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More from @fabiohasler92

8 Dec
Neutralization data for #omicron is out. By request of @andrew_croxford, I try to explain how scientists investigate #neutralization. First, it's lab-based data. It’s impossible to directly conclude from neutralization data that #vaccines will not work anymore in the field. 1/X
@andrew_croxford Second, assays are legion! I developed one myself, which is different to the one used by the lab of e.g., @CiesekSandra, in terms of #virus, incubation times, etc. Keep that in mind if you compare two papers directly. I will explain how I did my assay. 2/X
@andrew_croxford @CiesekSandra Third, you must understand that such an assay generates data about neutralization of the virus by antibodies in the serum. These assays do not allow for measuring the effect of e.g., T cells or memory B cells.
@sailorrooscout talks about that here: 3/X
Read 25 tweets
13 Apr
Der #Selbsttest und meine Gedanken, warum die Kritiker und Kritikerinnen häufig einen 🍏🍐 Vergleich machen. Es lohnt sich, @michaelmina_lab zu folgen. Er und sein Labor publizieren laufend zu #RapidAntigenTests in Fachjournals. #COVID19 #Coronavirus 1/X
Erstens, der Vergleich mit #PCR hinkt. Man will mit #Selbsttests nicht die gleichen Personen finden. Mit PCR will man #Infizierte finden. Der Test ist so sensitiv, dass man auch Infizierte findet, die noch sehr wenig Virus haben, oder deren Infektion 2 Wochen alt ist. 2/X
Selbsttests hingegen sind viel einfacher in der Handhabung als PCR und eignen sich für #Screening. #Selbsttests haben eine Stärke: sie erkennen hohe Mengen an #Virus, das heisst Personen mit hoher #Viruslast. Diese sind nachgewiesen diejenigen mit hoher Übertragungsgefahr. 3/X
Read 12 tweets

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