Discover and read the best of Twitter Threads about #weight

Most recents (24)

@alpanashuklamd takes the stage at the @ColumbiaMed @WeillCornell #Obesity Conference Image
@alpanashuklamd et al examined the effect of macronutrient sequencing (carbs first vs carbs last) in ppl with diabetes, prediabetes, or gestational diabetes

This study looked at those with prediabetes:…

Among those with prediabetes, we saw significant differences in glucose, insulin, ghrelin, and GLP-1 -- all favoring the "carbohydrates-last" food order

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Read 5 tweets

Dr. Rudy Leibel of @ColumbiaMed, everyone Image
Key quote:
"The RISK of developing obesity comes from genes."

Note that he doesn't say obesity itself is caused by genes. This would be an oversimplification!

2/ Image
You've seen this graph in several versions. This is what happens when genes set a risk level and the environment selects for it, resulting in a specific phenotype

3/ Image
Read 6 tweets
Sugar consumption and its ill-effects on health

1. Recently, a review article was published that looked at the association between sugar consumption & various diseases.
Data was collected from 8601 unique research papers published earlier on this topic.…
2. Highest versus lowest dietary sugar consumption was associated with increased body #weight (sugar sweetened beverages) & fat accumulation in liver.
*Each serving/week increment of sugar sweetened beverage consumption was associated with a 4% higher risk of gout.
3. Each 250 mL/day increment of sugar sweetened beverage consumption was associated with a 17% higher risk of coronary heart disease & 4% higher risk of all cause death.
Every 25 g/day increment of fructose consumption was associated with a 22% higher risk of pancreatic #Cancer.
Read 5 tweets
1. Sleep 7-8 hours/night
2. Exercise 30-40 min/day
3. Avoid stress/tension
4. Eat healthy- avoid sugar/ultraprocessed foods
5. Have early dinner (6-7 PM)
5. Keep BP<130/80
6. Keep HbA1C<6.5 (lower the better)
7. Keep LDL cholesterol <100, total cholesterol <200, triglycerides<150
8. Get ECG, Echo, TMT done once a year
9. Take periodic vacations and breaks
10. When unwell/tired/suffering from fever/flu- avoid workouts/exercise
11. Runners: #Run slower and lesser (don't go for PB/ultramarathons)
12. Gymmers: Lift lesser #weight, do more repetitions
13. Consult #nutritionist if you wish to take food supplements.
14. Don't chase "six packs" or "size zero figure", as they are not healthy
15. Don't smoke
16. Avoid alcohol
17. Everyone should learn CPR
18. If non-drug measures fail, please take medicines for BP/sugar control.
Read 3 tweets
#obesity brain atrophy is similar to #Alzheimers disease (AD)

1. Obesity is linked to multiple health hazards such as diabetes, hypertension, cancer, heart attack and stroke.
Recently, excess #weight has also been related to brain atrophy and cognitive decline.
2. Obesity-related grey matter atrophy resembles that of AD as per a recent research.
Cortical thickness was reduced in frontal, parietal & temporal regions.
The similarity in brain atrophy between AD & obesity was the highest in the right temporal and left prefrontal cortex.
3. Conclusion
Excess weight management could lead to improved health outcomes, slow down cognitive decline in aging, and lower the risk for Alzheimer's disease…
Read 3 tweets
I usually tweet about #obesity but since I recently had a pt with type 2 #diabetes go from 100 units/d insulin to 0 with tirzepatide, this is a good time to review #insulin management when you start a GLP1 / GIP

#endocrine #endocrinology #research #clinicians
SURPASS-5: tirzepatide + basal insulin vs. placebo

Method: If baseline A1c<8, ⬇️long acting insulin dose by 20% at start of study

Result: At end of study, insulin was ⬇️11% for 15-mg tirzepatide group vs. ⬆️75% for placebo…

2/ Image
SUSTAIN-5: semaglutide 1.0 + basal insulin vs. placebo

Method: If baseline A1c<8, ⬇️long acting insulin dose by 20% at start of study

Result: At end of study, insulin ⬇️15% for 1-mg semaglutide group vs. ⬇️4% for placebo…

3/ Image
Read 7 tweets
1/14 #Men and #women experience disease differently. This is reminiscent of #SyndromeX and other chronic disease like #MECFS, #slow #virus manifestations, and even #LongCovid and post-acute sequelae of #SARSCoV2.

