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May 5, 2020 15 tweets 6 min read Read on X
(1/15)
Q: What actually is #HerdImmunity anyway?

The #nerdygirls explain what it is and how it might be achieved in this thread
(2/15)
A: The term "herd immunity" refers to a situation where a lot of people in a population are not susceptible to a virus--either because they have already had it and are unlikely to get it again, or because they've been vaccinated.
(3/15) That is to say, their immune systems have been primed to respond to the virus, and they won't get infected with it when they are exposed again.
If a lot of people are immune, the virus has a hard time finding a host that it can infect, replicate, and spread to a new host.
(4/15) With herd immunity, even though *some* of the people in a population are susceptible to the disease, they're unlikely to be infected simply because they probably won't encounter the virus circulating in the population in the first place.
(5/15) Herd immunity is achieved when as many people as possible are vaccinated, which helps protect those who cannot or will not be vaccinated.

Herd immunity does not directly protect individual people from infection. It limits how fast a virus can spread through a population.
(6/15)
One reason why #COVID19 spread so rapidly around the world is because billions of people were susceptible.
Up until just a few months ago, *no one* had ever had it. That means everyone was susceptible and the virus had no trouble at all finding new hosts.
(7/15) What would it take to get to herd immunity for #COVIDー19 ? Many scientists think something like 70-80% of the population would need to have immunity to produce herd immunity.
(8/15) How do we get to herd immunity?

There are two routes: 1. vaccination and 2. natural herd immunity.

Both face major obstacles to becoming the magic bullet that stops the #pandemic right now. More on each below
(9/15)
1. A vaccine.
The safest path to herd immunity (and maybe the only way) is to develop #vaccines, so that we can become immune without ever having to be infected. A vaccine works by giving your #ImmuneSystem clues as to how to identify the virus before you encounter it.
(10/15)
But a vaccine is a long ways off--at least 18 months, and maybe much longer.

Even after a vaccine is approved, it will take years to cover enough people to really produce herd immunity. Staying home until a vaccine becomes available isn’t a realistic option.
(11/15)
2. “Natural” herd immunity.
Okay so a vaccine is too far off. What if we just let everyone get #Covid_19 ?
As epidemiologist Gideon Meyerowitz-Katz says, “...this is simply nonsense. Herd immunity without a vaccine is by definition not a preventative measure.”
(12/15)
If we just let everyone get the disease, then everyone is sick. That’s not stopping the spread of the disease--it’s encouraging it!
This let-it-burn approach to achieving herd immunity would require hundreds of millions of people to fall ill all at once.
(13/15)
If we guess conservatively at a 2% mortality rate, we’re talking about over 4 million deaths in the United States alone! YIKES.
Plus, we are still learning about the long-term health consequences of #COVID__19 infection for survivors.
(14/15)
Not only that, we don’t yet know if recovering from #COVID means you are immune to it in the future. In fact, rapid widespread infection could provide the virus just the opportunity it needs to mutate more rapidly--which could undermine herd immunity!

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More from @DearPandemic

Dec 22, 2022
How can I stay safe during the holidays?

➡️Think in terms of harm reduction. Don’t let the perfect be the enemy of the good.

dearpandemic.org/safe-holidays/

#covid #rsv #flu #HolidaysAreComing

1/
2/ Just in time for Christmas, #COVID is again on the rise.

#Flu and #RSV may be peaking—but remember that there are often as many cases *after* a peak as before it.

dearpandemic.org/are-cases-peak…
3/ How can we enjoy moments w/ family & friends & lower the risk of illness?

💥 Small steps you take to reduce risk are worthwhile. A little bit better…is a little bit better.

Prevention steps that work for COVID will reduce the risk of RSV, flu, & many other nasty viruses.
Read 14 tweets
May 4, 2022
1/ Q: Has almost everyone been infected with COVID by now?
A: Recent estimates suggest around 58% of the population in the US and over 70% in England have been previously infected, with BIG increases during the Omicron wave.

dearpandemic.org/numbers-infect…
2/ A recent @CDCgov MMWR report estimated seroprevalence from a convenience sample of blood collected for medical tests.

➡️Roughly 58% of Americans showed evidence of previous SARS-CoV-2 infection in their blood by Feb '22.

cdc.gov/mmwr/volumes/7…? Image
3/ ➡️ During the Omicron wave from December 2021-February 2022, this estimate increased from 33% to 58%.
➡️ Rates vary a lot by age, ranging from 33.2% for those over age 65 to 75% for those under age 18.

cdc.gov/mmwr/volumes/7… Image
Read 15 tweets
Apr 29, 2022
1/Q: Did getting exposed to fewer germs for the last 2 years weaken our immune systems?

We've been hearing this question a lot.
dearpandemic.org/fewer-germ-exp…
2/ Not likely. If your kids are suddenly getting sick a lot, this is likely due to “catching up” on exposures rather than a weakened immune system.
3/ Many families w/ young kids have been hunkered down for the better part of 2 years– a good % of a young child’s entire life. While isolation had *many* downsides, we can agree that not having to suction snot out of infant noses or clean up norovirus puke was a happy upside.
Read 18 tweets
Jan 27, 2022
1/ Q: Are cases peaking? That means it’s all downhill from here, right?

A: Sort of…. Remember that even if cases come down as quickly as they rise, there will be as many cases *after* the peak as before (think area under the curve).

dearpandemic.org/are-cases-peak…
2/ ➡️ And if the downward slope is *slower* than the rise, we will see *more* cases during the decline from a surge.
3/ Burning fast could be a silver lining of super transmissible #Omicron. Cases rose & fell quickly in S. Africa (w/ hospitalizations & deaths still lagging). The UK appears to have turned the Omicron corner. Many US states appear past their peak in cases, w/ regional variation:
Read 17 tweets
Dec 30, 2021
1/ Q: Case numbers are jumping QUICK! What should I be doing?

A: Share your gifts without sharing COVID. Helpful gestures come in many shapes.

dearpandemic.org/what-should-i-…

#Omicron #ThoseNerdyGirls
2/ One HUGE help: Cancel non-essential plans.

Unfortunately, this includes New Year’s Eve plans. The perfect storm of a new variant & holiday get-togethers is hitting communities & health care w/ FORCE! Testing is in short supply.
3/ Health care is under extreme pressure with surging cases. If you can avoid even one additional contact, you are helping. This is a temporary and urgent request (from a health care provider).

#MedTwitter #HCWs @IMPACT4HC
Read 10 tweets
Dec 21, 2021
1/ Q: Is it true that #Omicron is less severe than previous variants?

A: We HOPE so, but we don’t know yet. The evidence so far is mixed.

dearpandemic.org/is-omicron-les…
2/ We are WAY past due for some good variant news. But pinning our #Omicron hopes on a less virulent variant is not wise for 2 reasons:

1) It might not be less severe in those who are “immune naïve” (neither vaccinated nor with a previous infection—still millions of people).
3/ 2) Many more infections *even* if less severe can still lead to an avalanche of hospitalizations and deaths, and the risk of long Covid.

@AdamJKucharski raised this last December w/ the rise of Alpha:
Read 25 tweets

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