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Is serum LA a good marker of the health benefits of n-6 fats?

"Oxidation of LDL led to initial rapid depletion of [PUFA]s in phospholipids followed by extensive loss of [PUFA]s in cholesteryl esters and triglycerides."

ncbi.nlm.nih.gov/pmc/articles/P…

@DaveKeto
This is a fundamental problem w/ much nutritional epidemiology. If you don't understand the process you're looking at, you can't do good epidemiology.

You wind up measuring the wrong stuff, and coming to a conclusion 180° from the truth. 🙄

@HarvardChanSPH
Since oxLDL, which is LDL from which PUFA has been oxidized, is a major CVD risk factor, measuring LA without also measuring oxLDL is wrong-headed.



Like claiming lots of bullets in a war zone indicates safety. They haven't pulled the triggers yet...
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