We have just completed a prospective observational study: "Clinical Trajectories of Acute Kidney Injury in Surgical Sepsis" to determine the long-term impacts of #AKI in #sepsis patients.
The delayed or incomplete recovery of acute organ dysfunction during sepsis is an important determinant of survival and functional recovery. Since the kidney is highly susceptible to acute dysfunction during sepsis, we studied trajectories of AKI to see how they affect outcomes.
This single-center prospective 1-year longitudinal cohort study included 239 septic patients hospitalized in a surgical ICU. Blood and urine samples were collected to characterize endothelial function, inflammation, and immunosuppression.