#MedTwitter Hi again from your neighborhood cardiologist - This article from the UK is getting quite a lot of interest because it has worked harder in determining the incidence of COVID vaccine myocarditis after boosters. Let's think through this one. medrxiv.org/content/10.110…
#Vaccineswork #COVID19 #COVID19France #COVID19Vic #tweetiatrician The structure of their study is essentially that they looked at 42 million Brits >13 years of age and checked, based upon national medical records, whether or not they had COVID disease myocarditis, Vax myo, and...
Which dose and which vaccine it happened after (COVID disease, Moderna, Ox-Astra Zeneca, or Pfizer). They found some data that correlate with the prior Nature study at nature.com/articles/s4159… .
Difference with this newer article - they decided to extend their analysis down to 13 year olds and extend their analyses to those receiving boosters. This excellent large analysis does support previous studies that show the COVID vaccine myocarditis risk is skewed towards...
The younger men/ boys and skewed towards being after dose #2. Their newest assertion is that there is also an increased risk of around 2 per million of vaccine myocarditis after vaccine dose #3. Be careful with interpreting this because...
The authors themselves stated that the absolute and relative risks were small and they did not have the ability to adjudicate cases after #3 with cardiologists/ cardiac MRI. So, this technically goes against what @IsraelMOH found but is not the definitive answer.
Having personally witnessed the full spectrum of COVID disease in kids and adults I emphasize their conclusion: "In summary, the risk of hospital admission or death from myocarditis is greater following COVID-19 infection than following vaccination".
While we do not have direct pediatric studies confirming this (I'm working on that), adult studies say that the degree of concern you should have in regards to heart scarring depends on where that scarring came from: pubmed.ncbi.nlm.nih.gov/30445559/ and jacc.org/doi/10.1016/j.…
So, props to @UniofOxford but, it is not necessary to be terrified of myo unless your heart testing says you should be worried. Its good to talk about this in informed consent, but it is still possible to talk about vaccine risks and put them in the wider context of COVID dz.
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