WesElyMD Profile picture
Feb 2 14 tweets 9 min read
1/🧵 What is #LongCOVID⁉️
 
A disabling malady from ongoing inflammation, autoimmunity, & potential viral reservoirs (GI, brain?)
 
NEW DATA: The Lungs “light up” on special MRI Scans 3 to 9 months later in patients never hospitalized for COVID.
 
bit.ly/344Oajp
2/ These #LongCOVID pts had NORMAL CT scans but when asked to inhale Xenon, an inert gas, the MRI showed their lungs transferred gases (think oxygen) into the bloodstream abnormally. This is alarming evidence of another weird form of organ damage from COVID not visible on CXR/CT.
3/ Oxford Prof Dr. Gleeson says these patients, who were never in hospital & didn’t have acute severe illness w their COVID19, have been experiencing symptoms for a year after contracting the infection.
4/ So our lungs are damaged with COVID. What’s the importance of this in our bodies?

In #EveryDeepDrawnBreath, I tried to make it clear how amazing the cardiovascular system is.

Here is what’s getting damaged…
5/ FACTS: “Our 6 liters of blood, traveling through the body at around 4 miles an hour, exchange oxygen & CO2 using 10,000 liters of air & 8,000 liters of blood coursing through 60,000 miles of blood vessels…
6/…All of this air and blood comes into contact with the surface of our air sacs, alveoli, that if spread out would be the size of a tennis court. This maintains us as living, sentient beings.”
P. 51-52, #EDDB

This machinery is what you protect when you choose to get #Vaxxed!
7/ A new review article👇 in @Nature points out helpful observations about #LongCOVID.

It’s likely caused by some or all of these:
📍Virus continuing to live in our brains, GI, lungs, etc
📍Ongoing inflammation
📍Immune system reprogramming

go.nature.com/3gyWJWl
8/ Look at the tables. Notice how list of problems from ACUTE #COVID Dz is much shorter than the list of problems in #LongCOVID. You DO NOT want this virus, even “mild” #Omicron (hint: there is no such thing as mild COVID). All are at risk for #LongCOVID.
 
H/T @Dr_Dan_Markley
9/ My 🧵👇presents evidence than even mild COVID leads to this unsolvable (for now) problem of #LongCOVID disabling millions of wonderful people today & tomorrow.
 
Get yourself #vaccinated & #MaskUp.
 
10/ Remember that the unvaxxed are 23X more likely to be hospitalized than vaxxed, even in #Omicron wave. Also, the booster helps a ton as those vaxxed but not boosted are more likely to land in a hospital.

bit.ly/3KXKmkx
11/ Data consistently reaffirm that in omicron, vaccinated people can get infected, BUT the shots are highly effective in reducing severe illness and hospitalization.
 
To the phrase, “DO YOUR JOB,” the vaccines answer beautifully and keeps you safe.
12/ What we do NOT know is whether the rates of #LongCOVID from Omicron will be lower in those vaccinated.
 
Why is it a good bet to get the vax even if you are young and healthy?
13/ Having a reservoir of antibodies on hand when the virus enters your body, which reduces overall amount of inflammation and therefore hospitalization, is likely to help the body to stem the tide of injury and shorten recovery time.
14/fin
Let’s review: #LongCOVID

💥COVID causes injury to lung gas exchange.
💥That leads to brain problems since neurons need Oxygen.
💥The immune system fights itself after COVID, which is suboptimal.
💥💥The best way to prevent all of this is via a shot, mask, and distancing.

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with WesElyMD

WesElyMD Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @WesElyMD

Feb 1
1/🧵 Covid-19 #vaccination in American Indian & Alaska Native (AI/AN): @NEJM

The AI/AN population has the highest 1st dose & full #vaxx rates of any US racial or ethnic group.

This photo of Black Elk should remind us of true #HEROES

link: bit.ly/3KY77og Image
2/ This successful trend is especially important given AI/AN communities have been disproportionately affected by Covid-19 and by ongoing discrimination throughout the health care system.

AI/AN communities have worked to protect the health and well-being of their members by… Image
3/ …adapting community mitigation & vaccination strategies to their diverse cultures.

