A study was done on about 26,000 people from >30 countries including India to assess whether alcohol drinkers had increased risk of getting affected by stroke or not. (Ref: #Neurology, Oct 11, 2022) #MedTwitter#neurotwitter
1. High level of alcohol intake was consistently associated with all stroke, ischemic stroke and intracerebral hemorrhage (ICH). 2. Moderate alcohol intake was associated with all stroke and ICH, but not ischemic stroke.
3. Low alcohol intake was associated with increased odds of stroke in India, but decreased odds of stroke in Western Europe/North America. 4. Wine consumption was associated with reduced odds of all stroke and ischemic stroke but not ICH.
5. Heavy episodic drinking pattern (>5 drinks on 1 or more days/month) was associated with all stroke, ischemic stroke and ICH
Conclusions 1. Alcohol consumption, especially moderate and heavy drinking, is associated with a higher risk of getting stroke.
2. Low alcohol intake and wine (supposedly safer options) can also lead to increased risk of brain hemorrhage (but not ischemic strokes). #MedEd#Medicine
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Resting heart rate (RHR): What is normal; health hazards of higher RHR; how to lower the RHR? 1. What is normal RHR?
Normal RHR in most adults ranges from 60-100 bpm. However, in well trained athletes, RHR is much lower, and it may be close to 40 bpm. #fitness#Heart#running
2. Is there a difference between RHR of men and women?
Yes. The average adult male RHR is 70-72 bpm, while the average for adult women is between 78 and 82 bpm. This difference is largely accounted for by the size of the heart, which is typically smaller in females than males.
3. Does the RHR vary according to the age?
In children below 10, RHR is higher. However, above 10 years of age, RHR ranges from 60-100 bpm, including in the elderly.
Heart rate during work out: What is desirable and what is unsafe? 1. For an aerobic activity to be effective, the intensity should be at least moderate. The best way to measure the intensity of workout such as running is to check the #Heart rate. This thread is about heart rate.
2. What is resting HR?
Resting HR is the HR noted on waking up after a good night's #sleep before you leave the bed. For most adults, it ranges between 60-100/min. For physically #fit people, it may be lower, and may range between 40-60/minute.
3. Which is better- lower or higher resting HR?
Lower resting HR is better. It means- heart has to contract lesser number of times to do its work. Studies have found that a HIGHER resting heart rate is linked with LOWER physical #fitness, HIGHER blood pressure and body #weight.
Commonly used drug for acidity #Ranitidine may increase the risk of #cancers
1. Ranitidine (sold under the brand name Rantac, zinetac, aciloc) is commonly used for treating acidity. Analysis of ranitidine samples has shown contamination by a chemical NDMA (nitrosodimethylamine)
2. Ranitidine use caused higher incidence of pharynx, oesophagus, stomach, liver, pancreas and colorectal cancers. Ref: Cancers (Basel), Jan 2021 3. USFDA banned ranitidine in April 2020. In India, it is not banned, but was removed from National list of essential medicines in Sep
Conclusion: It is better to avoid use of ranitidine for treating acidity due to a higher risk of gastro-intestinal cancers with its intake. #MedTwitter#Acidity
A beginner's guide to long-distance consistent running
I had no sports background & had never run before. Started #running 2 years back (6 Nov 20) at age 49. Ran 5454 km in 2021, and 3604 in 2022 until today. 9058 km in 643 days (Av 14.1 km/d). Includes 591 10k+ runs and 106 HM
Running resulted in several benefits- 22 kg #weightloss (95kg before to 73kg now). HbA1C: 4.8; normal cholesterol & BP, resting HR 45/min. Physically active and mostly pain-free despite having #ankylosingspondylitis Not on any medications.
I wish to answer some common queries, mostly based on my personal experiences (and some based on my medical knowledge) 1. Can everyone run long distances? Yes, if there is no significant medical illness, anyone can run. If you have a health issue, get clearance from your doctor.
In people without hypertension (HTN), BP is usually lower during nights (#sleep), however, in people with HTN and people aged 55 or more, BP can actually rise during sleep (reverse dipping). Studies have shown a higher incidence of heart attacks and strokes in early mornings.
In a large clinical research done in Spain in about 20,000 people, who were followed up for >6 years, people who take their BP medicines at night time had better 24-hour BP control, including at nights, as compared to those who take BP medicines in mornings.