#hydroxyurea is currently the mainstay of disease modifying therapy in #sicklecell disease and with the new landscape of therapeutics, I think we should dive in /1
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Because we don't just start people on medications for fun, without due diligence. Its science, bro. /4
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Does hydroxyurea cause cancer? Your doctor says no. But what do the data say? /16
AND THIS IS CERTAINLY TRUE FOR OUR CLINICAL PRACTICE AS WELL.../17
There are concerns about taking hydroxyurea when wanting to start a family. It's a no-no for women who are planning to start a family. But it's also documented to reduce sperm count in men. An important consideration. /20
"Hydroxyurea is the only available oral medication with proven disease-modifying benefits for the treatment of SCA... /21
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This is the crown jewel in the therapeutic crown for now...and seems like it will be for a long time to come. /fin