Dr K Fearnley Profile picture
Jun 15 7 tweets 9 min read
1/ I politely and urgently request for the name of Dr Amy Proal @microbeminded2 to also be added. If she is willing, it is essential Dr Proal also be given a seat at the #ME round table. @LucyChappell2 @sajidjavid
2/ Dr Proal is a strong ally of patients with #ME. Having experienced the illness herself, she has a unique understanding of the condition which she is using to inform hypotheses.
3/ Alongside others, she recently published pioneering work which showed #microclots in the blood of those with #ME.
4/ She is now working hard to search for viral persistence in tissues. This is **world leading research** which must be funded.

I would not request for the name of Amy Proal @microbeminded2 to be added if I did not think it was absolutely necessary. @LucyChappell2 @sajidjavid
5/ #ME #MyalgicEncephalomyelitis #MECFS #millionsmissings please get behind this. 🙏🏽 For too long this condition has been neglected. Having experienced #ME for yourself you will know this is not just tiredness but tissue hypoxia.
6/ Our tissues are oxygen starved. Micro clots and autoimmunity are likely downstream processes of viral persistence. Now is our chance to prove this. Let’s find a cure. #LongCovid #longEBV #LongCMV #LongLyme

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More from @fearnley_k

Jun 17
💥NEW PREPRINT from Harvard: #viralpersistence #LongCovid

Persistent circulating SARS-CoV-2 spike is associated with post-acute COVID-19 sequelae

🧵

medrxiv.org/content/10.110…
2/ Plasma samples were collected from a cohort of 63 individuals previously infected with #SARSCoV2, 37 of whom were diagnosed with #LongCovid (PASC) & 26 recovered.
3/ In the PASC group (n=37) , blood samples were collected multiple times up to 12 months after first positive result.

In those individuals recovered (n=26), blood samples were collected up to 5 months post diagnosis.
Read 13 tweets
Jun 15
I see @TorbaySDevonNHS have abandoned their legal & professional responsibility to keep patients safe.#CovidIsNotOver Case & hospital numbers are steeply rising. As we enter the 3rd wave of the yr, I urge you to put your #FFP3 mask back on & demand your trusts invest in #CleanAir
Exposure to #COVID19 can cause neurodevelopmental delay
Read 4 tweets
Jun 5
🚨 Can anyone who lives local to Southcote Road, BOSCOMBE, Bournemouth, check on the welfare of these dogs? Update below. @rickygervais @PeterEgan6 @domdyer70
This morning I have contacted Dorset Police and the RSPCA.
@Dorsetpolice confirmed the incident had been reported to them, but because I am not the dog owner or the car owner, they said they cannot give me any details of the case.
Read 9 tweets
Jun 5
New preprint:

Long COVID is associated with extensive in-vivo neuroinflammation on [18F]DPA-714 PET

medrxiv.org/content/10.110…
A significant number of COVID-19 patients develop ‘long COVID’, a condition defined by long-lasting debilitating, often neurological, symptoms.
Post-mortem histopathological studies have shown extensive inflammatory responses in organs of patients with acute COVID-19, including the brain. Postmortem studies reveal diffuse microglia activation predominantly in the olfactory bulbs, medulla oblongata, brainstem & cerebellum
Read 23 tweets

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