""Almost everybody walking around, if you were to test their blood right now, they would have some levels of antibody to the four different coronaviruses that are known," says Ann Falsey of the University of Rochester Medical Center."
"In studies, human volunteers who agreed to be experimentally inoculated with a seasonal coronavirus showed that even people with preexisting antibodies could still get infected and have symptoms."
""We work with some common cold coronaviruses. We have samples from 30 years ago... and they're not appreciably different than the ones that are circulating now," says virologist Vineet Menachery of the University of Texas Medical Branch in Galveston."
"It's also possible that, for some reason, the body's immune response to seasonal coronaviruses is just not that robust or that something about the infection itself may inhibit the body's ability to develop long-term immunity."
""If the natural infection doesn't do very well in giving you immunity, what is going to happen with the vaccine?" says Perlman. "How are we going to make sure that that vaccine not only induces a response that works for the next six months, but two to three years?""
They don't mention ADE, which may mean that a vaccine against coronavirus (SARS 2) is impossible.
"Antibody-dependent SARS coronavirus infection is mediated by antibodies against spike proteins"
sciencedirect.com/science/articl…
"Antibody-dependent SARS coronavirus infection is mediated by antibodies against spike proteins"
sciencedirect.com/science/articl…
