Mia Malan Profile picture
10 Dec, 18 tweets, 12 min read
Update on #Omicron in SA via @Dr_Groome from @nicd_sa (presented @ Fri's @heatlhza press briefing):

[Thread]

1. The 7 day moving average of new #COVID19 cases = increased 40-fold between 16 Nov (332) + 8 Dec (13,237)
2. This increase is much steeper than in any previous wave
2. @Dr_Groome:
1. The increase in new #COVID19 cases = mostly driven by Gauteng, where the #Omicron outbreak started
2. Left graph = absolute nr of cases, right graph = incidence (new cases), accounted for population size = starting to see increases in other provinces too
3. What do new #COVID19 cases look like by age?
1. Early on in the #Omicron wave we saw more cases in younger age groups
2. Currently, the incidence is highest in the 20-39 year and 40-59 year group, followed by the 60+ year group
4. @Dr_Groome:
There has been a dramatic increase in the test positivity rate (the % of tests that come out positive) - this increase is steeper than in any previous wave:
- Between 14 + 28 Nov the + rate increased from 2.5% to 24.9%
- Yesterday (Thu), the + rate was: 29.8%
5. @Dr_Groome:
1. This is how positivity test rates are distributed across SA (red = over 30%)
2. See how the red is concentrated in the north of SA in Gauteng, but is now filtering to the rest of the country
6. @Dr_Groome:
1. This is a table of test positivity rates for provinces
2. Gauteng's (35%) + rate is the highest (where the #Omicron outbreak in SA started), followed by Northwest, MP and Limpopo (all 3 = neighboring provinces of GP)
7. Which SA provinces have officially entered a 4th wave?
@Dr_Groome:
1. Gauteng
2. Northwest
3. Mpumalanga
8. What's happening with reproductive (R) numbers? (This is how many other people 1 infected person will infect):
1. Nationally our R nr = 2.55 (this is the highest R nr SA has seen since the start of #COVID19)
2. In Gauteng (where SA's #Omicron outbreak started) the R nr = 3.06
9. What's happening with hospitalisations?
1. The right graph shows the increase in hospitalisations in both the private and public sector
2. The left graph shows a drop off, but that is due to a delay in the reporting of cases, not an actual drop in cases
10. The left graph compares the nr of new cases (orange) with hospital admissions (grey) for all waves:

The diffs with the 4th (#Omicron) wave = admissions start later (a while after a steep increase in cases; admissions in previous waves = along with an increase in cases).
11. Early indications of #Omicron hospitalisations, based on SA data:
1. We're starting to see a disconnect between cases and hospitalisations
2. Right graph = there is a much lower % of patients getting admitted (blue) - but could be because it's still early in the wave
12. What's happening with #COVID19 deaths?
1. We haven't seen any significant increase nationally
2. We're starting to see small increases in Gauteng (where SA's #Omicron outbreak started)
13. This table shows increases in #COVID19 hospital admissions/deaths in provinces:
1. Gauteng: Increase from an average of 32.57 (for 2 weeks) to 181.07 (the average of the following 2 weeks) = 455% increase
2. Deaths in Gauteng = 68% increase
14. AGE breakdown 4 GAUTENG admissions (last 3 weeks):
1. We started off with a larger % of admissions in younger (20/below) groups, but that is now changing
2. We're now seeing the % of younger admissions decreasing + the % of admissions in older groups (slightly) increasing
15. GAUTENG admission data broken down into smaller age bands:
1. 0-5 years = a high % of admissions initially, but this has decreased from 14% of admissions to 7% of admissions over the last 3 weeks
2. 60+ admissions have increased from about 13% to just over 16%
16. @Dr_Groome:
1. This graph shows that the #COVID19 admissions we're seeing are mostly among the age groups with low vaccination rates
2. This is in line with evidence that vaccines protect people from falling severely ill with COVID (so they don't need hospitalisation)
17. What is defined as severe illness?
= People with acute respiratory distress syndrome, those needing oxygen or are admitted to ICU

Note: The data presented = early stage data, which means many beds = still available + docs are more likely to admit patients with mild disease
18. Summary:
1. The nr of new #COVID19 cases are on a sharp increase and so is the test positivity rate
2. % of younger admissions = changing (becoming a smaller % of total admissions)
3. No signals of more severe disease
4. Most hospital admissions = unvaccinated people

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More from @miamalan

12 Dec
[Thread]: Explanation:

Why will the price of #PCR #COVID19 tests in SA's private sector GO DOWN from R850/test to R500?

