Discover and read the best of Twitter Threads about #liver

Most recents (24)

The U.S. CDC has issued a nationwide alert for medical professionals to report any cases of #hepatitis in #children. The alert was made after a cluster of 9 severe hepatitis cases was identified in children aged 1-6 in Alabama. #CDC #CGTNAmerica Image
In Alabama, several children developed liver failure and two had to receive liver transplants. #hepatitis #children #CGTNAmerica
Severe #hepatitis cases among children were also found in Denmark, Ireland, the Netherlands, and Spain after a report last week in the U.K. that found 74 cases in #children since January. #CGTNAmerica
Read 4 tweets
🧵 In the US, until recently, your chances of receiving a donated #liver w/in 30 days would vary significantly depending on where you lived—as low as 1%, or as high as 60%. Remember Steve Jobs' speedy liver transplant? He got on multiple waitlists...🧵 columbiasurgery.org/news/end-liver…
For decades, experts and providers have been pressing for a more equitable system of organ allocation, one that would even the odds between, say, a patient in a dense urban center with a long waitlist and a patient in a more rural, statistically healthier area with a short one.
For almost 50 years, the system in place was an outgrowth of informal sharing networks between doctors and medical centers, resulting in a web of organ procurement organizations (OPOs) and donation service areas (DSAs) spread out across the country. #donatelife
@UNOSNews
Read 8 tweets
@DrHachi3 “New Anti-#HIV Triterpene from Geum japonicum“

cpb.pharm.or.jp/cpb/200009/C09… ImageImage
@DrHachi3 Patent - A pharmaceutical composition including an extract from Geum japonicum and a method of treating cancer using the extract. The extract can induce selectively apoptosis of cancer cells and kill the cancer cells without affect normal cells.“

patents.google.com/patent/US20090… ImageImage
@DrHachi3 “The Antiapoptosis Effect of Geum japonicum Thunb. var. chinense Extracts on Cerebral Ischemia Reperfusion Injury via PI3K/Akt Pathway”

#stroke

hindawi.com/journals/ecam/… Image
Read 5 tweets
Hey Twitter! It's been a while. I used to write here all the time hanging out with #scifichat, #comicschat, #litchat, talking about #science, #tech, #autism and a dozen other topics which broadened my horizons and let me share my diverse interests in almost everything.
Then my life got incredibly busy. My son went to high school and coupled with his #autism, our lives became super-complex. I lost my job and my car gave up the ghost after four years of @Uber. Then the unthinkable, my wife experienced #renalfailure.
4 years ago, she underwent an operation for #peritoneal #dialysis. This form of at-home dialysis would let her take care of her renal needs at home avoiding the need for external #hemodialysis centers. In hindsight, this may have saved her life.

texastribune.org/2021/03/30/pan…
Read 26 tweets
Image
Early recognition of cirrhosis is important Image
Read 26 tweets
Some cases!
Two flavors of DILI

🔺Intrinsic: intrinsically hepatotoxic (e.g., acetamionophen)

🔻Idiosyncratic: unpredictable ❔
Read 16 tweets
A case!
⚠️11% of patients with incidentally discovered steatosis may be at risk for advanced hepatic fibrosis!
Read 16 tweets
1/🧵🎥 MAJOR TIPS about #Liver Disease
 
Why do we ask pts to “hold up traffic”? When people get severe liver disease, “asterixis” is a finding on exam we often see.

What does it mean?
 
#MedTwitter #NurseTwitter #TipsforNewDocs #Addiction
2/ Asterixis indicates that toxins like ammonia have built up in the body because the scarred liver no longer filters them out. The brain cells no long function normally (#Delirium or Hepatic #Encephalopathy) & can no longer control muscle movements like posture!
3/ These same toxin cause vessels to dilate and develop problems with blood flow in the skin and lungs. A skin finding is called “spiders.” They look like a multi-legged spider, right? It’s a tip-off.
Read 9 tweets
ICYMI, a reminder that this pandemic will have a lasting legacy beyond the tragedy of the countless lost lives and grieving families. Results from the #COVERSCAN study on #longcovid reports that organ impairment was detected in post COVID patients as shown in the figure below
This included damage to the #heart, #lungs, #kidneys, #liver, #pancreas and #spleen In almost a third of patients, damage in 2 or more organs was identified. In particular, damage to the liver, heart or lungs was associated with further organ impairment.
The participants in this study were all considered to be previously at low risk of #mortality and had no #comorbidities. bmjopen.bmj.com/content/11/3/e…
Read 6 tweets
#WorldLiverDay 🎗️ #Liver
కాలేయం మానవుని శరీరంలో చర్మం తర్వాతి రెండవ అతి పెద్ద అవయవం(గ్రంథి) కాలేయమే! దాదాపు 1,500 గ్రాముల బరువుండే కాలేయం పని తీరు కూడా భారీగానే ఉంటుంది. ఇది ఉదరంలో ఉదరవితానానికి (డయాఫ్రమ) క్రిందగా కుడివైపున మధ్యలో ఉంటుంది. కాలేయము పైత్యరసాన్ని తయారుచేస్తుంది.
అది పిత్తాశయంలో నిలువచేయబడి జీర్ణక్రియలో చాలా తోడ్పడుతుంది. పైత్యరసవాహిక ద్వారా పైత్యరసము, ఆంత్రమూలానికి చేరుతుంది.