A thread summary article 🧵….
2/14 "#Women are up to 75 per cent more likely to experience #adverse #reactions to #prescription #drugs than #men because of a range of differences in #traits between the #sexes, according to a new study from The #Australian #National #University (#ANU)."
3/14 "The researchers believe more should be done to take this into account when treating #diseases."
Read 16 tweets
A very interesting thread on @Reddit with @Walgreens employees and others discussing the rules made by @LillyPad to only place through prescriptions with the diagnosis of #diabetes - #Mounjaro is NOT YET indicated by the @US_FDA for #obesity as a diagnosis
The stigma for #obesity is directed at those with the disease. Unfortunately our society perceives that obesity is a “second class” disease and should be treated as such. Here @Walgreens employees are admitting to discriminating against patients 1/
The patients have been prescribed #Mounjaro “off-label” for the treatment of #obesity (because this medication has been shown to result in the highest weight loss of any medication at 22% total body weight lost) 2/
Read 4 tweets
Food myth busted: Potato is not bad for diabetics

1. Potato has got a bad name, and diabetics are advised to avoid it because of its high glycemic index. However, findings of a recent research busts this myth.

#nutrition #healthyfood #diet #MedTwitter #diabetes #weightloss
2. This was an 8-week randomized, controlled feeding study comparing Potato and Bean diets (50-55% carbohydrate, 30-35% fat, 15-20% protein).
Thirty-six participants (18-60 years, BMI: 25-40 kg/m2) with insulin resistance were enrolled.
3. Among study completers, HOMA-Insulin resistance in the bean group showed an average decrease of 1.4 from baseline (P = .02 ); a similar decrease of 1.3 occurred in the potato group (P < .05) with no significant difference between the two diets.
Read 5 tweets
Though not its intention, this study from #OW2022 illustrated the concepts of satiation vs satiety very well

Colloquially we use these terms interchangeable

But they are technically different

#obesity #science #research #physiology #pathophysiology

1/ Image
Satiation is the feeling of fullness WITHIN a meal while satiety is the feeling of fullness IN BETWEEN meals

Even though current meds like GLP1s seem to affect both, it’s an impt distinction especially when some peptides (eg, amylin)
may only effect satiation (⬇️meal size) and not satiety (change meal frequency)

[btw This study was an intracerebral injection of calcitonin into male rats and calcitonin is an agonist at the amylin receptor in the ventral tegmental area]
Read 4 tweets
Milestone: My 2nd #runniversary and 10000 Km

1. Nov 6th 2020 was the most important day in my life, when I took complete control of my health & fitness. From a #workaholic, I converted to workaholic + #runaholic
Here, I present the milestones of my past 2-year #running journey
2. I completed 10,163 km of running in the past two years (6th Nov 2020 to 6th Nov 2022: 731 days), at an average of 13.9 km/day. This included 648 runs of 10k or longer, 110 runs of half marathon (21.1 km) or longer and one marathon (42.2 km).
3. I usually run at a pace of 7:15-7:30 min/km and my best pace is 5:45 to 6:00 min/km. My PB in 10 k is 57:03 min and in HM 2:04:41 hours. I cherish the #Ladakhmarathon HM the most, which I finished in 2:24:33 hours (on 11 Sep 2022).
Read 7 tweets
Intermittent #fasting and its impact on #health
What is intermittent fasting (IF)?
A variety of eating patterns in which no or few calories are consumed for prolonged time periods 
that can range from 12 hours to several days, 
on a recurring basis.
#diet #nutrition
What are the different ways of Intermittent Fasting?
1. Alternate-day fasting,
2. 5:2 or 6:1 intermittent fasting (fasting 2 days or 1 day each week),
3. Daily time-restricted feeding (Eating within 8-12 hour window and fasting during the rest of the day)
Definition of various types of intermittent fasting
Read 10 tweets
Awesome October 2021: A month of 31 half #marathons on 31 consecutive days- sharing my experience
1.Starting from 30th September, and ending on 31st October 2021, I completed 32 runs of 21.1 km or longer, with a total mileage of 817 km in 32 days (average of 25.5 km/day).
This included one Full marathon (42.2 km) on 30th October.
2.The purpose was to test my #endurance, and to see the #physical & #mental effects of long distance #running on 32 consecutive days. I present my observations here.
3. How difficult was it? In reality, it was not difficult. Once you get up and start the run, it is easy to complete. The most important is- you need 2.5 to 3.5 hours time to compete the distance. I could manage that in the mornings between 5 and 8:30 AM.
Read 11 tweets
Heart rate during work out: What is desirable and what is unsafe?
1. For an aerobic activity to be effective, the intensity should be at least moderate. The best way to measure the intensity of workout such as running is to check the #Heart rate. This thread is about heart rate.
2. What is resting HR?
Resting HR is the HR noted on waking up after a good night's #sleep before you leave the bed. For most adults, it ranges between 60-100/min. For physically #fit people, it may be lower, and may range between 40-60/minute.
3. Which is better- lower or higher resting HR?
Lower resting HR is better. It means- heart has to contract lesser number of times to do its work. Studies have found that a HIGHER resting heart rate is linked with LOWER physical #fitness, HIGHER blood pressure and body #weight.
Read 6 tweets
It's weekend and it's the end of the month. The #markets are closed.

