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Apr 25 9 tweets 6 min read Twitter logo Read on Twitter
In this one, a high dose (2.5mg) of phenylcapsaicin was associated with a plausible ergogenic effect on strength performance, muscle damage and peripheral perceived exertion in comparison to a placebo and a lower dose of 0.625mg during resistance training. Image
- The aim of this study was to explore the effects of low dose (0.625 mg) and high dose (2.5mg) of phenylcapsaicin on full squat performance, active muscle and overall body ratings of perceived exertion, muscle damage, protein breakdown, metabolic response, and 24-h recovery.
These assessments were approached under a randomized, triple-blinded, placebo-controlled, crossover design.
- Although 2.5mg of phenylcapsaicin reduced active muscle ratings of perceived exertion and enhanced mechanical performance, it also exhibited lower muscle damage in comparison to placebo and the lower dose.
- The main effects were documented through reductions in maximal velocity loss and eliciting a positive trend in the velocity of the slowest repetitions compared to placebo and the lower dose.
- 2.5mg of phenylcapsaicin was also effective in reducing muscle damage.
- Therefore, the results of this study confirm a plausible ergogenic effect of phenylcapsaicin on strength training and performance, but a high dosage seems to be necessary.
Effects of different phenylcapsaicin doses on resistance training performance, muscle damage, protein breakdown, metabolic response, ratings of perceived exertion, and recovery: a randomized, triple-blinded, placebo-controlled, crossover trial (open access)

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More from @nick_krontiris

Apr 26
The findings of this one suggest that even though exercise may be beneficial for some aspects of children's cognition (information processing speed), those with higher levels of habitual physical activity may also benefit in other aspects too (executive control efficiency).
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Apr 26
This review tries to address the ideal duration and intensity of physical activity, and the types of exercise for optimizing lifelong cardiovascular health, longevity, and healthspan. Image
Summary:
- Physical fitness is the single best predictor of life expectancy and healthspan. Try to achieve and maintain a high level of physical fitness throughout life.
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Apr 26
In this one, obesity, but not overweight, was associated with a higher risk of death from middle to older age, irrespective of the adiposity index used, suggesting that obesity should be prevented across the lifespan, including in individuals up to 85 years of age. Image
- Lower risk of mortality in older participants with overweight compared with normal weight when adiposity was assessed by the fat mass index was observed.
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Apr 25
This one in hyperinsulinemia- and hyperglycemia- prone mice suggests that both endurance and strength training can be effective ways to mitigate the impacts of hyperglycemia and hyperinsulinemia. Image
- In this study, both short-term endurance and strength training protocols controlled the elevated fasting glucose and insulin, leading to improved whole-body insulin sensitivity and glucose tolerance.
- While endurance exercise appeared to play a vital role in transcriptome and mitochondrial activity, strength exercise mainly affected post-translational mechanisms and protein synthesis.
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Apr 25
In this one, females with high levels of physical activity showed a more pronounced flexion-relaxation phenomenon compared to those with moderate and low levels of physical activity, suggesting that high levels of physical activity may lower risk for low back pain. Image
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Apr 25
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