In Oct 2021, I had a routine blood test that revealed elevated liver enzymes. A later blood test with a different doctor showed the liver panel was "elevated and worsening", more than double the normal range for some variables. 2/5
A series of additional tests, including abdominal ultrasound, were negative. Physician referred me to a gastroenterologist who suggested (an invasive) liver biopsy. However, before the next blood test, I stopped exercising for 7 days. 3/5
Values basically normalized, suggesting the elevated "liver panel" was the result of exercise-induced muscle damage and/or increased hepatocyte membrane permeability. Remember, ALT and AST have an important role in Krebs, not just in "liver function" 4/5
Importantly, none of the doctors assessed muscle function (e.g., CK) or enquired about my exercise training habits. "Such omissions in the diagnostic pathway can result in the misdiagnosis of liver problems and unnecessary follow‑up tests and referrals." 5/5
END.
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First and foremost, you can read here the full EIC retraction notice: ♾doi.org/10.1123/ijsnem…
♾And my "Letter to The Editor" in which I describe in more detail the most serious/perplexing issues: tinyurl.com/2p8f5mj7
🧵2/13
I learned about this study after Dr. Rhonda Patrick (Ph.D. in biomedical science) shared it among her nearly 400,000 Twitter followers who, in turn, retweeted it more than 500 times. 🧵3/13
I was asked recently to provide some examples of health and fitness marketing that makes false claims and/or exploits human biases. I came up with a billion examples. Here are just 6:
The official #Olympics website endorsing #cryotherapy as an effective form of post-exercise recovery. Despite the fact the literature is very unimpressive, littered with low-quality studies, and tiny effects. #IOC