2/7 Metered dose inhaler (MDIs) are best used with a spacer! Pressurized devices were invented far earlier, but the technology was adapted to treat asthma in the form of an MDI in 1957 by Riker Labs. smithsonianmag.com/innovation/his…
4/7 Here is a fantastic review about spacers, including an overview and considerations of different spacer characteristics. ow.ly/EDs730keDOw
5/7 The CDC has a nice fact sheet about proper spacer use. Given how many steps there are, it’s not surprising that they are not used with perfect technique! cdc.gov/asthma/pdfs/In…
6/7 An article from CHEST in 1989 even suggests that MDIs might be as effective as nebulizers (specifically in sympathomimetics)! doi.org/10.1378/chest.…
7/7 In summary:
1️⃣ MDIs are the only type of inhaler that require a spacer
2️⃣ Spacers can be beneficial if used with proper technique
3️⃣ Proper technique is very difficult to execute
Please share any thoughts!
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1/7 Let’s go over the evidence-based physical exam for lower extremity deep vein thrombosis (LE DVT). In the spirit of quantifying clinical concern, here is a question - besides inspection (and #POCUS), which tool will help you the most?
Quick review of LRs:
- The (+) and (-) indicate the LR if a finding is present or absent, respectively
- The more the LR deviates from 1, the more useful it is
3/7 For this particular set of exam findings, it may be more helpful to see how much the LRs change your post-test probability (assuming a pre-test probability of 50%). The presence of absence of asymmetric calf swelling seems to be the most helpful.
1/4
Let's review the evidence-based physical exam for Cushing syndrome!
Quick review of LRs:
- The (+) and (-) indicate the LR if a finding is present or absent, respectively
- The more the LR deviates from 1, the more useful it is
2/4
Things that stand out to me
- "Buffalo hump" doesn't have a defined LRs despite being taught as a "classic" finding (occurs in 34-75% of patients)
- The presence of moon facies has a lower LR than I expected (1.6)
3/4 - The absence (or presence) of abdominal striae is not particularly helpful
- The presence of a thin skinfold (thickness on the back of the hand <1.8 mm in women of reproductive age) can be VERY telling
2/ What are the Weber and Rinne tests used to help identify?
3/ The answer is both! Remember that the most useful exams are hypothesis-driven so you need to do a history to begin suspecting if a patient has either type of hearing loss. This will help you generate a pre-test probability for disease (this will become relevant later).
2/8 First of all, a quick reminder that the utility of the FeNa and FeUrea in evaluation of AKI needs to be carefully considered before they are ordered (I'm a big fan of looking at UAs). journalofhospitalmedicine.com/jhospmed/artic…
3/8 You might see a table like the one below that can be used to (cautiously) interpret FENa and FEUrea.
1/11 Congrats to those who matched! I tweeted about an inpatient pocket card set in 2020 and got great feedback. Here is the result of a big overhaul: bit.ly/pocketcardset
1/14 I was always asked as a student if I wanted to give fluids to a patient, but no one ever told me how they think about. Here is my approach to giving IV fluids.
Disclaimer: Things are simplified for the sake of pragmatism.
2/14 I call my approach an "IV fluid timeout." It involves asking yourself four questions before giving someone IV fluids.
3/14 I broke down the answer two question one into two major buckets. This is the most important question because if a patient does not need IV fluids, do not give IV fluids.