Discover and read the best of Twitter Threads about #Gamma

Most recents (24)

#Japan is experiencing a 6th wave of #SARSCoV2 #COVID19 pandemic. This wave is primarily driven by #Omicron BA.1.1, a sublineage of BA.1 with Spike protein R346K mutation, replacing #Delta sublineage AY.29. AY.29 is a Japanese lineage of Delta. Cases of BA.2 are also reported.🧵 ImageImage
BA.2 is primarily found in international travelers in #Japan. 152 cases of BA.2 have been sequenced, 133 of which are travel related. About 50% of cases have travel history to the #Philippines and 33% to #India. The graphs (1 & 2) shows travelers imported variants to Japan. 2/n ImageImageImageImage
When travel related cases are removed from the analysis, it is primarily #Omicron BA.1.1 that is driving the present surge in #Japan. Although 19 likely community cases (no travel annotation) of BA.2 are reported in early January, no significant rise in BA.2 cases noted. 3/n Image
Read 5 tweets
Updated version of our work on #Omicron neutralization by post-variant sera & post-vaccination/vaccine breakthrough (Omicron & #Delta). Journals not very responsive these days it seems so uploaded here. Some more analysis #SARSCoV2 #COVID19 unige.ch/medecine/demed…
We did a heatmap to illustrate fold-change in reduction against seven authentic #SARSCoV2 isolates from convalescent sera of #Alpha, #Beta, #Gamma & #Delta. Nicely visible that Omicron, but also #Zeta, former #variant of interest, already quite good in immune escape Image
Post-vaccine samples & vaccine breakthrough restored immune escape of most VOCs incl. Zeta but not that of Omicron. And: Combined immunity is really good - Delta breakthrough only loss of 12.5 for Omicron & Omicron breakthrough only 1.5 loss for Delta. High titers here! Image
Read 7 tweets
Our study on neutralizing titers of 7 authentic #SARSCoV2 isolates (all #variants of concern incl. #Omicron) in a background of variant-specific-, vaccine- & vaccine break-through-immunity is uploaded here: unige.ch/medecine/demed… #COVID19 What did we find? A 🧵 1/n
We tested 104 sera/plasma against clinical isolates of early-pandemic #SARSCoV2 (pre-VOC), #Alpha, #Beta, #Gamma, #Delta, #Zeta, #Omicron. Convalescent sera/plasma were from individuals infected with pre-VOC, Alpha, Beta, Gamma or Delta, vaccinees & vaccine break-throughs 2/
Our findings: 1) convalescent samples of pre-VOC, Alpha, Beta, Gamma & Delta show significant loss for Omicron but to different degrees (post-Beta: 23-fold, post-Alpha: 56-fold) 2) Zeta had already strong immune escape (28-fold in post Alpha sera) but did not become dominant 3/
Read 8 tweets
[Thread] This is going to be a long one, but here's what we've learnt in the last 24 hours about #COVID19 and children in T&T.

Quotes are from Dr. Joanne Paul, Senior Pediatric Emergency Medicine Specialist at the EWMSC.
There have been 65 MIS-C cases in T&T since March 2020 to present. Since September 2021, when vaccines were rolled out to 12-17-year-olds, there have been no MIS-C cases in that age group.
T&T has lost 4 children (under 18) to #COVID19. Two children (both male) were aged seven, one was 13 (female) and the other was 15 (female). All had “separate, preexisting medical illnesses that made them vulnerable to COVID-19.” Both teenagers were unvaccinated.
Read 16 tweets
And this stinking pile of 💩 reveals her inner nature. She is full of resentment and envy, and took the opportunity of a horrific quintuple murder to display what she thought was wit.

Truly #evil. Utterly #disgusting. The Twitter rules prevent me saying more.
And look at THIS imbecility, where she can't understand what she did wrong, and says her remarks were in "bad taste." As if anybody on Twitter cared about taste.

Note also how she tries to cover herself with "free speech," and how her "accepting responsibility" lie All text, reads: I firmly believe in the right to freedom of
is contradicted by the whining in the tweet above.

