, 10 tweets, 3 min read Read on Twitter
Interesting basic metabolic. Don’t you think?
The hyponatremia is due to the hyperglycemia. #ProblemSolved
Don’t be deceived by the normal bicarbonate, there is an anion gap big enough to drive a truck.
The bicarbonate before reveals a massive pre-existing metabolic alkalosis. The anion gap metabolic acidosis completely covers it up leaving a Norma HCO3 of 24.
If you prefer a Gap-Gap analysis (or delta-gap), it likewise shows a massive pre-existing metabolic alkalosis.
Anyone think it will get simpler if I show you the VBG?
And yup, things gets murkier...respiratory alkalosis.
If you look at the compensation, if the respiratory alkalosis is chronic, then it is well compensated with an appropriate HCO3. If the respiratory alkalosis is acute then there is an additional metabolic acidosis (which we know about because of the anion gap)
In addition to some uremia, the anion gap seemed to be entirely due to DKA. We do not have serum ketones available in our hospital lab, so a urinalysis is the best we got. Sorry.
Jason Kidd, the nephrologist not the basketball player, nailed the diagnosis here:



No satisfactory explanation for the respiratory alkalosis beyond abdominal pain and mild liver disease.
Missing some Tweet in this thread?
You can try to force a refresh.

Like this thread? Get email updates or save it to PDF!

Subscribe to Joel Topf, MD FACP
Profile picture

Get real-time email alerts when new unrolls are available from this author!

This content may be removed anytime!

Twitter may remove this content at anytime, convert it as a PDF, save and print for later use!

Try unrolling a thread yourself!

how to unroll video

1) Follow Thread Reader App on Twitter so you can easily mention us!

2) Go to a Twitter thread (series of Tweets by the same owner) and mention us with a keyword "unroll" @threadreaderapp unroll

You can practice here first or read more on our help page!

Follow Us on Twitter!

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just three indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3.00/month or $30.00/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!