FDA has extended emergency auth of Novavax #vaccine to age 12-17y. Given as 2 doses 3w apart, it was 78% effective in preventing confirmed symptomatic #COVID19 7d after dose 2. It is a protein-based vaccine like many familiar vaccines in use for decades, e.g. tetanus. #MedTwitter
Those under 18 are much less likely to be fully #vaccinated against #COVID19 than adults in the US, even though we now have vaccines authorized & recommended for kids as young as 6 mos. We'll see fewer kids missing school this fall/winter the more we #GetVaccinated now.
When I am trying to decide about something outside of #MedTwitter, I ask what professionals in that field do themselves. In case that approach is helpful to you, here's a poll.

Doctors: did you get your eligible kids #vaccinated against #COVID19?
Note most votes are for "see results." I mention it for 2 reasons: 1) if you tweet a poll targeted at 1 group, others will vote randomly to see results, messing up your poll, so include this option & 2) percentages need to be adjusted at end of poll to reflect true denominator.

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More from @tmprowell

Aug 3
I’m more cautious than @Bob_Wachter when it comes to #WearAMask indoors (basically always w/ ppl from outside my 🏡 except briefly when I have to eat). I share his🧵 because this approach is sound: choose deliberately knowing current trends & weighing risk vs benefits. I differ…
On one point: I don’t agree that “the tools now exist” means everyone has the tools. We know that #COVID19 treatments are being underutilized in low-income & minoritized groups. We know that the high-quality N95 😷 that Dr. Wachter concedes are tough to wear all day every day…
Are what is needed to optimally protect workers in high-risk settings (think public mass transit workers, etc). Each time any one of us chooses not to #WearAMask & risks getting infected, we make it more necessary for others to wear N95 level masks to stay safe from us.
Read 6 tweets
Jul 28
Please reply with a few words or a story about an amazing nurse in your life. Patients, caregivers, #MedTwitter or #NurseTwitter, chime in. Our nurse colleagues are exhausted in this #pandemic & need to know how much they are appreciated. Bring it.
I’ll start. I want to recognize Mary Evans at @HopkinsGynOb. With my firstborn, I had a difficult labor & then he was in the NICU for breathing problems. She held my hand for ages, long after her shift was over. Nearly 2 decades later, her presence still means everything to me.
And I’d like to recognize the many #OncTwitter nurses I have had the joy & honor of working with at @hopkinskimmel, but especially @JHHMartha, the late Margaret Gardner, & @LillieShockney. They share a common trait, which is almost magical to witness...
Read 4 tweets
Jul 24
I’m concerned that labeling #monkeypox a sexually transmitted infection (STI) will cause confusion & delay (🚂) in public response. It’s transmitted most often by direct skin-to-skin contact w/ the rash (see the whole list of ways it spreads from CDC 👇), and sex includes … 1/
plenty of direct skin-to-skin contact, but you certainly don’t need to have sex to get it. That means that we will identify cases regardless of sex/gender/age, & whether or not ppl are sexually active. We have to get this right in #SciComm headlines & opening paragraphs …/2
because most people won’t read the whole article (or 🧵). They skim. We want people to understand that common STI risk reduction advice like “wear a condom” is valuable but will still leave ppl open to a lot of risk if a partner has #monkeypox. /3
Read 7 tweets
Jul 21
For the first time in nearly a decade, we have a case of #polio in an unvaccinated adult. Per CDC, ~1 in 14 US 2y olds are currently NOT fully vaxxed & thus at risk. The US polio vaccine is safe & effective. Please verify you & your kids are up to date.
washingtonpost.com/health/new-yor…
#Polio most commonly spreads via the "fecal-oral" route which usually means not washing hands after using toilet then eating (or biting nails or, for kids, thumbsucking) but may also spread via airborne route. #WashYourHands #GetVaccinated #MedTwitter

history.com/news/vaccines-…
There are no meds to treat polio, it's all prevention. Here's info from CDC about #polio, but a better use of your time would just be to ensure you/kids are fully vaxxed. The IPV vaccine is highly effective & safe, & then you can go back to not thinking about it. #VaccinesWork
Read 7 tweets
Jun 23
#OncTwitter
NCI Pooled analysis (N=6.9K) of antiPD1/PDL1:
👉0.6% incidence CPI-related major cardiac AEs, 77% grade 3+
👉Almost half were myocarditis
👉 Twice as common w/ combos vs monotherapy & w/ CPI + targeted agent vs CPI + antiCTLA4…
#ImmunoOnc
ascopubs.org/doi/full/10.12…
#OncTwitter
👉Major cardiac AEs were mostly early events (1-2 months) occurring after median of 2 doses of CPI
👉1/4 of cases of myocarditis were fatal, all preceded by myositis 👀
👉Diverse clinical presentations so have high index of suspicion to diagnose & intervene early…
#OncTwitter
My commentary: It’s also concerning (& not surprising given what we know about pro-inflammatory metabolic syndrome as a cardiac risk fx) that markedly ⬆️ risk of MI has been reported in pts with multi-yr use of CPIs. I predict this follows a course much like HIV…
Read 6 tweets
Jun 9
Hey, #HoCoMD friends, be careful out there. This rain is crazy. Just got flash flood warning. Those of us who have lived here awhile know the history of this town, including the last tragic flash flood just 4y ago: apps.npr.org/ellicott-city/. #ECstrong
And now add a tornado warning to the flash flood warning, #HoCoMD. Done that before too in our own backyard (📸 2003). Careful out there, #EllicottCity neighbors.
Read 4 tweets

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