Let's look at her "bad taste." Here's one example, which she has since deleted. "No one" @tweettruth2me tweeted : "When your political ideology means more to you than human life, you have lost your way." Lemanski's reply: Quote tweet by Lemanski: Quoted tweet from Heavy.com, all te
Read 10 tweets
#Propaganda #protip: This is an example of #IntellectualBaitAndSwitch. And a typical #gamma move.

Mr. Arthur asked " Is there any real difference between [Rittenhouse] and a child soldier on the Ethiopian border?" I replied, showing some of the differences.
Now he opines about "well-trained militia(s)", trying to imply that this has some bearing on his initial question. It's like pointing out that Ethiopian child soldiers and Rittenhouse both are members of the human species. True, but it has no bearing on the subject.
It's a typical gamma move in that gammas can't bring themselves to admit they made a mistake. Instead of acknowledging that his initial wisecrack was wrong, he has to find something else he can claim to be right about, and tell himself it cancels his previous error.
Read 4 tweets
The #gamma just couldn't leave it alone. Long thread, probably boring.

By the "deputy" I presume he is talking about the School Resource Officer. The Daily Wire story that was my source said the SRO was "investigating" under the guidance of the school administration.
He now implicitly concedes that the DW story was correct: no one outside the school was called there to investigate until Scott Smith showed up.

Well before reading this latest post, I'd formed a hypothesis. Deevoe read a story about the incident, and misunderstood it.
He somehow got the idea that multiple agencies were involved. He tweeted to that effect. Then, when I asked for his source, he reread it and realized he was wrong. Rather than admit that, he tried to bluff.
Read 16 tweets
A @Merck anunciou alguns resultados sobre o molnupinavir (MK-4482, EIDD-2801), fármaco antiviral que está sendo estudado na COVID-19. Principais achados da fase 3, com 755 participantes:
🔸Redução significativa do risco de hospitalização ou morte (48%)

Acompanha o fio! 🧶👇
🔸7,3% dos pacientes que receberam molnupiravir foram hospitalizados ou morreram até o dia 29 após a randomização (28/385), em comparação com 14,1% dos pacientes tratados com placebo (53/377).

Esses dados ainda são preliminares, e espero ver o artigo em breve com eles!
🔸Durante o Dia 29, nenhuma morte foi relatada em pacientes que receberam molnupiravir, em comparação com 8 mortes em pacientes que receberam placebo.

A Merck planeja enviar um pedido de Autorização de Uso de Emergência (EUA) @US_FDA o mais rápido possível com esses dados
Read 16 tweets
Excelente fio do @pedrocintra52 sobre os resultados de fase 3 da vacina da @CloverBiopharma (vacina de subunidade de proteína)

As eficácias contra as variantes específicas foram:
#Gamma 91.8%
#Delta 78.7%
#Mu 58.6%

Comentários abaixo 👇
Em abril, tivemos a aprovação pela @anvisa_oficial do início dos estudos aqui no Brasil!

A fase 2/3 contou com 30.000 participantes acima de 18 anos de 5 países diferentes, como Colômbia 🇨🇴, Filipinas 🇵🇭, Brasil 🇧🇷, África do Sul🇿🇦 e Bélgica🇧🇪

Desses ~30 mil participantes, metade recebeu a vacina e metade recebeu um placebo

O regime é de duas doses, intervaladas por 21 dias

No Brasil🇧🇷, cerca de 8 mil indivíduos participaram do estudo
Read 12 tweets
Thursday #covid19ab brief:
• 1522 new cases (-12 to previous days)
• 7 day trend is now 1247
• +359 active cases to 15,977
• +32 hospitalizations
• 9 new deaths
aryntoombs.github.io/brief/
The daily case numbers rise back up for Wednesday numbers restoring the day over day rising trend post Labour Day.
764 additional variant cases in Alberta:
• 1 B.1.117 #alpha
• 762 B.1.617 #delta
• 1 P.1 #gamma
Read 6 tweets
Belated Wed. #covid19ab brief:
• 1229 new cases (-63 to previous days)
• 7 day trend is now 1293
• +132 active cases to 15,618
• +45 hospitalizations to 647 (+16 to previous days)
• 18 new deaths

aryntoombs.github.io/brief/
And the daily adjustment chart with net 63 cases being removed between October 25th, 2020 and September 6th, 2021.
The 30 day waterfall chart for the trend in #covid19ab cases with whiskers for actual daily cases reported.
Read 7 tweets
Muita gente ficou surpresa com as notícias referentes a C.1.2, uma variante possível aumento na transmissão e com algum escape imunológico anunciada pelo Inst. Nacional de Doenças Transmissíveis da 🇿🇦 e da Plataforma de Inov.e Seq. de Pesq. KwaZulu-Natal

