Jorn Trommelen, PhD Profile picture
Assistant professor. Muscle Metabolism.
Jul 12 9 tweets 4 min read
Protein distribution: beneficial, detrimental, or inconsequential?

Our response to commentary.

❌Not eating =/= fasted state
🥩Protein amount vs protein distribution
✅Practical recommendations

A 9-part thread. 🧵👇 Image The concept of protein distribution suggests that how you distribute your meals throughout 24 hours strongly impacts your overall anabolism.

There are contrasting lines of thought of what meal frequency is preferred for various health or athletic outcomes.

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Dec 19, 2023 10 tweets 4 min read
Our new work:
No upper limit to the anabolic response to protein ingestion?

Challenges current views on:
1⃣Dose-response relationship
2⃣"Excessive" protein getting oxidized
3⃣Protein distribution
4⃣MUCH more!

Paper:


1/10 🧵 cell.com/cell-reports-m…
Image It is generally accepted that a single bolus of 20 g protein results in a near-max stimulation of muscle protein synthesis in healthy young adults.

Excessive protein is thought to be oxidized.

This is the basis for the recommendation to distribute daily protein intake.

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Mar 3, 2023 9 tweets 3 min read
Does the ketogenic diet increase fat loss?

A thread 🧵👇

#keto #dieting #fatloss The ketogenic diet restricts carbohydrates with the purpose of lowering insulin levels. Insulin is a hormone that is involved in fat metabolism. Therefore, some suggest that a ketogenic diet is very effective for fat loss.

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Mar 1, 2023 9 tweets 4 min read
Our new paper:
Pre-sleep Protein Ingestion Increases Mitochondrial Protein Synthesis Rates During Overnight Recovery from Endurance Exercise: A Randomized Controlled Trial

Open access link:
link.springer.com/article/10.100…

A thread 🧵👇

#protein #casein #whey Image We have previously shown that pre-sleep protein ingestion improves overnight myofibrillar protein synthesis.

In addition, we have shown that long-term pre-sleep protein supplementation improves muscle mass and strength gains.

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Feb 23, 2023 9 tweets 3 min read
Can resistance training counteract the adverse effects of androgen deprivation therapy?

A thread 🧵👇

#resistancetraining #prostatecancer #ADT Prostate cancer is one of the most common types of cancer. An effective treatment is androgen deprivation therapy (ADT), which lowers testosterone levels to castration levels. However, such low testosterone levels tend to result in a loss of muscle mass and strength.

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Feb 22, 2023 8 tweets 3 min read
Can alcohol consumption affect muscle growth?

A thread 🧵👇

#alcohol #muscleproteinsynthesis #recovery Image Exercise and protein ingestion are the main factors that stimulate muscle protein synthesis (the main process driving muscle adaptations such as growth).

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Feb 9, 2023 7 tweets 3 min read
Do older people need more protein following exercise?

A thread 🧵👇

#aging #healthyaging #muscle Muscle growth occurs when muscle protein synthesis exceeds muscle protein breakdown. Resistance exercise stimulates both muscle protein synthesis and breakdown. Ingestion of protein further increases muscle protein synthesis and is needed to achieve positive protein net balance.
Jan 7, 2023 7 tweets 3 min read
At which age do we start to lose muscle mass?

A thread 🧵👇

#ageing #muscle #sarcopenia Aging is associated with the loss of muscle mass. This phenomenon is also known as sarcopenia. Around what age does this start to occur?

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Dec 13, 2022 8 tweets 4 min read
How to improve your endurance capacity for increased health and performance?

Here’s a thread of some of our endurance exercise infographics 🧵👇

#endurance #performance #VO2max Aerobic capacity is defined as the maximal rate of oxygen consumption (VO2max). A large improvement in aerobic capacity can already be achieved during an intense 10-week training program.

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Nov 18, 2022 9 tweets 4 min read
Does the order of drinking wine and beer matter for hangover severity?