కాలేయము, ఆంత్రమూలానికి కుడి పక్కన ఉదరవితానానికి దిగువగా ఉంటుంది. ఇది బూడిద రంగులో ఉంటుంది.కాలేయానికి నాలుగు తమ్మెలుంటాయి. దీనిలోని కణాలను కాలేయకణాలంటారు.
కాలేయం వ్యాధికారక ఇన్‌ఫెక్షన్లతో పోరాడుతుంది. విషాలను హరిస్తుంది, రక్తం గడ్డకట్టడానికి తోడ్పడుతుంది.శరీరం మొత్తంలో పెరిగే గుణం కలిగిన ఒకే ఒక అవయవం ‘కాలేయం’. విషాలను హరించటం మొదలుకుని దాదాపు 500 రకాల జీవక్రియలను నిర్వర్తించే శక్తి కాలేయానికి ఉంది.
Read 15 tweets
Foods in our #diet can alter the pro-inflammatory vs anti-inflammatory milieu of the intestinal #microbiome.

See 🧵 below for the findings!

🥬🍑🍅🍠🥚🍎🧀🍆🫒🫓🍇🥦🥑🥥🥯🌶️🧄🥖

#GITwitter #GI #gut #nutrition

gut.bmj.com/content/early/…
🥖 🥜 🐠 🌰
Breads, legumes, fish and nuts⬇️several pro-inflammatory pathways:
🫓⬇️pathogenic growth factors & endotoxins
🫓⬇️ pathogenic E. coli, Bacteroides fragilis, parabacerioides
🫓⬆️ammonia detoxification pathway
🌰🐟 🍑🥦
Nuts, oily fish, fruit, vegetables & cereals ⬆️short-chain fatty acid producers
🫑⬆️Faecalibacterium prausnitzii, roseburia hominis, and more

Bacteria ferment fiber and pectins to acetate and butyrate.

SCFAs have anti-inflammatory effects on the mucosa!
Read 20 tweets
1
Listen to this story of #tuberculosis
Real, not fiction. Even though may sound like super fiction. Of a patient now admitted under me.

56 yr man. Prior #smoker No #alcohol use, no #DRUGS. Family guy. Starts havin cough. Nagging no sputum
Keeps him awake at night
#MedTwitter
2
He goes 2 a GP. Clinical examination and blood tests done. Says some chest infection. Puts him on antibiotics for a week. Asks for review. 1wk later some change in symptoms, but not fully ok. GP extends antibiotic course 7 more days. C, no fever and no signs of infection yet.
3
After 14d course, no change. Patient chucks the GP. Goes for a senior GP. Senior GP does clinical exam,blood tests AND chest X ray. X ray comes back as "not looking normal" 🙄 But no diagnosis. So he says. Let's try a short course of #antibiotics AND antifungal. Again 14 days
Read 18 tweets
Hi Kiran, Im sorry 4 ur loss. Ur statements R real, not bluff. Thank U 4 sharing ur father's (RIP) report of liver #cancer.

1/ Nw, coming back to ur original statement.
Modern #medicine said dad wil hav 8 mo to survive, but #homeopathy gave him 4 yrs.

2/ Im stil convinced #homeopathy did not work

And I knw Y U felt tat way

I blame UR oncologist - he mayB gud wit diagnosis, but he has no insight & communication skils

