#WeekendLecture #Aneurysms & #SAH #NCCT is the 1st #diagnostic test
If CT is (-), next step should be lumbar puncture
If imaged on 3rd-gen CT, < 6h of onset in a neurologically intact pt & interpreted as normal by a neurorx, SAH is r/o and no further investigations are necessary
#Pregnancy and #puerperium confer an ⬆️ risk for ischemic as well as hemorrhagic stroke, with incidence rates being 3-fold higher as compared with nonpregnant women
Radiological construct: small (2–10 mm diameter) round or ovoid #hypointense foci with associated #blooming with enhanced visibility on #MRI sequences sensitive to #susceptibility effects
#WeekendLecture #ESUS
In most studies ~25% of ischemic stroke are classified as #cryptogenic
In 2014 the Embolic Stroke of Undetermined Source clinical construct was introduced, as a subset from cryptogenics
Criteria & diagnostic assessment were proposed
Although a long list of causes was described, covert AF was conceived as perhaps the most important underlying mechanism
It was hypothesized that oral #anticoagulation may⏬ the risk of stroke recurence in #ESUS
A systematic review in 2017 (from several authors of the pivotal paper) showed:
👉Frequency: 17% (9-25%) of IS
👉Mean age: 65
👉Recurrence: 4.5% per year
👉Younger, lower freq of vascular RFs and milder stroke vs non-ESUS IS