Interesting challenge study in Brazil—

A small town in Brazil is running a #COVID19 vaccine science study street by street aiming to track the real-world impact of a vaccine in halting transmission. They are testing SinoVac’s CoronaVac.🧵

HT @djknowles22
2) Serrana – a sleepy town in São Paulo state home to some 45,000 people – was chosen last autumn to host ‘Project S’, an unprecedented study that aims to answer looming questions about the real-world impacts of coronavirus jabs.
3) By vaccinating the entire city in stages researchers hope to track whether someone who is inoculated can still transmit the virus, and how quickly vaccines contain the pandemic.
4) “We expect vaccines to make the disease manageable, an infection that we can live with,” said Dr Ricardo Palacios, of Butantan Institute, which leads the research. “But we need to test this in the real world to identify whether vaccines reduce severe disease and transmission.
5) That’s our aim: to study this in a manageable, controlled setting and provide the data needed to make future public health decisions – like when is a good time to stop social distancing or face masks, based on vaccination rates?”


telegraph.co.uk/global-health/…

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More from @DrEricDing

1 Apr
YOUNG ADULTS MOST AFFECTED—Long-Covid symptoms are affecting about 1.1 million people in the U.K., with about half that number saying the disease is harming their day-to-day lives, government statistics show. Top #LongCovid age group? 25-34! Thread 🧵
bloomberg.com/news/articles/…
2) “About 196,000 of those people said their ability to undertake regular activities was significantly impacted, the Office for National Statistics said on Thursday. The figures detail those still grappling with the coronavirus after four weeks and were self-reported to doctors.
3) The figures mark the first time the ONS has analyzed how the pandemic will affect the population over time. More women than men had lingering affects from the disease, and more young people than older ones were suffering.
Read 9 tweets
1 Apr
“Bloodbath is imminent” if we don’t act—A UN special envoy warned the 15-nation Security Council on Wednesday that "a bloodbath is imminent" in Myanmar if it does not act to curb the violent military crackdown against protesters. #Myanmar (HT @PamelaFalk)
cbsnews.com/news/myanmar-u…
2) "Looking back ten years from now, how will history judge this inaction?" Special Envoy of the Secretary-General Christine Schraner Burgener asked the diplomats. "I hope you can act while there is still time to avoid the worst outcome by overcoming caution and disagreement."
3) violence in Myanmar, sparked by February 1 coup of the nation's democratically elected leader, intensified over the weekend, when activists say more than 100 people were killed by the military junta's security forces in what appeared to be the bloodiest day yet of the conflict
Read 4 tweets
31 Mar
This is unfortunate—a Baltimore manufacturer two #COVID19 vaccines accidentally conflated ingredients several weeks ago, ruining about 15 million doses of Johnson & Johnson’s vaccine and forcing regulators to delay authorization of production lines.
nytimes.com/2021/03/31/wor…
2) “The mixup has halted future shipments of Johnson & Johnson doses in the United States while the Food and Drug Administration investigates. Johnson & Johnson has moved to strengthen its control over Emergent BioSolutions’ work to avoid further quality lapses.
3) “The mistake is a major embarrassment for Johnson & Johnson, whose one-dose vaccine has been credited with speeding up the national immunization program.
It does not affect Johnson & Johnson doses that are currently being delivered and used nationwide.
Read 7 tweets
31 Mar
BREAKING—France 🇫🇷 schools to close for at least 3 weeks (remote) under 3rd lockdown. Cases surging. Variants now dominant, especially #B117 variant that has higher infection in kids versus the old strain (higher %increase than adults vs old common). bbc.co.uk/news/world-eur… Image
2) here is why France went into lockdown again. Cases surging. Image
3) To be clear—it’s all schools—nurseries, schools, colleges and high schools will close for three weeks in France. And nightly curfew and a ban on going more than 10 kilometres from home.

google.com/amp/s/www.euro…
Read 7 tweets
31 Mar
DISGUSTED beyond words. A 65 year old Asian lady brutally kicked and beaten in broad daylight in Manhattan. Worse—3 bystanders did nothing!! Even more worse—the security guard closed the door to ignore it!! She is still hospitalized with fractured pelvis.
2) it’s so scary for Asian Americans right now that @AndrewYang is advising no Asians walk outside alone—only go out in pairs. #StopAsianHate

nytimes.com/2021/03/30/nyr…
3) “Reports of anti-Asian hate crimes have risen sharply during the pandemic, often triggered by people falsely blaming Asian-Americans for spreading the coronavirus, according to police departments across the country.
Read 10 tweets
31 Mar
Um, this is totally WRONG.

@CDCDirector: “Our data from CDC today suggest that vaccinated people do not carry the virus.”

We have lots of data you can often still carry it. Fauci even says so.

I love the CDC—but they may have to walk this back. #COVID19
2) 90% efficacy for the mRNA vaccines against infection is *not* 100%. This is why Fauci says we still need to mask if vaccinated. Image
3) Why am I nitpicking? Because this is important. Saying “you don’t carry the virus” is what right wing anti mask people say those vaccinated. This is what Rand Paul says to justify no masks. And for asymptomatic cases, protection is not perfect either. academic.oup.com/cid/advance-ar…
Read 5 tweets

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