New preprint: Factors associated with hospitalization and critical illness among 4,103 patients with #COVID__19 in NYC
-analysis of all patients w/ Covid-19
-primary outcomes hospitalization & critical illness
-identify risk factors for adverse outcomes
-analysis of all patients w/ Covid-19
-primary outcomes hospitalization & critical illness
-identify risk factors for adverse outcomes
Among 4,103 Covid-19 patients, 1,999 (48.7%) were hospitalized, of whom 981/1,999 (49.1%) have been discharged home, and 292/1,999 (14.6%) have died or were discharged to hospice.
Of 445 patients requiring mechanical ventilation, 162/445 (36.4%) have died. Strongest hospitalization risks were age ≥75 years (OR 66.8, 95% CI, 44.7-102.6), age 65-74 (OR 10.9, 95% CI, 8.35-14.34), BMI>40 (OR 6.2, 95% CI, 4.2-9.3), and heart failure (OR 4.3 95% CI, 1.9-11.2).
Strongest critical illness risks admission oxygen saturation <88%, d-dimer>2500, ferritin >2500, & C-reactive protein (CRP) >200. For admission, most impt: age >65 and obesity; for critical illness, most important SpO2<88, then procalcitonin >0.5, troponin <0.1, age >64 & CRP>200
Conclusions: Age and comorbidities are powerful predictors of hospitalization; ⚠️however, admission oxygen impairment and markers of inflammation are most strongly associated with critical illness. medrxiv.org/content/10.110…