An agreement was reached between the Competition Commission and 2 major private labs, Ampath (Du Buisson Kramer Swart Bouwer Incorporated) + @LancetLab_ZA.
2. What are #PCR #COVID19 tests?

They're the gold standard of #COVID19 testing and are also called molecular tests. PCR tests detect genetic material of #SARSCoV2 (the COVID virus) using a lab technique called polymerase chain reaction (PCR). More:
bit.ly/31I43Lv
3. So #PCR tests are those tests for which a #HealthWorkers take a long swab and insert it into the back of your throat (oropharyngeal swab). These are the tests that you require for international traveling.
Read 8 tweets
10 Dec
[Thread] What's happening with #COVID19 vaccine boosters in SA?
Nicholas Crisp, @healthza:
1. #Pfizer boosters (3rd shots) = approved this week for 6 mnths after a 2nd shot
2. The 1st group of people = vaccinated on May 17 (start of rollout) + would qualify 4 a booster on 28 Dec
2. Nicholas Crisp, @healthza:
1. @healthza needs a recommendation from the vaccine MAC before it can start with a booster rollout
2. If approved, the rollout will start in early Jan (not on the 28 Dec when the 1st person technically qualifies)
3. Nicholas Crisp, @healthza: When will people who got jabbed with #JnJ get boosters?

1. #JnJ applied for @SAHPRA1 booster approval on Thu
2. Sahpra = review application over the weekend + make a recommendation next week
3. #JnJ + #Pfizer boosters = rolled out simultaneously
Read 4 tweets
10 Dec
[Thread] Why have 2nd #Pfizer doses for teens (12-17 yrs) been opened in SA?

Nicholas Crisp, @healthza:
Real-life data now shows the risk of myocarditis (heart inflammation) for teens after 2 shots of #Pfizer's vaccine is more or less the same as for the general population
2. Nicholas Crisp, @healthza:

Real-life data shows there is an increase in myocarditis among teens who get #COVID infection, so full vaccination (2 #Pfizer shots) will protect them against falling seriously ill with it.
3. Watch this video to learn more about the extremely low risk of heart inflammation after a #COVID19 vaccination for teens: bhekisisa.org/multimedia/202…
Read 5 tweets
10 Dec
[Thread] #JoePhaahla:
1. 67 countries have reported the #Omicron
2. There has been a 400% increase in weekly cases in KZN (week of 4 Dec compared to previous week)
2. #JoePhaahla
1. Hospital admissions increased by more than 200% (week of 4 Dec vs previous week)
2. #Omicron = dominant variant in Nov 2021 in SA (70% of specimens = Omicron, mostly Gauteng)
3. Omicron = the variant driving increase in cases in Gauteng over last 3 weeks
3. #JoePhaahla:
1. #Omicron is likely more transmissible than the #Delta variant based on the nr of increased #COVID19 cases in SA
2. #Omicron has replaced the #DeltaVariant as the dominant variant in Gauteng
Read 9 tweets
9 Dec
Martin Friede, WHO
[Thread]

1. The mRNA technology transfer hub in Africa forms part of a larger plan to make #vaccines more available in less developed countries
2. The hub forms part of the last arm of the strategy: "to initiate regional health security via vaccine production"
2. The #COVAX manufacturing taskforce has 3 workstreams that address different needs. The #mRNAHub falls under workstream 3. The aim = to improve the nr of Africa companies that can make vaccines.
3. Many issues had to be considered when setting up the hub. For instance, how they will deal with IP rights, regulatory issues (how jabs will be approved in countries), funding and how clinical trials will be conducted.
Read 12 tweets
9 Dec
BREAKING: [Thread] 1. From today, teens between 12 and 17 years are eligible for a 2nd dose of #Pfizer's #COVID19 vaccine (up until now they could only get 1 dose).

That's why some parents got sms's this morning for their teens.
2. Is the 2nd dose of #Pfizer #COVID19 vaccine for adults and teens (12 - 17 years) the same as for adults?
Yes. It's exactly the same dose.

How long after the 1st dose can teens get a 2nd dose?
42 days (this is also the same as for adults)
3. Why could teens previously only get one dose of #Pfizer's #COVID19 vaccine?

There were concerns about the risk of heart inflammation for particularly teen boys after a 2nd shot. Real-life data now shows that it's safe to take a 2nd dose for teens. bit.ly/3GnHRES
Read 4 tweets

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