ICYMI, a reminder that this pandemic will have a lasting legacy beyond the tragedy of the countless lost lives and grieving families. Results from the #COVERSCAN study on #longcovid reports that organ impairment was detected in post COVID patients as shown in the figure below
This included damage to the #heart, #lungs, #kidneys, #liver, #pancreas and #spleen In almost a third of patients, damage in 2 or more organs was identified. In particular, damage to the liver, heart or lungs was associated with further organ impairment.
The participants in this study were all considered to be previously at low risk of #mortality and had no #comorbidities. bmjopen.bmj.com/content/11/3/e…
The next figure shows the links between symptoms and organ impairment. It shows that damage in particular organs was associated with particular symptoms, i.e., pancreas: diarrhoea, fever, headache and breathlessness
Overall, the group report that in low-risk individuals, there were chronic symptoms and mild impairment in the heart, lung, liver, kidney and pancreas 4 months post-COVID-19, compared with healthy controls, indicating a physiological basis
Long COVID is likely to represent a huge challenge, both for those suffering, and for health resources to support and manage those effectively. Thank you to the team at COVERSCAN for their continuing analysis coverscan.com

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More from @NicolaMedical

6 Mar
THREAD
Are the social distancing measures damaging our immune systems? Less contact = reduced infection rates.
For example, the number of reported whooping cough cases during the reporting period 2020/2021 is less than 5% of that of the previous year
1/
@PHE produce weekly updates on statutory notifiable diseases and usefully provide comparisons to previous years. As might be expected, there has been significant decline in all. A few more graphs below to illustrate this 👇
2/
As well as whooping cough, there are significantly fewer reported cases of #meningococcal septicemia, acute #meningitis, #measles and #mumps
3/
Read 13 tweets
11 Feb
THREAD
Social distancing measures have not only reduced transmission of SARS-CoV-2, but also of the flu as seen here in this remarkable chart. Note the absence of any ‘spike’ in the 2020/2021 season indicated by the red arrow.
How have these measures impacted other viruses?
1/
@PHE_uk publish regular surveillance of Norovirus & Rotavirus, two viruses responsible for most cases of vomiting and diarrhoea in children & adults. Rotavirus is typically seen in young children.
2/
Note the remarkable decline in norovirus cases 2020/21 in this next figure vs. what might usually be expected
3/ Norovirus lab reports in England by week during 2019/2020 an
Read 7 tweets
30 May 20
THREAD
The latest @ICNARC report on ICU admissions was published last night, and on behalf of @ICS_updates and @COVID19actuary, please read this thread for an update
1/
There have been 321 new notifications of patients admitted to ICU with confirmed #COVID__19 . (9347 in total) This is largely static compared to last week, but still around 40% of 2 years’ worth of viral pneumonia admissions in ‘normal’ times
2/
The distribution according to critical care network remains unchanged with London and the SE showing the greatest number of admissions. The new admissions this week appear to be concentrated in the London – South ODN
3/
Read 15 tweets
9 May 20
THREAD
The latest @ICNARC report is now out with, for the first time, multivariate analysis. So, stepping into @ActuaryByDay shoes, here’s the summary, and a link to the full report. icnarc.org/Our-Audit/Audi… @COVID19actuary @ICS_updates
1/
The report captures all patients in E & W with confirmed COVID-19 admitted to ICU up until 4pm on 7 May 2020 where outcome data is available. So far, of the 10,758 notified admissions, 6143 have outcomes reported and 2107 are still receiving critical care
2/
The downward trend for admissions to ICU continues; the effects of social distancing evident
3/
Read 13 tweets

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