So there is the perfect time to analyze the #momentum & relative #strength of the markets.

This information is relevant for all #investors, but especially for #trend #followers 📈📈📈


The #momentum of the markets are one of the most powerful forces in the evolution of the #asset #prices.

The #reversion to the mean is the opposite force, which is equally powerful. Momentum works on a short and medium term (up to 3 to 5 years).
There is a ton of academic research related to the momentum and the benefits of using it and relative strength. But presenting it this is not the purpose of this #thread.

Relative strength is actually a comparison between the #momentum of two or more #markets.
Read 35 tweets
@MondayNightIBD @DCharabaty @abbvie @JanssenUS @TakedaPharma 1/ #IBDPoll1️⃣ 30M non-smoker w stricturing #Crohns ileocolitis dx 1 year ago is now s/p ileocecal resection due to refractory symptoms despite adalimumab.

What would you recommend post-surgery? #MondayNightIBD

🔦= C-scope
🔥= Active disease
Metronid= Metronidazole
@MondayNightIBD @DCharabaty @abbvie @JanssenUS @TakedaPharma 2/ #IBDPoll2️⃣ The pt was started on IFX 4 weeks post-op, but now presents @ 8 weeks post op w #Diarrhea 6-8 loose BM/day, no abdo pain, no blood. Stool Cdiff & Cx negative. FCP, CRP nml,

What’s next ? #MondayNightIBD
@MondayNightIBD @DCharabaty @abbvie @JanssenUS @TakedaPharma 3/ #IBDPoll3️⃣ Pt is dx w #BAD w 7C4 level 80ng/mL, & started cholestyramine. Now presents w abdo pain, MRE multiple SB #Strictures ➡️Sx complicated by leaks & more✂️. Now w foul smelling diarrhea, Wt loss, dry mouth, orthostasis. CLN & Stool studies nml.
What’s next?
Read 5 tweets
Joined: Mar 1, 2021.
Ht/#weight: 170cm/89.5kg
Eltroxin 50mcg
Nexprofast 40 mg - 2x/d
ISTAMET 50/1000 - 2x/d
ActaPro 100 - 3x/d
Rosuvas 10 - 1x/d
Gaviscon syrup - 2x/d
PPBS: 165-180
Grade 2 #fattyliver
GERD, Abdominal pain, tiredness, weakness.…
Mar 2,2021
Rosuvas 10 - STOPPED INR 16/day or INR 480/Month
Mar 5, 2021
B/F switched to #LCHF other two meals regular
Morning istamet 50/1000 replaced with glycomet 1g
Price diff b/w stamet & Glycomet ~ INR 22/d = INR 660/Mo

Total savings on medications: INR 1140/Mo.
Read 9 tweets
9 causes of low sperm count/quality you should know

1. Infections
2. Varicocele
3. Heat & Stress
4. Drugs
5. Being too fat
6. Hormones
7. Other medical issues
8. Alcohol & smoking
9. Chemicals

A thread 🧵

Please RT for awareness
Low sperm count or #oligospermia means the semen a man ejaculates during an orgasm contains fewer sperm than normal. Medically, it means having less than 15 million sperm in 1ml of your semen.

If there's no sperm at all in your semen, it is called #azoospermia.
Having low sperm count significantly lowers your chances of being able to impregnate a woman.

Many families have been torn apart because of the resulting infertility.

