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π Older adults make up 56% of the global cancer population, yet they're just 40% of participants in new cancer therapy trials. The underrepresentation of this key demographic in clinical trials is a major concern. #clinicaltrials #healthcare #aging 
πTrials biased towards younger patients without comorbidities and multiple prescription drugs yield cleaner datasets but may not provide sufficient evidence on drug safety and efficacy for older populations. 2/3
#ClinicalTrials #aging #healthcare
#ClinicalTrials #aging #healthcare
π US and UK regulators recognize the problem and have issued guidelines to address it recently. While guidelines and incentives can make a difference, legislation may be necessary to fully tackle the problem in the end. βοΈ 3/3
#ClinicalTrials #aging #healthcare #FDA
#ClinicalTrials #aging #healthcare #FDA
π Later, I'll write a thread about the importance of gender balance in preclinical animal studies and clinical trials. I'll also discuss how anti-aging treatments can yield different results in animals based on sex. π#ClinicalTrials #healthcare #aging
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