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A fine 2015 viene pubblicato questo studio
Menachery VD, Yount Jr. BL, Debbink K, et al.

“A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence”.

Nat Med. 2015 Dec;21(12):1508–1513. doi: 10.1038/nm.3985

Qui 👇

pubmed.ncbi.nlm.nih.gov/26552008/
Here we examine the disease potential of a SARS-like virus, SHC014-CoV, which is currently circulating in Chinese horseshoe bat populations. Using the SARS-CoV reverse genetics system, we generated and characterized a chimeric virus expressing the spike of ...
... of bat coronavirus SHC014 in a mouse-adapted SARS-CoV backbone.
(...) In vivo experiments demonstrate replication of the chimeric virus in mouse lung with notable pathogenesis.
On the basis of these findings, we synthetically re-derived an infectious full-length SHC014 recombinant virus and demonstrate robust viral replication both in vitro and in vivo.
Our work suggests a potential risk of SARS-CoV re-emergence from viruses currently circulating in bat populations.
*
Previsione centrata direi.
Altri studi negli anni seguenti hanno approfondito il tema.
Ad es.

Understanding bat SARS-like coronaviruses for the preparation of future coronavirus outbreaks — Implications for coronavirus vaccine development

Qui 👇
tandfonline.com/doi/full/10.10…
Contemporaneamente venivano sollevate perplessità sui rischi di queste ricerche. Gli Stati Uniti ad esempio ne sospesero I finanziamenti (circostanza cui si fa cenno nel primo articolo citato).
Un articolo di Declan Butler su Nature nel 2015 si sofferma sui rischi

Engineered bat virus stirs debate over risky research
Lab-made coronavirus related to SARS can infect human cells.

nature.com/news/engineere…
Opportunamente a marzo 2020 in premessa all’articolo citato viene riportata questa editors’ note
We are aware that this story is being used as the basis for unverified theories that the novel coronavirus causing COVID-19 was engineered. There is no evidence that this is true; scientists believe that an animal is the most likely source of the coronavirus
Non è un caso che di questi tempi giri una puntata del programma Rai Leonardo di novembre 2015 in cui si tratta del tema (min 4:53)

rai.it/dl/RaiTV/progr…
Scriveva @Declan_M_Butler degli esperimenti in corso, rappresentando le posizioni degli scienziati che evidenziavano l’utilità della ricerca, ma anche di quelli che evidenziavano i rischi
Ad esempio

Simon Wain-Hobson, a virologist at the Pasteur Institute in Paris, points out that the researchers have created a novel virus that “grows remarkably well” in human cells. “If the virus escaped, nobody could predict the trajectory,” he says.
Butler ricorda la moratoria negli Stati Uniti

nature.com/news/us-suspen…
C’è un fondamento alle immancabili tesi complottiste: si tratta di un virus costruito in laboratorio? Del risultato di quell’esperimento?
Al momento pare di no.
In particolare una recente ricerca lo escluderebbe

Shan-Lu Liu, Linda J. Saif, Susan R. Weiss & Lishan Su (2020)

No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2,

Emerging Microbes & Infections, 9:1, 505-507

Qui 👇

tandfonline.com/doi/full/10.10…
L’articolo prende in esame due possibili casi di fuga di virus da laboratorio: uno di origine cinese da Wuhan, ed uno di origine americana descritto nel primo tweet del thread (voce rilanciata da fonti cinesi).
In entrambi i casi non ci sono evidenze scientifiche.
The End
P.S. insomma per quanto ne sappiamo al momento nessun virus creato artificialmente da scienziati irresponsabili (siano essi Cinesi o Americani).
Solo punzecchiature mediatiche di cui si abbeverano complottisti di ogni dove
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