1/ An interesting editorial by Prof. MacIntyre, infectious disease professor at the @KirbyInstitute at @UNSW. Edited by @mariemcinerney.

She postulates on why the COVID pandemic response has been such a "catastrophic failure of many Western democracies".
croakey.org/the-hijacking-…
2/ For reference, Prof. MacIntyre wrote this scientific editorial with @rajah_mich on 'Scientific evidence supports aerosol transmission of SARS-CoV-2"
aricjournal.biomedcentral.com/articles/10.11…
3/ Much focus on importance of a #multidisciplinary approach. A few interesting quotes:

"The evidence is clear that SARS-COV-2 is airborne, yet guidelines in many countries do not yet reflect this, thus hampering the ability to control the spread and endangering health workers."
4/ "No aerosol scientists or engineers who understand transmission of respiratory viruses and movement of aerosols are on the WHO committee, and their expertise is not sought, prompting calls from scientists for WHO to acknowledge airborne transmission..."
5/ "The lack of experts on respiratory transmissible infection or aerosol science at the table meant that much of 2020 was spent on promotion of hygiene theatre, actively discouraging mask use and a resulting low awareness among the general public of [masks and ventilaion] ..."
6/ "There are many different disciplines relevant to pandemic control, incl. the sub-specialities of clinical medicine, epidemiology, basic science, drug development, public health, occupational health & aerosol science, all of which are needed to [control] ... this pandemic ..."

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More from @HuffmanLabDU

26 Jan
1/ A really good, short read on a very important topic, providing motivation and support for mandated, high-quality #mask-wearing.

By @sri_srikrishna @MonicaGandhi9 @Don_Milton & others = These people you should trust.
hbr.org/2021/01/a-3-st…
2/ COVID19 still very serious & "widespread vaccination is expected to take multiple years globally."

Key arguments from the article above ⬆️ concerning masks.

1. Launch an awareness blitz
2. Communicate about appropriate mask types
3. Prioritize distribution to the vulnerable.
3/ A really important, practical message to emphasize:

Disposable N95s had been in short supply & "have been largely reserved for health care workers. But N95s are now available [widely]."

Should help motivate use of N95s, which have high & standardized filtration efficiency.
Read 5 tweets
25 Jan
1/2 @DrLaPook on the importance of quality face coverings (i.e. N95s or even multiple mask layers), esp. as worrying COVID variants rise (via @linseymarr).

But wrt to multiple #mask layers; mask FIT and overall BREATHABILITY also critical, because ...
cbs.com/shows/cbs_even…
2/2 ... If it's hard to breath through a #mask, it is too restrictive/thick. Air (& aerosol) will always escape mask. If air exits via gaps rather than THROUGH layer(s), mask is ineffective!

E.g. watch where/how aerosol escapes this poorly-fitting mask
3/2 (bonus) Since mask fit is so so important (even for N95s), there are various strategies to help improve air flow *through* the mask layers & improve fit. This preprint paper shows improvement in mask filtration efficiency by adding a mask brace/fitter.
Read 4 tweets
15 Jan
Important new preprint from Lednicky et al. on #aerosol transmission of COVID

*Aerosol <0.25 - 10 μm collected in car driven by COVID-patient w/ mild symptoms
*Viable virus only detected in airborne particles in size range 0.25 – 0.5 μm

HT @DavidElfstrom
medrxiv.org/content/10.110…
Paper shows: "the potential risk of SARS-CoV-2 transmission by minimally symptomatic persons in the closed space inside of a car (w/ closed windows & air conditioning running), & suggest that a substantial component of that risk is via aerosolized virus."
medrxiv.org/content/10.110…
This 👇 earlier paper by the same Lednicky et al. (published Sept. 2020) showed viable (infectious) SARS-CoV-2 was present in aerosols within the hospital room of COVID-19 patients.

Both add to growing body of evidence of real-world COVID #aerosol risk.
ijidonline.com/article/S1201-…
Read 7 tweets
15 Jan
1/ Adding #ventilation helps reduce (but not remove!) aerosols & risk from COVID. One simple measure of ventilation is to keep #CO2 sufficiently low. Simple CO2 sensors can be <$150 and are easy to take with you.

One nice summary of consumer CO2 monitors:
bit.ly/monitorsCO2
2/ The idea is that indoor #CO2 comes primarily from people breathing out; but breathing also produces potentially infectious aerosols. So keeping #CO2 levels <800 ppm (or <600 ppm) means air is likely refreshed rapidly enough to keep aerosol risk low.
3/ There are lots of good resources & articles on improving #ventilation & for using #CO2 monitors for rough checks. This article by @B_resnick from months ago is worth a read as a broad overview on various topics related to air safety wrt COVID/aerosols.
vox.com/science-and-he…
Read 8 tweets
13 Jan
1/ Really great article that explains common misconceptions & myths about airborne viruses. Clear & easily readable.

Led by a #multidisciplinary slew of all-star scientists. If you trust anyone in the world on these topics, these are the people you trust.
journalofhospitalinfection.com/article/S0195-…
2/ Dispelled myths:

Myth 1: #Aerosols are droplets with a diameter < 5 μm
Myth 2: All particles > 5 μm fall within 1-2 m of the source
Myth 3: If it's short range, then it can't be airborne
Myth 4: If R0 isn't as large as for #measles, then it can't be airborne
3/ Dispelled myths:

Myth 5a: If it's #airborne then surgical #masks (or cloth face coverings) won't work
Myth 5b: The virus is only 100 nm (0.1 μm) in size so filters and masks won't work
Myth 6: Unless it grows in tissue culture, it's not infectious

#COVIDisAirborne
Read 5 tweets
17 Dec 20
1/ During July 2020 many worked quickly to scramble #COVID19 prep before the Fall classes. I helped model estimated COVID #aerosol risk as @UofDenver made plans. Not allowed then, but shared now in case it can prompt discussion for Winter prep.

Doc + 🧵:
bit.ly/3gVfMcu
2/ A key concern at the time (& still) was #music ensemble classroom activities, b/c it was obvious early on that #COVIDisAirborne and that #choir & wind instruments were likely to present high COVID #aerosol risk.

nfhs.org/articles/unpre…
3/ Using my version of an aerosol #boxmodel, I calculated probability that #SARSCoV2 could infect after breathed out by someone in specific classrooms. With this I could easily investigate best prevention bang for buck. I.e. Rehearsal duration? Wait time b/n classes? Etc.
Read 20 tweets

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