holy fuckin shit 
context: flumazenil is a competitive inhibitor of GABA-A, which is the receptor that benzodiazepines primarily effect
flumazenil is an antidote to benzo overdoses, and has opposite effects to benzos, effects include lowering seizure threshold, anxiety, and agitation
flumazenil is an antidote to benzo overdoses, and has opposite effects to benzos, effects include lowering seizure threshold, anxiety, and agitation
so they're using an antibenzo to make people have *more powerful seizures* to make electroconvulsive therapy more effective. this is batshit
Treatment with flumazenil in this benzodiazepine-free older patient yielded improved quality and duration of seizures with ECT, with corresponding clinical response. He had no side effects, did not require further interventions, and recovery time was not affected.
it WORKED
it WORKED
