Thread by @RajlabN

#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (#15DAYTRENDS):

60.7% XBB.1.5
7.3% XBB.1.16👀
4.1% XBB.1.9.1
1.3% XBB.1.5.1
1.3% XBB.1.9.2
1.2% XBB.1.5.19
1.1% XBB.1.16.1👀
1.0% XBB.1.5.31

#SARSCoV2 Tracker: tinyurl.com/mryj4uu7 Updated: 04/19/23
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Use "Airport Surveillance" (AS) pull-down menu to easily track variant proportions Nationally or by State with or without AS sequences

Top lineages (#15DayTrends w/o AS seqs):

XBB.1.5 (65.9%),
XBB.1.9.1 (4.2%),
XBB.1.16 (3.4%),⬆️👀
XBB.1.5.19 (1.4%),
XBB.1.5.1 (1.3%)

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Sequence count by US States

#NewYork, #California, #Arizona, #NorthCarolina and #Utah have submitted a big share of sequences with specimen collection dates on or after 04/04/2023

XBB.1.5 is still at the top spot; followed by XBB.1.9.1 and XBB.1.16

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Granular details -#VariantDashboard #USA #15DayTrends

XBB.1.5* (VOI -@WHO) is still ahead of the other lineages!

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.@CDCgov updated variant proportions estimates on 04/14/2023 (updated every Friday)

XBB.1.16, XBB.1.9.2 and FD.2 make an entry!

Prudent to start tracking XBB.1.5.13 (parent of EK.1* and EK.2*) and XBB.2.3* as well


4/n

XBB.1.16 has the potential to outcompete all other circulating lineages.

Everyone is closely watching XBB.1.16 hotspots for clues

Tracker: public.tableau.com/app/profile/ra…… 5/n

XBB.1.16 is one of the fittest variant in circulation right now.. and is picking up additional mutations... "its the one to watch"

H/T @ErinMPrater @WellatFortune
@FortuneMagazine
fortune.com/well/2023/03/3…

6/n

What to know about the XBB.1.16 COVID variant causing concern in India

H/T @ingridhein @medpagetoday
abcnews.go.com/Health/xbb116-…

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Predicted Immune Escape and ACE2 binding of top lineages in USA (relative to BA.2)

Bivalent boosters (OG/Omicron.BA.5) will potentially protect the boosted from getting severe disease/ hospitalizations.

Get updated if you haven't already! public.tableau.com/app/profile/ra…

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.@CDCgov has authorized a second dose of the bivalent Omicron-BA.5 vaccine for older adults and immunocompromised adults to get



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#Hospital #Capacity - (by State/Division)

All hospitalizations not just COVID-19

public.tableau.com/app/profile/ra…

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#COVID19 #Hospitalizations in the #UnitedStates

>60 yr old & immunocompromised Have a good look at @CDCgov info on #Boosters!

#Ventilate Indoor spaces

Sick? --> Wear a good quality #Mask!

Hospital Tracker (by States, by age group): public.tableau.com/app/profile/ra…
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Circulating recombinant lineages - USA #15DayTrends

XBB.1.5 is still the top recombinant in circulation!

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Status of the latest #COVID19 Wave in #NewYork
#Bellwether #State

Top circulating lineages in NY (#15DayTrends)

XBB.1.5 (60.5%)
XBB.1.16 (11.1%)👀
XBB.1.9.1 (5.6%)
XBB.1.19.1 (2.5%)
XBB.1.5.1 (2.5%)
XBB.1 (1.9%)
XBB.1.5.24 (1.9%)
XBB.1.16.1 (1.2%)

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Status of the latest #COVID19 Wave in #California

Top circulating lineages in CA (#15DayTrends)

XBB.1.5 (48.8%)
XBB.1.16 (16.8%)👀
XBB.1.9.1 (4%)
XBB.1.5.33 (3.2%)
XBB.1.5.20 (2.4%)
XBB.1.9.2 (2.4%)
XBB.1.16.1 (1.6%)
EG.1 (1.6%)

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Status of the latest #COVID19 Wave in #Texas

XBB.1.5* is still the top circulating lineage group in TX

[low sequence count]

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USA Airport surveillance update #15DayTrends

195 sequences from 6 US States (#California, #NewYork, #Washington, #NewJersey, #Georgia and #Virginia) from @CDCgov's Traveler-Based Genomic Surveillance Program.

*Includes pooled swabs & Many bad QC seqs

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As COVID Tracking Wanes, Are We Letting Our Guard Down Too Soon?

"Closing up shop too early could mean we are blindsided"

“You have to maintain a base level of sequencing for new variants"

H/T @DohenyKathleen @WebMD
webmd.com/covid/news/202…… 17/n