MANHUNT—Britain 🇬🇧 appealed for a mystery individual infected with a highly transmissible #P1 🇧🇷 variant of #SARSCoV2 to come forward, more than two weeks after tested positive but failed to give proper contact details. Contact tracing is key!🧵 #COVID19
reuters.com/article/us-hea…
2) Britain said six cases had been detected of the “P.1” variant identified in the Brazilian city of Manaus, against which current vaccines appear to be less effective. Two were in South Gloucestershire in England and three in Scotland....
3) But a sixth individual in England, one of more than a million people tested on Feb. 12-13, had yet to be identified.
4) “If you’ve had a test on the 12th or 13th of February, (and) haven’t had your results back, please get in touch,” vaccination minister Nadhim Zahawi told Times Radio. “We are working with the postal system to try and locate them.”
5) The P.1 variant shares significant mutations with a variant first detected in South Africa known as B.1.351, which has raised similar concerns.
6) “Adam Finn told the BBC: “The evidence we have suggests that certainly the South African variant & potentially this Brazilian variant, which is somewhat similar - the vaccines we have at the moment are less effective at reducing at least mild disease and possibly transmission.
7) “One of the cases in the household in South Gloucestershire had flown from Brazil via Zurich to London, arriving on Feb. 10. All three 🏴󠁧󠁢󠁳󠁣󠁴󠁿 cases were identified as people who had flown from Brazil to Aberdeen via Paris and London and had self-isolated for the required 10 days.

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More from @DrEricDing

3 Mar
⚠️BRAZIL COVID EMERGENCY—Entire 🇧🇷 is now “Manaus”. 1700+ deaths in 24 hours, ICUs critical.

📌#P1 🇧🇷 variant is ~2x-2.5x more transmissible, says @obscovid19br

📌17 state capitals ICUs >80% full

📌”Exponential #COVID19 growth unlike any other that we have seen” @bollemdb 🧵 Image
2) Brazil is becoming an enormous Manaus" - @MiguelNicolelis
3) One group puts #P1 at an astoundingly high 2x more transmissibility.

Experiences from Manaus - the Amazonian city hit hard by the P.1 variant - suggest it could be up to twice as transmissible as earlier Covid there, the first detailed study suggests.
bbc.com/news/amp/healt…
Read 15 tweets
3 Mar
If kids under age 6 can wear masks 102 years ago in the last great pandemic, then kids today can too.

PASS IT ON. #COVID19 #MaskUp #schoolmasks Image
2) We now have major outbreaks in kids worldwide from #B117. See thread 🧵
3) This is the best example of what happens when kids don’t mask in schools....
Read 7 tweets
3 Mar
KIDS EPIDEMIC in Italy 🇮🇹—#B117 variant among Italy's infected schoolchildren and is helping to fuel a “robust” uptick in the curve of #COVID19–with higher transmission rates "among the youngest age group” of the population.
finance.yahoo.com/news/virus-var… Image
2) In recent weeks, Italy’s incidence of new cases among young people has now eclipsed incidence among the older population, a reversal of how COVID-19 afflicted residents in the first months of the pandemic.
3) Speranza announced stricter directives, contained in the first anti-pandemic decree of new Italian Premier Mario Draghi, aimed at trying to “govern this curve of contagion,” especially among school-age children.
Read 19 tweets
2 Mar
🇸🇪EXPERT HID SCHOOL OUTBREAKS & EXCESS DEATHS IN KIDS, emails reveal—A Swedish proponent of pro-natural-infection-herd who advised Tegnell was caught deliberately omitting data on school outbreaks & excess deaths, as new whistleblower emails shed light.🧵
sciencemag.org/news/2021/03/c… ImageImage
2) “Ludvigsson was one of 47 original signers of Great Barrington Declaration, a controversial document published in Oct 2020 that argued that pandemic policies should focus on protecting the vulnerable while rest of the population builds up immunity through natural infection.”
3) “Ludvigsson’s research seemed to support those ideas. In a review about children’s role in the pandemic, published in Acta Paediatrica in May 2020, he reported there had been “no major school outbreaks in Sweden,” which he attributed to “personal communication” from Tegnell.
Read 14 tweets
2 Mar
📍Bad warnings from South Africa’s CDC—#B1351 spike protein completely escapes 3 classes of therapeutic antibodies. It also exhibits “substantial to complete escape” from neutralization by convalescent plasma. It bodes Reinfection & lower vaccine efficacy.
nature.com/articles/s4159…
2) The @nicd_sa authors conclude: “These data also have implications for the effectiveness of SARS-CoV-2 vaccines, largely based on immune responses to original spike protein.”
3) “Indeed, sera from the Moderna and Pfizer-BioNTech vaccinees show significantly reduced neutralization of 501Y.V2” (#B1351)
biorxiv.org/content/10.110…
Read 9 tweets
2 Mar
WORRIED—NYC’s native variant is now concerning Fauci—it has some potential for trouble. 735 cases of #B1526 variant that emerged in New York City have now been identified in US, including 585 in the last 2 weeks—it is now found in 15 states.🧵#COVID19 bloomberg.com/news/articles/…
2)“It’s not particularly happy news,” said Michel Nussenzweig, an immunologist. “But just knowing about it is good because then we can perhaps do something about it.”
Nussenzweig said he was more worried about variant in New York than one in California.
nytimes.com/2021/02/24/hea…
3) The variant, known scientifically as B.1.526, likely started off in the Washington Heights section of Manhattan, Anthony Fauci said in a Monday news briefing. It is one of five concerning variants now being tracked nationally by health officials.
Read 14 tweets

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