I blame ur #homeopath.
He is a quack but gud with communication skills

Want to knw why? Let me xplain👇
3/
Be4 we start, chek this figure from @nature
This shows latest guidelines on treatment of #liver cancer, survival and options.
Luk at stage 0 and stage A [stable #cirrhosis, early disease)
Survival > 10 yr - transplant
Survival > 6 yr - removal surgery, tumor burn (ablation)
Read 11 tweets
I was sent these samples from a #hospital in #Chennai after the #physician caring for a patient wit abnormal #liver test found he was on these for #COVID19
#Coronil by #Patanjali Batch A-CNT305
#Liv52 by #Himalaya Batch 72900775
We performed ICP-OES, GCMSMS analyses
Results👇
1/
Heavy metals
1. Lead
Values higher than prescribed @US_FDA➡️ bit.ly/3miSHBM, #India bit.ly/3oV794F
Lead in drugs unheard of in developed countries. #India is developing (currently underdeveloped), hence an excuse. Lead limit in paints 90mg/kg.
2/
#MedTwitter
Heavy metals
2. Cadmium
C @US_FDA list beneficial & harmful metals in humans ➡️bit.ly/2LDTEbj
Cadmium prolonged use cause multiple organ toxicity sometime wrongly diagnosed
See bit.ly/37iTVZe
Indian herbs R sources of Cd bit.ly/37ZQTIJ
#livertwitter
3/
Read 4 tweets
#Ayurveda treatment for alcoholic #liver #cirrhosis - case based protocol, described in a case series of 3 patients.
Once again, forget @NetflixIndia comedy shows, this is where all the fun, comedy and jokes are now.

Caution: This limited series will drop your IQs
#MedTwitter
1/
Introduction:
🔅#Ayurveda is a philosophy. Correct. No therapeutic value.
🔅Uncertainty due to uncertainty😳 HUH?
🔅#Ayush guys got 'sanskrit' spelling wrong 😵 whats with that?
🔅Time to combine evidence based medicine with case based medicine. What #herb is the author on?
2/
🌿Alcoholic is not correct. Alcohol related/associated. More compassion toward patient. But what does #Ayurveda know abt compassion right? Need a herb 4 that.
🌿Specifically note the sentence bad mouthing scientific, conventional care. That's hw these #ayush #quacks survive.
3/
Read 6 tweets
Important paper 👉 A team in Tokyo took RNA-seq data from the Genomic-#Tissue Expression Project: a public resource created to study tissue-specific gene expression/regulation from 54 tissue types collected from 1000+ healthy individuals at autopsy: bmcbiol.biomedcentral.com/articles/10.11…
2/ They successfully identified 39 viral species in at least one tissue (tissue types included #brain, pituitary, esophagus, thyroid, #heart, breast, lung, kidney, adrenal gland, prostate, #nerve, adipose tissue, blood vessel, ovary, uterus etc)
3/ Viruses identified in the various tissue samples included EBV, HSV-1, Varicella, CMV, HHV6-A/B, HHV-7, HCV, HPV, adeno-associated virus...and 16 RNA #viruses including Respiratory syncytial virus (RSV), Parainfluenza Virus 3..
Read 12 tweets
Our invited expert review on #Ayurvedic #herbals and #liver #toxicity. #herbal #medicine is NOT safe. Review on #herbs used in #Indian #traditional #medicine & adverse events is lacking in #published #Literature
We deep searched, compiled
Full paper: bit.ly/35WkCmr
1/4 Image
This #review is important for #ayush practitioners and those interested in opting for #alternative #therapies as #knowledge regarding potential #toxic components is the #right of every #patient and #moral #duty of the physician. This 👇 list show names of imp toxic herbs.
2/4 Image
We give #real #life #patient data supporting our review: such as this example which shows that #Ayurveda #drugs cause severe #chronic #liver #damage that can lead to #cirrhosis in the short term.
The implicated agent here is Holarrhena antidysenterica (Tellichery bark)
3/4 Image
Read 5 tweets
#livertwitter #GITwitter #MedTwitter #tweetorial
#Cirrhosis, right lobe atrophied, relative hypertrophy of left lobe
📌Splenic/superior mesenteric vein blood flow changes👉distortion of liver structure, re-routing hepatotropic substances to left, less to right➡️ Rt atrophy
1/ Image
❓But in #BuddChiari #Syndrome, caudate lobe enlarged
📌"#laminar flow’ theory"👉 larger redistribution of nutritients,hormones,hepatotropic factors to left hemi-liver at caudate level, most portal branches supplying caudate lobe from left portal vein #MedStudentTwitter
2/ Image
#Fatigue primary biliary cholangitis (#PBC)
📌cholestasis, #endotoxemia, systemic #Inflammation👉dysautonomia, central/peripheral neurovascular dysfunction, sympathetic overactivity, impaired baroreflexes, low peripheral #muscle perfusion, lactic acid mishandling, fatigue
3/
Read 9 tweets
1mo writing, 4mo #PeerReview
Finally! Our invited #publication on #infections in #cirrhosis World Journal of #Hepatology
Update on diagnosis and management of sepsis in cirrhosis
Full paper: bit.ly/32shuv6
Exhaustive discussions, new stuff..1/4
#livertwitter #MedTwitter Image
...a lot of important defining and prognosis powered scoring systems used in #sepsis 2/4
#MedStudentTwitter Image
...biomarkers new and old for sepsis 3/4
#ScienceTwitter #medicine #biomarkers Image
Read 4 tweets
1/3
The devil is in the 'detailed' #drug history #clinical
22 yr male, underweight
Teetotaler
Fatigue, appetite loss
Liver test AST 400 ALT 600
Viruses negative
Liver #biopsy 👇Severe #fatty #liver #disease, Mallory Denk++
#livertwitter #pathology #MedTwitter #MedStudentTwitter Image
2/3
The culprit 👇#Ayurveda #medicine
#Ayurvedic jam with butter, honey, milk as base given for premarital #weight gain! 3 months after stopping, liver tests normal
Consider #drug induced fatty liver in #patients. Not everyone is #metabolic #syndrome
#pseudoscience #Nash #nafld Image
3/3
Common drugs causing fatty liver
Steroids, Valproate
Inj Tetracycline
#HIV #AIDS meds NRTIs
Rare - methotrexate, chemodrugs irinotecan, 5FU, tamoxifen
Also important is Amiodarone
Herbals with #Margosa oil too
Remember #alternative meds rich in fats are important causes too.
Read 3 tweets
So this #Stupidity hits close to home. So a #discussion on #arsenicum album 30.
📌30 means 30 times diluted, standard for #Homeopathy
📌What is #diluted? ➡️ #Arsenic trioxide
📌#homeopath says only 0.443mg of compound per pellet
📌Thats #safety levels right? ➡️ NO.
Read on
2/n
#Arsenic whatever form, concentration, level, is #dangerous #harmful to #humans.
📌Even LOW DOSE intermediate to #long use can lead to #Cancer
📌Actually, many types of #Cancers - #skin, #liver, #bladder, #kidney, #lung
📌Those with #diabetes #heartdisease its #deathwish
👇
3/n
📌NOT one proper #study on this #drug in #Medical #history
📌Read artilce @AltNewsScience debunking fake evidence: bit.ly/2Xra5KY
📌#traditional use was in #diarrhea
📌#pseudoscience at its best
👇 Arsenic is As and not ARS
🔥Even though arsenicum album is #crap
4/n
Read 5 tweets
#Advice - #DONT drink #AloeVera or eat its #extracts
📌Very #liver #toxic, especially #cirrhosis
📌Possibly cause #Cancer
📌Damage #cell #DNA
See: bit.ly/2BXHcyy & bit.ly/31gINb4
👇patient #liverbiopsy - lightpink area all liver cells #DEAD
#livertwitter
1/2 Image
📌Check your #nutrition #supplements
📌Double check #famous #weightloss supplements
📌Aloe-Vera = #Herbal liver injury
📌Some benefit in #skincare #dermatology, nothingelse! bit.ly/33h0rOO
📌Always disclose to your #Doctor
#MedTwitter #MedStudentTwitter #Ayurveda
2/2
Nobody follows this. Whole #plant is mostly used! #plantbased supplemental diets with whole Aloe-Vera for treating conditions like #diabetes and #jaundice leads to #catastrophe
#regulation = 0 in #India. All Aloe Vera treatments by #WhatsApp #Doctors Image
Read 5 tweets
6 THINGS YOU SHOULD KNOW ABOUT HEPATITIS B