Acompanha 🧶👇
RESUMO:
🔹Variante com características preocupantes, mas que não tem circulação global
🔹Nada nos diz que vacinas não abrangeriam ela
🔹Mais um indicativo de que o vírus está se adaptando
🔹A desigualdade de distr. de 💉 no 🌎 É UM PROBLEMÃO
🔹💉E 😷pelo amor de Deus

Detalhes👇
Não é segredo, nem novidade, que a permanência desse estado de transmissão elevado, que é construído por vários fatores, (baixa cobertura 💉, falta de adesão adequada a medidas como uso de 😷, p.ex), gera um risco de vermos novas variantes surgirem
Read 29 tweets
1/ In my last post on #Gamma I said we would talk about Gamma bands. I expect this one to be slightly controversial, so at the end, let me know what you think.

In this post, I am going to teach you how to build these Gamma bands!
2/ Here is that last post on Gamma for reference.

3/Let's begin, first we need to have a basic understanding of volatility. Volatility is expressed as an annualized number that is proportional to the square root of time. What does that mean? Simply put, it's the one standard deviation move $BTC is expected to make in a year.
Read 19 tweets
#COVID19 outbreak from #Gamma variant in Gold Miners in French Guiana

24/44 infected (54.6%), and 21 symptomatic

25/44 were fully vaccinated (Pfizer)--> and 15 of those 25 were infected (60%)

but

NO clinically severe #COVID19 requiring hospitalization

wwwnc.cdc.gov/eid/article/27…
2/ Gamma variant (P1) has been shown to escape from neutralizing antibodies, but the immune system is made up of more than just humoral immunity

Studies from other variants have shown retained activity of T cell immune response

sciencedirect.com/science/articl…
3/ While the attack rate here is high among even fully vaccinated w/ mRNA vaccines, our number one goal is to prevent severe disease, hospitalizations, deaths.

With that said, as variants continue to emerge, we must monitor very closely.

Also, no mask use was reported here.
Read 4 tweets
Preprint (no revisado por pares aún) de nuestro trabajo sobre eficacia de anticuerpos neutralizantes generados por #CoronaVac (75 muestras) frente a variantes #Lambda (C37), #Gamma (P1) y #Alpha (B117) de #SARSCoV2 #Sinovac
📣medrxiv.org/content/10.110…
Variante #Gamma (preocupación) posee 11 mutaciones incluyendo algunas en el sitio de unión al receptor (RBD) asociadas con un incremento en la unión al receptor ACE2 y la infectividad (N501Y) o a la reducción en la eficacia de anticuerpos neutralizantes (K417T and E484K)
Variante #Lambda (interés) tiene un patrón único de 7 mutaciones (Δ246-252, G75V, T76I, L452Q, F490S, D614G, T859N)
Read 9 tweets
⚠️Confirmed—#DeltaVariant is by far the *most contagious** variant found to date, with a transmissibility that is ~2x faster than older strain. #P1 is 2nd fastest, says @WHO study.🧵

📍#B117 #Alpha—29% faster

📍#B1351 #Beta—25%

📍#P1 #Gamma—38%

📍#B16172 #Delta—97% #COVID19 Image
2) “Effective reproduction number of SARS-CoV-2 variants of concern/interest compared against each other, 64 countries, data until 3 June 2021”
eurosurveillance.org/content/10.280… Image
3) “Of the six variants currently designated as VOI, five were considered in our analysis and among these, only B.1.617.1 (#Kappa) and B.1.525 #Eta demonstrated a statistically significant increase in the effective reproduction number of 48% and 29%, respectively.” Image
Read 29 tweets
#LongCovid bei Kindern
Eine Zusammenfassung von Studien und Meldungen:
Klinische Merkmale, Aktivitätsniveaus und psychische Gesundheitsprobleme bei #Kindern mit LongCovid
Die bislang umfangreichste Studie über #LongCovid von 510 betroffenen #Kindern: Clinical Characteristics, Activity Levels and Mental Health Problems in #Children with Long COVID: A Survey of 510 Children
#LongCovid in England: Bericht über #Kinder die nach milden COVID-Verläufen unter #Atemnot, #Gelenkschmerzen und #Schwindel leiden. Das chronische Erschöpfungssyndrom ist bei einigen so stark, dass sie auf einen #Rollstuhl angewiesen sind #twlz #kmk
bbc.com/news/uk-englan…
Read 140 tweets
Meanwhile in #France,
"the peak of this second wave is over"

