Can resistance training counteract the adverse effects of androgen deprivation therapy?

A thread 🧵👇

#resistancetraining #prostatecancer #ADT
Prostate cancer is one of the most common types of cancer. An effective treatment is androgen deprivation therapy (ADT), which lowers testosterone levels to castration levels. However, such low testosterone levels tend to result in a loss of muscle mass and strength.

2/
Our study investigated the effect of resistance training with or without protein supplementation on muscle mass and strength in prostate cancer patients undergoing ADT.

3/
Subjects were divided into 3 groups:
1) ADT control group
2) ADT + resistance training
3) ADT + resistance training + protein supplementation

4/
Resistance training was a 20-week supervised program (2 sessions per week). Protein supplementation was 31 g whey protein provided after each training session and every night before sleep.

5/
Muscle mass was determined with CT (quadriceps cross-sectional area) and muscle strength with 1 repetition maximum tests.

6/
As expected, muscle mass (-2%) and strength (-5%) decreased in the ADT control group. Resistance training completely counteracted the loss and even increased muscle mass (+3%) and strength (+15%), with no additional effect of protein supplementation.

7/
These findings suggest that muscle mass and strength gains can be made even with very low testosterone levels.

8/
In conclusion, resistance training can overcome the adverse side effects of ADT on muscle mass and strength with advanced prostate cancer.

Our study:
pubmed.ncbi.nlm.nih.gov/36534950/

Did you find this useful? Please help promote the first tweet of the thread:

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Jorn Trommelen, PhD

Jorn Trommelen, PhD Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @JornTrommelen

Feb 22
Can alcohol consumption affect muscle growth?

A thread 🧵👇

#alcohol #muscleproteinsynthesis #recovery Image
Exercise and protein ingestion are the main factors that stimulate muscle protein synthesis (the main process driving muscle adaptations such as growth).

2/ Image
It has been reported that athletes are more likely to consume excessive amounts of alcohol, especially as part of binge-drinking practices in team sports. Can these practices affect muscle protein synthesis?

3/ Image
Read 8 tweets
Feb 9
Do older people need more protein following exercise?

A thread 🧵👇

#aging #healthyaging #muscle
Muscle growth occurs when muscle protein synthesis exceeds muscle protein breakdown. Resistance exercise stimulates both muscle protein synthesis and breakdown. Ingestion of protein further increases muscle protein synthesis and is needed to achieve positive protein net balance.
In young adults, 20 g of high-quality protein seems optimal to stimulate post-exercise muscle protein synthesis. However, is this also true for older adults?

3/
Read 7 tweets
Jan 7
At which age do we start to lose muscle mass?

A thread 🧵👇

#ageing #muscle #sarcopenia
Aging is associated with the loss of muscle mass. This phenomenon is also known as sarcopenia. Around what age does this start to occur?

2/
This study investigated the influence of age on muscle mass in a large sample of adults. Skeletal muscle mass was measured with a whole-body MRI for 468 adults of 18-88 years old. People that were bedridden, had physical disabilities, or had chronic illnesses were excluded.

3/
Read 7 tweets
Dec 13, 2022
How to improve your endurance capacity for increased health and performance?

Here’s a thread of some of our endurance exercise infographics 🧵👇

#endurance #performance #VO2max
Aerobic capacity is defined as the maximal rate of oxygen consumption (VO2max). A large improvement in aerobic capacity can already be achieved during an intense 10-week training program.

2/
Non-responders to exercise probably don’t exist. However, there are people that need a lot more exercise volume to obtain the same fitness benefits compared to others.

3/
Read 8 tweets
Nov 18, 2022
Does the order of drinking wine and beer matter for hangover severity?

A thread 🧵👇

#beer #wine #hangover
It is well established that drinking too much alcohol will result in a hangover. It is commonly suggested that the hangover will be less if you stick to one type of alcoholic drink, rather than drinking different types of drinks.

2/
In addition, there are several sayings such as: “Beer before wine and you’ll feel fine; wine before beer and you’ll feel queer”. This suggests that the order of drinks may impact the hangover.

3/
Read 9 tweets
Nov 17, 2022
Can the Mediterranean diet reduce heart problems?

A thread 🧵👇

#mediterranean #nuts #oliveoil Image
Mediterranean countries have lower cardiovascular mortality rates compared to northern Europe and the United States. It is often suggested that this is at least partly due to the Mediterranean diet.

2/ Image
The Mediterranean diet includes high intake of olive oil, fruit, nuts, vegetables, and cereals; a moderate intake of fish and poultry. In addition, it has a low intake of dairy products, red meat, processed meats, and sweets; and moderate wine consumption.

3/ Image
Read 10 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us on Twitter!

:(