Young woman who would lose eyesight in left eye each time she took hot water bath
1. 25-yr old woman consulted me with complaints of losing #vision in left eye after hot water bath. This had occurred 8 times in the past one month. Vision would get restored in a few hours on own.
2. Short-duration loss of #eye sight had occurred last Winter too, but she ignored them.
Last week, she was taken for an #ophthalmological examination after one such episode, and no abnormality was detected.
Her family members thought she was making up her symptoms. #MedTwitter
3. She requested her husband to take her for further expert medical opinion, which he refused.
But the woman was convinced that her symptoms were for real, as she had definite loss of vision in left eye after hot water bath.
So, here she was in my OPD, against her family's wish
4. On detailed enquiry, she also reported similar loss of vision in left eye after her Zumba sessions. Again the loss of vision would last a few hours after the exercise, and return to normal in a few hours. She reported occasional "pins and needles" sensations in hands and feet.
5. By now, it was clear what the woman was suffering from. This phenomena had been described by an #Ophthalmologist 132 years ago.
I ordered for two investigations to confirm my suspicion- VEP (visual evoked potential) studies and #MRI (#brain & spine). #NeuroTwitter
6. She returned the next day with reports and the diagnosis was confirmed.
VEP studies showed features of optic nerve dysfunction and MRI was diagnostic for multiple sclerosis (MS).
I discussed the treatment plan with her (& husband). #MultipleSclerosis
7. Transient loss of vision on exposure to heat is referred to as #Uhthoff's phenomenon (eponym taken from the surname of the Ophthalmologist, who first reported it in 1890).
Patients with MS are advised to avoid exposure to heat in order to prevent worsening of symptoms of MS.
8. Take home message
*Short duration loss of vision after hot water bath or exposure to hot sun in a young person (aged 15-60 years) could be a symptom of multiple sclerosis.
*Careful clinical assessment and investigations can establish the diagnosis.
• • •
Missing some Tweet in this thread? You can try to
force a refresh
6-yr old to me: "Doctor, I have grade 4 cancer and will live only for 6 more months, don't tell my parents about this" 1. It was another busy OPD, when a young couple walked in. They had a request "Manu is waiting outside. He has cancer, but we haven't disclosed that to him+
2. Please see him and advise your treatment, and don't share the diagnosis to him". I nodded my head, accepting their request.
Manu, on a wheelchair, was brought in. He was referred by his #oncologist for management of seizures.
He had a smile, appeared confident & smart.
3. On reviewing history and medical records- Manu had been diagnosed with glioblastoma multiforme grade 4 in left side of brain, due to which he had paralysis of right hand and leg. He had been operated, and was on chemotherapy. Seizures were due to brain cancer. #MedTwitter
Taking 6000-9000 steps/day reduces the risk of cardiovascular disease (CVD) in older adults aged 60 or more
1. In a recent study, taking 6000 to 9000 steps per day was associated with a 40% to 50% lower risk of CVD, compared with taking 2000 steps per day. #walking#Medtwitter
2. There was a dose response noted between CVD risk and number of steps per day.
As the number of steps per day increased, the risk of CVD too decreased.
3. Compared with those who got the fewest steps/d (median 1811), the risk of CVD was 20% lower in those in quartile 2 (median of 3823 steps/day); 38% lower in quartile 3 (median of 5520 steps per day) and 49% lower in quartile 4 who walked the most ( median of 9259 steps/day).
1. People are opting for diet soft drinks in place of regular soft drinks, assuming that they are free of sugar, contain zero calories and hence are healthier & safer. But research shows evidence to the contrary. #MedTwitter#HealthyFood
2a. In two studies conducted in US & Europe, individuals who consumed diet soft drinks had higher prevalence of metabolic syndrome than non-consumers.
Diet soft drink intake positively correlated with waist circumference and fasting plasma glucose in both studies.
Sharing experiences of my #fitness journey
Could be of help to those who have planned to start theirs in 2023 1. My earlier self:Weighed 100 kg, could walk 5 km with great difficulty
Negatives: Worked 16-17 hours/day; slept 4-5 hours; overeating, indulged in junk food and sweets
2. Fitness journey started on Nov 6th 2020. Initially walked 5 km, gradually increased to 10 km over 4-6 weeks, then, slow jogged and finally started running. Focused on distance and time on feet and not pace. Also wanted to keep HR low and feel comfortable. #running#Health
3. Running stats: 2021- Avg running 15 km/day, 339 runs of 10 k or more, 69 half marathons (HMs) and 1 full marathon. 2022- Avg running 12.6 km/day; 304 runs of 10 k or more, 43 HMs
Finished Ladakh marathon in 2:24 hours
Best timings: 10 Km in 51:11 min; HM in 2 hours
#Kiwifruit found effective in #constipation 1. Constipation is a common problem and drug treatments do not work in many.
In a recent trial, efficacy of kiwifruit was tested in patients with functional constipation (FC) & constipation-predominant irritable bowel syndrome (IBS-C)
2. Participants were randomly assigned to consume either two ripe green kiwifruit without the skins, or 7.5 g of #psyllium per day for 4 weeks.
Psyllium (OTC) is considered a first-line treatment for both the constipation conditions with which participants were diagnosed.
3. At the end of the 4-week treatment periods, the people with functional constipation who ate kiwifruit demonstrated an average increase of 1.53 bowel movements per week, a statistically significant increase.
Those with IBS-C demonstrated an increase of 1.73 bowel movements.
A teenager whose unusual #disease forced him to live a #lonely life
1. Sam was a bubbly kid until the age of 8, when his parents noted that he would blink his eyes on an off. This did not trouble Sam, however, he was taken for an eye check up, which didn't show any abnormality.
2. Two years later, he started shrugging his shoulder and would occasionally hop on one leg. This would repeat 5-6 times in a day. Sam had no control on these movements. Again, this did not bother Sam but his parents were perturbed. They thought Sam is being naughty. #MedTwitter
3. By age 12, Sam started to make some unusual sounds, as if he is clearing his throat or grunting. Sam had no control on these sounds too.
His friends had started making fun of him. He could suppress them for a few minutes, however, after that, movements & sounds would return.