(according to the President in his Adress to the Nation):
Wait... "the peak is over" doesn´t mean "it´s back to normal"!

Confinement will only fall on December 15,
if there´s less than 5.000 new cases a day.
(today it´s ~9.000).

France is disappointed.🙁

Although they certainly can make it happen.
Meanwhile in #Switzerland:
(excess mortality of the second wave is significant)

Good news: fastest decrease in infections happens in the worst hit areas now.
Image
Read 2817 tweets
BREAKING: Tropical Storm #Wilfred has formed in the Atlantic.

This means we’ve now used all 21 names of the 2020 Atlantic hurricane season and will start using the Greek alphabet. @NOAA has predicted up to 25 storms, which would include #Alpha, #Beta, #Gamma, and #Delta.
@NOAA Meaning... Tropical Depression Twenty-Two is expected to become Tropical Storm #Alpha later today.

It will be the second ever after 2005's Tropical Storm #Alpha and likely the first Hurricane #Alpha in history.
@NOAA This tweet aged poorly.
Read 3 tweets
Decent Week. Decent Gains. Sharing my #Banknifty strategy for learning purpose. The below positions and P&L are only for reference. Actual trades were done in my account, but would not share actual P&L Screenshots here.
2. What you see here is a Double Calendar Spread modified to follow trend of the market. If the market is non-trending and stays within 0.5 sigma (standard deviation), it gains due to positive #theta or time-decay. If the market is trending on one side, #gamma gets active.
3. I should have captured initial #Greek positions also, that would have given a good perspective on how the strategy was planned. Will do it next time.
Read 9 tweets
[#Publication à découvrir] 29/05 > Etude “Towards Understanding the Origin of Cosmic-Ray #Positronsbit.ly/2MBRAh9 publiée dans Physical Review Letters #LaMethSci
.@parizot > à la fin du XIXe s, on découvre tout un pan de la réalité physique ignoré précédemment : le monde subatomique, ainsi qu'un certain nombre de particules nouvelles comme les RX, les R gamma, les particules alpha, etc. #LaMethSci
.@parizot > ce sont des noyaux d'atomes qui se baladent dans la galaxie. Suivant leur type, on a différents types de rayons cosmiques. Les + courants sont les noyaux d'H, puis He, C, Fe, et bcp moins fréquemment des particules lourdes comme l'uranium #LaMethSci
Read 25 tweets
#Straddles vs #Strangles ( Sell only )

These are the most common #Options strategies when one would start with #OptionsTrading.

Let’s understand from a broader perspective what’s the difference between these two.
Would not like to discuss the construction difference between them if you don’t know stop trading #options

#Straddles

You get higher premium so pnl would be higher compared to #strangles

But from where are you getting higher premiums is that your selling 0.5 #delta.
So probability of one going wrong is always 50% so to simply put one side is goin to get stuck in a #straddle but then market tends to #flucuate a lot so there is always the case of #meanreversion if you have selected the #strike rightly.
Read 14 tweets
#Option #Greeks Simplified

#Options are definitely more complicated than equity or futures.

Their prices don’t just go up and down.

They also fluctuate based on things like #time, #implied #volatility and #underlying stock movements.
#Options #Greeks Are Simply Mathematical Shortforms

Most of you would remember from school that mathematical formulas sometimes were #Greek letters like Pi and #Delta. The same is true for options.

Don’t let them overwhelm you or scare you.
They’re simply #mathematical words to explain some very basic principles.

#Greeks Describe the Behavior of #Individual #Options

Each #greek can help predict how it will behave under different circumstances and how options prices would change.
Read 22 tweets

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