[Thread] 1. Would criminals steal and falsify #CovidVaccines in #Africa? It has started. On 19 November, South Africa received its first freight of falsified #Covid19 “vaccines”. bit.ly/3qcHXYm
2. The falsified #CovidVaccines were found in a warehouse in Germiston. Police tracked the freight from OR Tambo and found prefilled syringes in boxes with Chinese labels. There were strong signs they were going to be sold as genuine #CovidVaccines. bit.ly/3qcHXYm
3. Interpol says the falsified "jabs" had been advertised for sale on a Chinese social media app, WeChat. They had been imported from Singapore as “cosmetic injections”. Two people have been arrested. Police are trying to trace if any were released in SA. bit.ly/3qcHXYm
4. On 15 January, Nigeria’s National Agency for Food and Drug Administration and Control said it was aware of falsified vaccines circulating in the country and pleaded with the public to beware: “Fake vaccines … could kill.” bit.ly/2MViCDS
5. Just 2 weeks later, “Dr H. Losho from Lagos”, who also advertises sex toys, clothes and shoes, posted this tweet: “If you're interested in 2 shots of Covid Vaccine at 50k each, contact @ad_de_moles. AstraZeneca. Arrives in 2 weeks. You get a card.” bit.ly/3cZzOTn
6. Why is Africa vulnerable to #CovidCrime? In an analysis in November, the WHO warned that “Africa is far from ready for what will be the continent’s largest ever immunisation drive”. bit.ly/2Z8H5bm
7. Lack of resources and technical capacity in #Africa means it’s going to take long for #CovidVaccine roll-outs to happen, says @RGAMeyer. Criminals will have time to strategise, adapt to security measures and to insert their products into supply chains. bit.ly/3qcHXYm
9. @RGAMeyer won an Emmy for a film Sweet Codeine (about illegal selling of the substance), resulting in several arrests and convictions, including that of a pharmaceutical company executive. bbc.in/3jFup53
10. Because the demand for #CovidVaccines will be high, access will be limited, everybody will want to have their shot, and in that kind of situation this vaccine is liquid gold, experts say. bit.ly/3qcHXYm
11. Only 10% of African medicine regulators have “moderately developed capacity”, with 90% having “little to no capacity”. The WHO says this “facilitates the proliferation of...falsely labelled, falsified and counterfeit medical products.” bit.ly/3qcHXYm
11. But where do counterfeit medical products that end up in #Africa come from? #China (Africa’s biggest trade partner) and #India. bit.ly/3qcHXYm
12. Anti-crime agencies say Africa’s trade routes with China/India will allow criminals to introduce shipments of falsified vaccines. Ex-trafficker: “There’s a well-established route for [illegal] tramadol between Nigeria + India that's waiting to be fueled with (fake) vaccine”.
13. So how can we protect our #CovidVaccines from being stolen or prevent falsified jabs from entering countries in Africa? Background checks on staff, GPS trackers inside vaccine boxes and verification technology. bit.ly/3qcHXYm
14. Read our full story. @bhekisisa_MG is grateful for the support of @GI_TOC for this investigative series on #COVID19 and organised crime. The next investigation will be published Thursday, 18 Feb. bit.ly/3qcHXYm
[Thread] 1. SA will be getting Pfizer jabs to use in #VaccineRolloutSA. Those jabs need to be stored in special freezers at -70 degrees Celsius. We don't have many of those freezers. So how will SA cope?
2. #Mkhize: Pfizer is sending its #CovidVaccines to SA in packaging that allows for the jabs to remain stable for a certain period until they get to a freezer. We've also had companies offering us access to the special freezers required so we can store the jabs safely.
3. Here's more background on the challenges with maintaining the cold chain with Pfizer jabs (some of these challenges have now been addressed with packaging that keeps the jabs at the right temp and more freezers that have become available). bit.ly/3q8UFHs
#Mkhize: The process of Aspen (in SA) filling and packing Johnson&Johnson #CovidVaccines is going well. We anticipate they will have their first batch ready in March. They need to hold manufactured stock for a month (safety procedure) before it can be released.
#Mkhize: Aspen says they want to serve SA and make Johnson&Johnson vaccines available to the country. But it's J&J who decides if, and how many, of the vaccines packaged by Aspen in SA our country can get.
#Mkhize: J&J has told me they're committed to making their #CovidVaccines available to SA. (On Sunday, principal investigator Glenda Gray said J&J will make an announcement about this later this week).
#Mkhize: [Thread] We want to use the best #CovidVaccine for SA. The #501YV2 variant has impacted on the efficacy of jabs. The results showing the impact on the #astrazenecavaccine only became available on Fri. We now know it doesn't prevent mild/moderate #COVID19 disease in SA.
#Mkhize: Government's process of procuring the #AstraZenecaVaccine started before the new results on lack of efficacy in South Africa became available.
#Mkhize: The public has concerns about the expiry date of the #AstraZenecaVaccine. The vaccine has not expired yet. The doses would have been used up by the April expiry date with our original #VaccineforSouthAfrica roll-out strategy.
Madhi: When researchers looked at protection that the #AstraZeneca jab provided against mild to moderate #Covid19 disease, there was considerable protection against the original form of the virus. But the antibodies induced by the jab didn't work nearly as well for #501YV2.
There was very little difference between the protection the vaccine provided for people infected with #501YV2 and the placebo group (the group that was infected with a saline solution instead of the #AstraZeneca vaccine).
Madhi's team found that the #AstraZeneca vaccine provided almost no protection against the #501YV2 variant, also known as the #B1351 variant. There is hope: the Johnson&Johnson (Jansen) jab provides 89% protection against severe #Covid19 caused by #501YV2.
.@ShabirMadh, principal investigator of the SA arm of the #astrazenecavaccine: This slide explains who participated in the SA arm of the study: Adults between 18 and 65, everyone got 2 doses, 2000 participants. To show protection we need 60% protection, Madhi says.
The Oxford/AstraZeneca study wasn't designed to determine whether the vaccine protects against severe #COVID19 disease or not. Rather, it looked at mild to moderate disease.
Those who develop severe disease are the ones who will end up in hospital or die - it's important that vaccines protect against severe disease. But our study only looked at if the vaccine protects against mild and moderate #COVID19 disease.
[Thread] 1. NEW Early data (not yet peer reviewed) shows the #AstraZeneca#CovidVaccine, that SA will start to administer this month, doesn't appear to offer protection against mild/moderate disease caused by the #501YV2 variant identified in the country. bit.ly/3pZ30xx
2. Mild disease #COVID19 disease was defined as at least one symptom of COVID-19. Protection against moderate-severe COVID19, hospitalisation or death was not assessed in this study as the target population were at low risk (they were young and healthy - on average 31 years old).
3. The study results, which will be submitted as a preprint in the coming days, show two doses of the #AstraZeneca jab did have high efficacy against the original coronavirus non-#501YV2 variants in South Africa. bit.ly/3pZ30xx