2/ I’m wondering if there are still people around today who would be able to do something like E04DGF and CVode. I doubt that anything has improved at those levels. Is E04DGF still the fastest?
3/ The problem is also, that SW will come and bite the semiconductors, so the HW itself. After having done some work with Cadence I can only say: what a mess. It’s a patch and collection of pieces that they have procured over time. But nothing is consistent across modules.
4/ Back in 2001, we were still working somewhat low level and taking care in optimization of solvers. But the progress of HW made us lazy. Waiting 6 months for the better HW had better results than trying to squeeze out performance by e.g. preconditioning differential equations,
5/ ..the mathematical problem, e.g. by conditioning the matrices to make CVode run faster. My own laziness exploded in 2003 when I switched to Python from C++. More productive in coding, but a waste of HW use performance. I have never written a C++ line of code since then. 🤷
6/ I think that both SW and HW will collapse rapidly at some point. So what will happen then to:
electric cars
digital money
data in some cloud
digital workplace at home
communication devices
vax passport 🤡
Buy a book about hunting, gathering and farming I recommend.
7/ Today people learn coding using Jupyter notebooks. Good night I say. I hate it, but that’s where I ended too. Those people starting like this will never go down to low level or write a consistent piece of object oriented complex software.
8/ Today society has stopped valuing mathematics and intelligence as the most important skill for hiring. Instead even VC firms and startups are implementing the deadly intersectional equity cult. That will end in self destruction.
9/ The entire society is moving away from merit and skills towards the self destructive equity. Schools, politics, media, everywhere. That’s why we are unable to “solve”, understand the Covid crises. Stupidity is everywhere. We are going down. Inevitably. But it’s exciting too.
Die Folge mit Mastermind Prof. Kremsner war genial. Ich habe mich zu tode gelacht. Er spielte mit Lanz wie eine Katze mit der Maus. Minimale Antworten. Man konnte so richtig sehen wie es im Gehirn von Lanz gearbeitet hat. 😂 Ab Minute 55
Lanz: Was war das Problem mit Curevac?
K: Die Dosis.
L: Was war denn das Problem.
K: Zu niedrig.
L: Ja aber dann kann man das einfach höher machen.
K: Wie ich gesagt habe bei 12 µg war bei Phase eins das Limit wegen Nebenwirkungen.
L: Und Dosis von bei den anderen? 😂👏
2/ The story is interesting. It seems to have been long clear, that the unmodified approach isn't working. The immune system attacks unmodified RNA making higher (effective) dosing impossible.
3/ Both #Moderna and #Biontech used #Pseudouridin which allows them to have 10x higher dosage compared with the unmodified approach. The media further state, that the dose was "unfortunately" chosen too low in the CureVac trial.
1/ A great summary! After having peer reviewed many papers in the past, I can't leave this uncommented. There is just too much truth in it. But also many things missing. @markdhumphries
2/ "only one of Einstein’s 300 or so published papers was ever peer-reviewed, which so disgusted him that he never submitted a paper to that journal again."
He was not alone. Nature rejected Kary Mullis PCR paper (Nobel Price awared).
3/ Peer Review is nothing more than "please have a look". It's a basic check, not a quality endorsment. Most papers I received were Chinese low quality papers pushing into high-end journals like Phys. Rev. B or Phys. Rev. Letters. I rejected (or redirected elswhere) most of them.
Das hier ist ein großer Vertuschungsskandal, insbesondere kombiniert mit dem „Ermächtigungsgesetz“ 2.0 der sich Notbremse nennt. Der Flyer erklärt das Testproblem sehr anschaulich.
2/ Der Flyer ist eine gute Darstellung vom Satz von Bayes. Vor der bundeseinheitlichen Notbremse war er noch aufzufinden. Jetzt mit ist es aus dem Netz verschwunden. Es visualisiert dass es zu ewigen „locked-in“ Ausgangsperren kommen kann, alleine mit falsch positiven Tests.
3/ Gegen das neue Gesetzt (eine Groteske basierend auf nicht wissenschaftlichen Methoden) kann nur per Bundesverfassungsgericht vorgegangen werden, und nur als Einzelperson. Sammelklagen sind ausgeschlossen.
1/ @ZDFMarkusLanz liefert wieder esoterische Real Satire. @DirkBrockmann der Clown. Entdeckungen der Physik hat unsere Leben verändert. Die #Covid Pandemie, hat leider die inkompetentesten Kollegen zum Vorschein gebracht.
2/ Ich bin entsetz, dass gerade inkompetente Physiker (@ViolaPriesemann@CorneliusRoemer etc.) zur Zerstörung der Gesellschaft beigetragen haben. Friedrich Dürrenmatt, wenn am Leben, würde „Die Physiker 2“ schreiben. Diesmal mit solchen, die wirklich in die Psychiatrie gehören.
3/ Lanz: “War es vielleicht ein Fehler zu viel auf Physik, Mathematik und Modellierer“ zu hören? Offensichtlich schon, wenn man die verrücktesten einlädt. Laden Sie mal Prof. Wiesendanger oder @MLevitt_NP2013 ein. Tipp: h-index < 70 NICHT(!) einladen.