Did you know—30 million doses of the Oxford-AstraZeneca are sitting idle in the US, awaiting results from its U.S. clinical trial while countries that have authorized its use beg for access. That is 30 million doses sitting idle in Ohio factory! #COVID19nytimes.com/2021/03/11/us/…
2) “Emergent BioSolutions, a company in Maryland that AstraZeneca has contracted to manufacture its vaccine in the United States, has also produced enough vaccine in Baltimore for tens of millions more doses once it is filled into vials and packaged, the official said.
3) “But although AstraZeneca’s vaccine is already authorized in more than 70 countries, according to a company spokesman, its U.S. clinical trial has not yet reported results, and the company has not applied to the Food and Drug Administration for emergency use authorization.
4) “AstraZeneca has asked the Biden administration to let it loan American doses to the EU, where it has fallen short of its original supply commitments and where the vaccination campaign has stumbled badly. The administration, for now, has denied the request, one official said.
5) I’m aware of a group being formed to help LMIC countries get vaccine access in addition to CoVAX. Im hopeful of these new initiatives. But we need vaccine access faster and sooner rather than later. Time is of the essence.
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📍VACCINES HELPING LONG COVID: Hospitalized #COVID19 patients who then got Pfizer or Oxford-AstraZeneca vaccine had decreased #LongCovid symptoms (5.6% vacc vs 14.2% not) & ⬆️ symptom resolution (23.2% vacc vs 15.4% not). Both vaccines similar benefit. 🧵 medrxiv.org/content/10.110…
2) not a trial but a prospective followup study. Still the results are compelling.
Authors concluded: “Receipt of vaccination with either an mRNA or adenoviral vector vaccine was not associated with a worsening of Long Covid symptoms, quality of life, or mental wellbeing...”
3) the study continued: “Individuals with prolonged COVID-19 symptoms should receive vaccinations as suggested by national guidance.”
Toxic attitudes—prisons are high risk for #COVID19, yet when Florida correctional officer polled his colleagues in a private Facebook group: “Will you take the COVID-19 vaccine if offered?”
Over half: “Hell no.” Only 40 of 475 respondents said yes.
VACCINE ESCAPE OF VARIANTS vs Pfizer-BioNTech & NIH-Moderna: Troubling new peer-reviewed paper shows even 2-dose recipients have serious trouble neutralizing the #B1351 🇿🇦 variant—as little as vs old SARS & bat coronavirus. #P1 is poor too. 1-dose worse. Lots of graphs🧵 #COVID19
2) First let’s cover some good news, that having 2 doses clearly MUCH MUCH better than 1 dose alone of either the Pfizer or Moderna vaccines versus neutralizing the classic #SARSCoV2 common strain. cell.com/cell/pdf/S0092…
3) Notably, notice how much stronger in neutralization the blood of people with 2 doses of either Pfizer (dark blue) or Moderna (dark red) is versus the 1 dose of each. Note the logarithmic y-axis. So the difference is even greater.
Pretty amazing that we knew about ventilation and indoor air quality back in 1896. Sad that it takes 2 full blown global pandemic since then to heed these lessons.
So much suffering preventable by adage: “The solution to pollution is dilution / ventilation”. #COVID19#Ventilate
2) CANARY IN THE COAL MINE FOR SCHOOLS: a tech savvy dad strapped a CO2 monitor to his kid to check air CO2 exposure on a school trip. Crazy high CO2 indicates poor indoor ventilation.
Ventilation & air disinfection will prevent outbreaks. #COVID19#Ventilate
3) Key thing - it’s not the CO2 per se that directly affects #Covid19 risk, but that CO2 is a proxy for ventilation. We want CO2 levels as close to fresh air of ~400, so optimally <450 parts per mil.
FYI: normal CO2 used be in <325 ppm when I was born. Now it’s 420-450 ppm in 🌎
Long Covid is serious. Britain ONS estimates that 23.6% of women with #COVID19 and 20.7% of men continued to experience symptoms five weeks after they tested positive for the virus. Nearly 10% had symptoms 12 weeks later. 🧵 #LongCovid bloomberg.com/opinion/articl…
2) the fact that 1 in 3 get rehospitalized from #COVID19 is just incredibly mind boggling.