There are 574 federally recognized tribes located in 35 states. AI/AN lands, which are sovereign territories, extend over 100 million acres, including 44 million acres in Alaska.
Read 8 tweets
Jan 31
1/🧵 How do #COVID patients suffer after the ICU?
 
This new @JAMA_current study of 246 Dutch pts shows that 3 out of 4 people had physical problems 1 YEAR LATER plus 1 in 4 have #brainfog, depression & anxiety.
 
What do we call this?

#LongCOVID #PICS
 
bit.ly/3o4djkT
2/ The paper is also discussed in @Medscape👇: “Our study shows what an impact ICU admission has on former #COVID19 pts. Even after 1 year, half are tired or experience lack of the energy to fully resume their work," says author Marieke Zegers, PhD
 
wb.md/33U9DeF
3/ I searched this paper for well-known terms like post-intensive care syndrome #PICS, #LongCOVID & even “post-acute sequelae of COVID”#PASC
 
NADA. Zip. Zilch.

Why weren’t these names mentioned? At the very least, these pts’ disabilities are DEFINITELY PICS & underestimated btw
Read 9 tweets
Jan 25
1/🧵 Beauty in simplicity
 
For too long in life, I thought success was about climbing in the 🌎’s eyes…higher, better, farther. My physician wife & I are “new parents” to my 58 y/o brother w #DownSyndrome & he’s giving me all kinds of new understanding of what matters.

#COVID
2/ When I come home, Greg is usually hiding from me, like you see here. He thinks so beautifully, “How can I make someone else #happy in the small things in life?”

Here he is hiding in plane sight next to our dog Butter. Look at that grin!

#Recovery
3/ Hide and Seek: He taught me that if he can’t see me, I can’t see him!

At first that seems nutty, but in truth, for me to enter “into #relationship” w you, we do need to SEE EACH OTHER, right?

So who’s teaching who here?!
Read 6 tweets
Jan 21
1/🧵 WHY are Booster Rates so low⁉️

Only 1 in 4 Americans is Boosted. People get vaxxed & then bag the best protective approach.

I honestly don’t get it??

Let’s review some studies:

750k people boosted (Pfizer) showed 90% ⬇️ in death vs non-boosted.

bit.ly/33WQ2tK
2/ Another study of ~750k people showed vaccine (Pfizer) effectiveness at 7 days after 3rd dose w 93% effectiveness. WOW

BLUE (3 doses) on this graph shows WAY better protection than RED (2 doses) =
⬇️ hospitalization
⬇️ severe dz
⬇️ death

It’s clear!

bit.ly/3KuHDic
3/ And that explains clear results posted by @DrEricDing 👇 that show impressive reductions in hospital admissions…

You want to stay safe at home right??

You don’t want me as your doctor because that comes w an ICU & ventilator. Get #boosted.

Read on…
Read 6 tweets
Jan 20
1/🧵 @NEJM “Covid19 has rendered U.S. racial, ethnic & social health inequities too stark to ignore.”
 
In the face of staggering inequities in Covid morbidity & mortality, the scientific workforce must confront #StructuralRacism

TY @DrCHWilkins & authors
bit.ly/3fGHycT
2/ The 2020 U.S. Census estimated that 33% of people in the United States identify as members of racial or ethnic groups that are underrepresented in medicine but less than 6% of research faculty are members of such groups.
3/ Only 4 to 5% of participants in trials of drugs submitted for approval by the @FDA between 1997 & 2014 were from groups historically underrepresented in medicine.
Read 5 tweets
Jan 19
1/🧵 BEWARE: Mild” COVID can cause #LongCOVID‼️

@Nature study of N=147 (31 w LongCOVID) found Covid infection exerts unique & prolonged effects on our innate & adaptive immune system over 8 months later.

This may drive Long Covid.
 
go.nature.com/3ntDOQk
2/ Obviously, Acute COVID-19, caused by infection w SARS-CoV-2 is characterized by wide ranging severity from asymptomatic to fatal. Our immune response (big or little) to the virus drives the pathology that can kill us.
3/ We know that the acute infection causes pronounced immune system problems w lowering lymph cells and rising inflammatory mediators that can cause organ damage.

This is why I have to put so many people on ventilators & dialysis.

Read 8 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

:(