.1.1 (24.2%)πŸ‘€
KP.2.3 (9.5%)
KP.3.3 (8.4%)
KP.3.1 (5.9%)
LB.1 (2.5%)
KP.2.2 (2.4%)
KP.2 (2.4%)
KP.3 (2.3%)
LB.1.7 (2.3%)
KP.3.2.3 (2.2%)

Track #G30 :

1/n public.tableau.com/app/profile/ra…
Image
Granular details #Global #30DayTrends

KP.3.1.1 is the top circulating lineage in the world. This analysis includes #SARSCoV2 sequences submitted to @GISAID with sample collection dates on or after 07/11/2024 (15,325 sequences)

2/n Image
@GISAID Thanks to all the countries that are still supporting #SARSCoV2 testing and rapidly submitting sequences to @GISAID

Top submitters: #USA #Canada #UK #Japan #Spain
#France #China #Netherlands #Israel #Ireland
#Australia #Singapore #Denmark #Italy #Sweden #Germany #Guatemala Image
Read 21 tweets
Jul 28
Tracking #SARSCoV2 #Lineages - Globally |07/27/24

Top lineages -#30DayTrends

KP.3.1.1 (17.4%)πŸ‘€
KP.2.3 (8.1%)
KP.3.3 (8%)
KP.3.1 (7.2%)
KP.3 (3.3%)
KP.2 (3.1%)
KP.3.1.4 (3.1%)
KP.3.2 (3%)
LB.1 (2.5%)
KP.3.2.3 (2.5%)

Track #G30 :

1/n public.tableau.com/app/profile/ra…
Image
Granular details #Global #30DayTrends KP.3* is the dominant group of lineages in the world.

This analysis includes #SARSCoV2 sequences submitted to @GISAID with sample collection dates on or after 06/27/2024 (12,753 sequences)

2/n Image
Thanks to all the countries that are still supporting #SARSCoV2 testing and rapidly submitting sequences to @GISAID

Top submitters: #USA #UK #Canada #Spain #Japan #Israel #Australia #Ireland #France #Denmark #Singapore #NewZealand #Germany #Netherlands #Sweden #Taiwan

3/n Image
Read 15 tweets
Jul 26
#H5N1 Updates #AvianInfluenza

@USDA #APHIS #NVSL has submitted 211 sequences on 7/24/24 with collection dates in 01 to 06/2024

12 #cow milk seqs from #Minnesota with **PB2 Q591R** in addition to the cattle outbreak signature M631L [isolate ID 24-016288-001 to 015!]

1/n Image
PB2 Q591R: A basic amino acid at position 591 of PB2 can compensate for the lack of lysine at position 627 and confers efficient viral replication to pandemic H1N1 viruses in mammals.

ie., Q591R ~ E627K! πŸ‘€



2/n pubmed.ncbi.nlm.nih.gov/20700447/
Image
Some of the seqs are already in the tableau mutational profile of WGS data from USDA-NVSL

as highlighted by @0bFuSc8



3/n
Image
Read 6 tweets
Jul 20
Tracking #SARSCoV2 #Lineages - Globally |07/20/24

Top lineages -#30DayTrends

KP.3.1.1 (14.2%)πŸ‘€
KP.2.3 (7.9%)
KP.3.1 (7.8%)
KP.3.3 (7.7%)
KP.3.2 (3.8%)
KP.3 (3.4%)
KP.3.1.4 (3.4%)
KP.2 (3.4%)
LB.1 (2.7%)
KP.2.2 (2.7%)

Track #G30 :

1/n public.tableau.com/app/profile/ra…
Image
Granular details #Global #30DayTrends KP.3* & KP.2* are the dominant group of lineages in the world.

This analysis includes #SARSCoV2 sequences submitted to @GISAID with sample collection dates on or after 06/20/2024 (12,854 sequences)

2/n Image
@GISAID Thanks to all the countries that are still supporting #SARSCoV2 testing and rapidly submitting sequences to @GISAID

Top submitters: #USA #UK #Canada #Spain #Japan #Israel #France #Singapore #Netherlands #Australia #Ireland #Iceland #China #Sweden #Portugal #Italy

3/n Image
Read 19 tweets
Jun 19
#COVID19 #VariantDashboard - #USA | 06/18/24
#SARSCoV2 #Lineages #30DAYTRENDS

KP.2.3 (7.7%)
KP.2 (7.4%)
KP.3.1 (5%)
KP.3.3 (4.8%)
JN.1.16.1 (4.2%)
LB.1.7 (4%)
JN.1.16 (3.4%)
KP.1.1.1 (3.4%)
LB.1.3 (3.3%)
KP.2.2 (3.1%)
--
KP.3.1.1 (1.5%)πŸ‘€


1/ntinyurl.com/mryj4uu7
You can filter spike mutations S31del, R346T, L455S, F456L, T572I (Top convergent mutations) to display #SLip, #FLiRT, #TiRT, #FLiRTTI, #DeFLiRT combo mutations; (Note: retired #FLip as of now)

Also, by state, lineage, collection date

2/n Image
#AirportSurveillance data - @CDCgov

Traveler Based Genomic Surveillance Program ( )

New: included "Travel history: Mediterranean Norwegian escape" use sampling strategy menu to display (a KP.5 and KP.2 is reported from WY)

3/n wwwnc.cdc.gov/travel/page/tr…
Image
Read 7 tweets
Jun 9
Tracking #SARSCoV2 #Lineages - Globally |06/08/24

Top lineages -#30DayTrends (#G30)

KP.2.3 (8.7%)
KP.2 (8.7%)
KP.3.1 (7.7%)
KP.3 (6.2%)
KP.3.2 (5.1%)
LB.1 (5%)
KP.1.1 (4.9%)

Track:

1/n public.tableau.com/app/profile/ra…
Image
Granular details #Global #30DayTrends

KP.3* & KP.2* are the dominant group of lineages in the world.

This analysis includes #SARSCoV2 sequences submitted to @GISAID with sample collection dates on or after 05/09/2024 (8,025 sequences)

2/n Image
@GISAID You can filter spike mutations S31del, R346T, L455S, F456L, T572I (Top convergent mutations) to display #SLip, #FLiRT, #TiRT, #FLiRTTI, #DeFLiRT combo mutations; (Note: retired #FLip as of now)

4/n Image
Read 15 tweets

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