1. Affects your liver
2. Extremely infectious
3. Many show no symptoms
4. Vaccine protects you
5. Can be treated
6. You can live a long, productive life with #HepatitisB infection if you treated.

A thread 🧵

{RT for awareness!} Image
First, #HepatitisB, like other viral hepatitis, loves the #liver.

Once infected, the virus goes straight to your liver, multiplies alarmingly, & tries to evade immune attacks.
In some, immune system clears the virus so they recover. In others, no, so they remain infected. Image
People who remain infected with #hepatitisB over a long period of time may develop liver issues.
Such liver problems may include #fibrosis, #cirrhosis, #livercancer, & #liverfailure.
If not detected & treated on time, the person may die of these complications. Image
Read 17 tweets
1/2
2017: #young #male after a #trip to Hills with '#Naturalists'. Fever and abnormal liver tests. #jaundice in a week. Long evaluations multiple places. Following up as fever of unknown origin. Father a pastor. Son denies everything, studious. #Liver #biopsy done.
#livertwitter Image
2/2
Classical #liverpath
Top:Lobular #inflammation, #Portal triaditis; Bottom: central venulitis, perivenular #cholestasis
Asks young man alone, 1hr #interrogation
Finally, S(n)ORTED OUT THE PROBLEM.
#Cocaine induced #Hepatitis
Its pays to invest in good #clinical #history
Read 3 tweets

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