Discover and read the best of Twitter Threads about #viralpersistence

Most recents (14)

Do you have #longcovid and feel that your symptons align with that indicating #viralpersistence? Did you know a lot of research indicates that's what's wrong with us? There is some hope. Read on. 🧵
Read 9 tweets
Reality check:

1. You can catch Covid multiple times.
2. Reinfections are common, not rare.
3. Breakthrough infections are common.
Read 11 tweets
1/ Long Covid community!! I am SO excited to share with you the launch of the

💥Long Covid Research Initiative

2/ The LCRI is a collaboration between Long Covid patients, researchers, and clinicians to rapidly and comprehensively study the topic of SARSCoV2 #viralpersistence in Long Covid and the general population.
3/ The organisation was founded by patients and those with close ties to condition, and the research programme is being led by Chief Scientific Officer @microbeminded2.
Read 19 tweets
AGAIN - 🦠🦠🦠
“When comparing patients with post-COVID symptoms and patients without, we found that Spike protein and viral RNA were more likely to be present in patients with PASC and in some cases at higher levels compared to acute COVID-19 patients.”…

“The levels of SARS-CoV-2 Spike protein in the plasma and EV samples were determined using the SAR-CoV-2 (2019-nCoV) Spike protein ELISA Kit according to the manufacturer instructions (SinoBiological).”
“We grouped PASC patients into PASC-positive (n=33) and PASC-negative (n=14).

When we examined the viral RNA copies in the plasma from PASC+ve and PASC-ve individuals, 28% of PASC-ve samples showed presence of viral RNA copies…”
Read 12 tweets
1/ Public health messaging has failed to warn the public on:

➡️ Long term infection harms

➡️ How to protect oneself from infection

Given we’re at the start of a new wave, case numbers & rates of hospitalisation are rapidly rising, here’s a

⚠️ public health warning ⚠️

This message is important to everyone, but is especially pertinent to those who erroneously believe #LongCovid is ‘just tiredness after infection’ and it won’t happen to them because they’ve had it and ‘it was just a cold’
First let’s discuss #LongCovid.

Long Covid is a chronic, multi organ, physical condition, currently absent of treatment or cure.

Latest figures show 2M ppl in the UK are affected. 376K have now been unwell for >2 yrs. While some slowly improve, recovery is not guaranteed.
Read 27 tweets
Long Covid is no longer a mystery: Long Covid IS Covid. 👇🏼
We can learn from previous pandemics and emerging evidence.
Autoimmunity and abnormal clotting are likely downstream processes of #viralpersistence - whether that be in the form of intracellular viral reservoirs, viral debris or synthetic vaccine spike.
Read 5 tweets
💥NEW PREPRINT from Harvard: #viralpersistence #LongCovid

Persistent circulating SARS-CoV-2 spike is associated with post-acute COVID-19 sequelae

2/ Plasma samples were collected from a cohort of 63 individuals previously infected with #SARSCoV2, 37 of whom were diagnosed with #LongCovid (PASC) & 26 recovered.
3/ In the PASC group (n=37) , blood samples were collected multiple times up to 12 months after first positive result.

In those individuals recovered (n=26), blood samples were collected up to 5 months post diagnosis.
Read 14 tweets
Dogs to the rescue! 🦮 @Em23397 Emilie Seyrat’s amazing SARS-CoV-2 sniffer dogs study, now covered by ⁦@TIME⁩ highlighting the enormous potential for fast & accurate screening, of both acute- and #LongCovid.
Almost any dog can be trained to do this type of detection in a matter of weeks, @dgrandjean says. “We could have hundreds or thousands of dogs doing this for almost [no money], and they would be as efficient as PCR”
Canines in (this) study detected evidence of the virus in samples from 23 out of 45 Long COVID patients…but not among any of the sweat samples that came from 188 people without Long COVID. That accuracy rate may be an underestimate, says co-author Emilie Seyrat @Em23397
Read 7 tweets
1/ Important thread.

Why UK government failure to acknowledge & invest in #LongCovid will have irreparable health & economic consequences. 🧵

@Conservatives @UKLabour @LibDems @LSHTM @markjit @AnnaVassall
2/ In April 2021, #LongCovidKids hand delivered letters to Prime Minister, @BorisJohnson, requesting investment & treatment for #LongCovid.
Read 23 tweets
1/ An important thread on Long Covid and #viralpersistence

“Almost all infectious outbreaks leave behind a proportion of pts who remain chronically unwell with symptom patterns similar to #LongCovid. This is known as the ‘long tail’ of epidemics.”

2/ Clues can be gained from studying survivors of the SARS (SARS CoV-1) outbreaks of the early 2000’s, and the West Africa Ebola crisis of the past decade.
3/ After SARS CoV-1 in 2002 - 2004, some survivors were reported to feel “weak, extremely fatigued, had aches and pains all over their body, and they were completely unable to work”

Some also reported ‘sleeping extremely poorly’.
Read 25 tweets
🚨Attention medics.🚨 An important thread on #MyalgicEncephalomyelitis Forget what you think you know. It is not psychosomatic. These pts are desperately physically unwell, likely with a chronic infection. #MedTwitter #MedEd #TeamGP 🧵 1/
Bedbound & housebound, they make up #millionsmissing. They maybe out of sight, but they are never far from my mind.

Neglect of #ME is the biggest medical scandal of the 21st century. The medical community will soon look back on their treatment of #pwME with horror & shame./2
But some Drs maybe forgiven for their ignorance. #ME fails to feature on the UK medical curriculum and as such, awareness & understanding is low.

The condition has also been highly stigmatised & erroneously - but deliberately - labelled psychological./3
Read 22 tweets
Antivirals in the treatment of Long Covid must urgently be trialled. @NIHRresearch @NIH @NIHDirector

Increasing evidence of #viralpersistence & anecdotal reports of LongCovid symptoms improving & resolving on antiviral therapy can no longer be ignored.…
Make no mistake, Long Covid is a public health emergency.

With 1.7 million people in the UK currently affected - many housebound/bedbound & now entering their third year of illness - there is no time to lose.

The situation is time critical.
Read 3 tweets
Happy to be a co-author of this article about #viralepersistence in #longCovid patients-found by dogs of @Env_Alfort- w/ Dominique GRANDJEAN, Dorsaf SLAMA, Capucine GALLET, Clothilde JULIEN, Marc BLONDOT, Maissa BENAZAZIEZ, Judith ELBAZ and Dominique SALMON #apresJ20 #Covid19
Dogs have already demonstrated high capacity in detecting Covid19 infection in acute phase (very high sensitivity)
Now they help demonstrating once more that #viralepersistence is present « in some Long Covid patient »..#apresJ20 #longCovid #Covidlong #Covid19 👇
I would like to explain why we wrote « at least in some Long Covid patients » : dogs positively discriminated half of the 45 people but there are surely much more #longCovid #Covidlong positive = with #viralepersistence #persistancevirale #apresJ20 👇
Read 23 tweets

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