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Scientists debate. Should He Jiankui's draft manuscripts be released in full?

In favor: Let everyone see it, understand it, learn more about it.

Against: Unethical human subjects research, must be repressed.
Howard Bauchner, the editor of JAMA, which reviewed but rejected the manuscript, told me this was the "central quandry."

“If someone thinks it’s scientifically valid but not ethical, does that mean the study will stay in the shadows?"

technologyreview.com/s/614761/natur…
What do you think? Take the poll

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Antonio Regalado
@antonioregalado
Three people convicted in the CRISPR baby case are

We all know who He Jiankui is. But who the heck are Zhang Renli (two years) and Qin Jinzhou (18 months)??

Turns out they are the embryologists. THREAD on why that matters.
So He submitted a paper to Nature (and later JAMA) detailing the editing of human embryos which lists ten authors, nearly all from the Southern University of Science and Technology.

We got a copy of it a while back and you can see some excerpts here. technologyreview.com/f/614779/china…
So Qin Jinzhou is the first author listed on the draft manuscript and given his expertise, in embryology, you can infer he actually injected the CRISPR into the embryos.
Read 13 tweets
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Antonio Regalado
@antonioregalado
Veritas Genetics which tried to make a business offering inexpensive whole genome sequencing to consumers, is going out of business in the U.S., looks like.

Had problems including a data breach and just a lack of demand from people to know their genes.
"Veritas in July said that it had sequenced 5,000 genomes, with a goal of sequencing more than 150,000 in 2021. The company has raised more than $50 million in venture funding, according to Crunchbase."

From story last month reporting the databreach. bloomberg.com/news/articles/…
In 2017 we reported Veritas going to offer whole genome sequencing for Chinese kids, but planned offerings to that market -- predictions about baldness, musical talent -- were condemned by expert opinion here.

The china baby plan was quickly cancelled

technologyreview.com/s/608086/baby-…
Read 8 tweets
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Antonio Regalado
@antonioregalado
What do you think? Should the complete text, including scientific data, of He Jiankui's manuscripts about the CRISPR babies manuscripts become public?
further reasons that didnt fit in the poll

Pro release:
-demonstrate that direct embryo editing still not reliable
-stop next He
-defy Chinese state censorship of affair

anti release:
-research incomplete
-leave it to the authors
-no peer review
In the accompanying item, @kiranmusunuru argues why the information should be public. technologyreview.com/s/614762/crisp…
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Anyone think the earthquakes in Iran were just random acts of god?

Remember the MSM lives in a linear world still. "If this than that". They rarely focus on cyber attacks against foreign countries.

@realDonaldTrump never has to fire a shot in order to cripple Iran
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45 Days Of @ElvisCostello: a twitter megathread in anticipation of the Oct 12 release date of LOOK NOW, the new LP by Elvis Costello & The Imposters

This is either a bright idea or a brilliant mistake, but this is only, this is only, this is only the beginning...
I did something similar to this 5 years ago, in anticipation of EC & @theroots' Wise Up Ghost LP, on tumblr.

(You can still find all those posts if you look, although a lot of the YouTube links etc are now dead ends. It was 40 Days Of EC then, so for 2018 I'm upping it to 45.)
Mostly I will be going chronologically from the early years right up to the present, but it feels right to start out with Costello's 2002 song, "45."

Music Video directed by @jessebdylan


(There's an alternate "diner" version I can't find anywhere online)
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