Unfortunately, in some cases, people erroneously think the cause of the infertility is the woman.
Read 16 tweets
The devil is in the 'detailed' #drug history #clinical
22 yr male, underweight
Fatigue, appetite loss
Liver test AST 400 ALT 600
Viruses negative
Liver #biopsy 👇Severe #fatty #liver #disease, Mallory Denk++
#livertwitter #pathology #MedTwitter #MedStudentTwitter Image
The culprit 👇#Ayurveda #medicine
#Ayurvedic jam with butter, honey, milk as base given for premarital #weight gain! 3 months after stopping, liver tests normal
Consider #drug induced fatty liver in #patients. Not everyone is #metabolic #syndrome
#pseudoscience #Nash #nafld Image
Common drugs causing fatty liver
Steroids, Valproate
Inj Tetracycline
Rare - methotrexate, chemodrugs irinotecan, 5FU, tamoxifen
Also important is Amiodarone
Herbals with #Margosa oil too
Remember #alternative meds rich in fats are important causes too.
Read 3 tweets
Would you like some #greentea #extract #Herbal #supplements drink for #weightloss?
Good, you can enjoy your #weightlosstransformation 6-ft-under. Here is what #greentea extract does👉liver biopsy #marked regions = what is left of liver
#livertwitter #pathology #LiverPath ImageImage
1. Check/declare your supplements.
2. Be wary of #nutrition and #weight management #quacks
3. Want #loseweightfast? - sweat it out, dont sweat your liver out.
4. #STAY away - multilevel marketing #FRAUDS
More 👉
#MedTwitter #MedStudents #media #healthy
Never forget the #sexist, #outrageous, #PANIC inducing #advertisement that #pseudoscience #Ayurveda and #Homeopathy uses as #fishing #bait on unassuming persons
NO '#faster way to lose weight' - its a #myth
#health #education #MedEd #publichealth #shortstories #girls ImageImage
Read 3 tweets
Very disappointing #obesity strategy from the UK government @BorisJohnson.Disappointing because it is:1)#weight biased 2)non #evidence-based and subsequently unlikely to be effective 3)ignores people with #obesity ie ignores treatment of obesity #obsmuk 👇…
2/The underlying issue that needs to be tackled in any #obesity strategy is bias and discrimination against people with obesity and the attached stigma. Weight bias and stigma hinder the efforts to initiate a proper strategy to fight obesity. #obsmuk #actonobesitynow
3/The measures that the UK government introduced are non evidence based. There is no evidence that the strategies the government introduced will prevent #obesity or treat #obesity. Subsequently, likely waste of time and money.
Read 9 tweets
for those who missed my @aberdeen_ucu talk today on #sugar, #breakfast, #health & #appetite, a wee thread on the fascinating properties of sugar...
full talk (poor sound qual) can be found here:

#sugar is demonised in the media, literally described as "evil". myths include: its addictive, causes cravings, makes you hungry, makes you overeat, makes you gain weight.

current #publichealth guidelines target reducing sugar
#breakfast is touted the "most important" meal of the day. what does "important" mean?

breakfast is the highest #sugar meal of the day so a good meal to target to reduce total sugar.

breakfast = complex to define, but broadly breaks the overnight fast (break-fast) 3/21
Read 24 tweets
For all those who argue as nauseum about #lowcarb !! I'm a doctor and I'm not an idiot to tell people to stay off medicines and focus on inner immunity and health. All my life I struggled with a hypocaloric high carb diet. That's why I feel deeply about this whole topic. #health
I was a plump child and was always told to eat less and exercise more. I was always hungry. I grew up to a fat teen with a terrible body image. It drives me up the wall to see people unnecessarily arguing about the so called balanced diet. I tried all gimmicks : Alas
Thank God that I came across #IntermittentFasting and #lowcarb. It's never about #weight. It's about #Health. #weightloss and a #positiveattitude is the by product.
Thank you to all those who have been a part. I'm 3 years menopausal now. And pretty much fit for my age. #fit
Read 6 tweets
"Reclaiming monetary Sovereignty and sustainable prosperity in #Africa" starts now with @FadhelKaboub at the launch of the international conference "The quest for economic and Monetary sovereignty in the 21st century in Africa. @Mon_Sovereignty…
@FadhelKaboub @Mon_Sovereignty Follow the LIVE in the link below 👇🏿👇🏿…
@FadhelKaboub @Mon_Sovereignty @FadhelKaboub : In Tunisia, in the 70s two interesting patterns were unleashed with the opening of he economy.
☝🏼☝🏼Increase in trade deficit
☝🏼☝🏼increase of external debt
@Mon_Sovereignty #Tunisia
Read 11 tweets

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