A thread 🧵👇

#beer #wine #hangover It is well established that drinking too much alcohol will result in a hangover. It is commonly suggested that the hangover will be less if you stick to one type of alcoholic drink, rather than drinking different types of drinks.

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Nov 17, 2022 10 tweets 4 min read
Can the Mediterranean diet reduce heart problems?

A thread 🧵👇

#mediterranean #nuts #oliveoil Image Mediterranean countries have lower cardiovascular mortality rates compared to northern Europe and the United States. It is often suggested that this is at least partly due to the Mediterranean diet.

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Nov 15, 2022 13 tweets 4 min read
Data extrapolation or wishful thinking?

A thread 🧵👇

#diet #training #performance Studies are typically relatively short (weeks to months). However, we often want to know what happens with longer-term adherence to interventions such as a training protocol or a diet.

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Nov 10, 2022 9 tweets 4 min read
Many supplements claim to improve body composition or exercise performance. Some supplements seem promising, while others don’t seem to do anything, and some can even be counterproductive.

Here’s a thread of some of our supplements infographics 🧵👇

#supplements #performance Image Creatine is an organic compound which is naturally present in our bodies. Creatine supplementation increases muscle creatine levels, strength and muscle mass gains during resistance training.

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Nov 8, 2022 12 tweets 4 min read
Does the ketogenic diet impair endurance training adaptations?

A thread 🧵👇

#keto #ketones #lowcarb Image The ketogenic diet is a very low carb, high fat diet, that claims to improve exercise performance by increasing the use of fat (fat oxidation) during exercise.

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Sep 23, 2022 9 tweets 3 min read
How much protein is needed after endurance exercise?

A thread 🧵👇

#protein #cycling #endurance Image Protein ingestion after exercise stimulates muscle protein synthesis (the main process regulating muscle recovery, adaptation and growth). It has been well established that protein intake improves resistance training adaptations.

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Sep 21, 2022 9 tweets 4 min read
Fructose Coingestion Does Not Accelerate Postexercise Muscle Glycogen Repletion

Our 2016 paper:
pubmed.ncbi.nlm.nih.gov/26606271/

A thread with figures.

#fructose #glucose #glycogen Image The gut absorption of the carbohydrate glucose is the limiting factor in using glucose drinks for energy during exercise (carbohydrate oxidation). Fructose is a carbohydrate that is absorbed differently in the gut than glucose. Sucrose consists out of glucose and fructose.

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Aug 17, 2022 8 tweets 3 min read
Does coffee cause dehydration?

A thread 🧵👇

#caffeine #coffee #hydration It is often suggested that coffee causes dehydration. This is because coffee contains caffeine, which has a dehydrating effect. However, coffee also contains fluid which has a hydrating effect. Therefore, it can be questioned if coffee intake really causes dehydration.

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Jul 15, 2022 10 tweets 4 min read
Can insufficient sleep increase the chance of developing a common cold?

A thread 🧵👇

#sleep #sick #insomnia Poor sleep is associated with susceptibility to acute infectious illness. In addition, sleep deprivation has been shown to negatively affect immune system functioning. Does this mean that you have a higher chance of getting sick when getting insufficient sleep?

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Apr 25, 2022 8 tweets 4 min read
Beetroot Juice Supplementation Improves High-Intensity Intermittent Type Exercise Performance in Trained Soccer Players

Our March 2017 paper:
pubmed.ncbi.nlm.nih.gov/28327503/

A thread 🧵👇

#nitrate #beetroot #soccer Image Beetroot juice has been shown to increase endurance performance because of its high nitrate content. However, can beetroot juice also increase the performance of other types of exercise?

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Mar 31, 2022 8 tweets 3 min read
Does caffeine improve exercise performance for everyone?

A thread 🧵👇

#caffeine #coffee #performance Image Caffeine has shown to improve exercise performance. Therefore, caffeine is a popular supplement among athletes.

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Sep 17, 2021 6 tweets 2 min read
Our new review:
The importance of muscle capillarization for optimizing satellite cell plasticity

Open-access link:
journals.lww.com/acsm-essr/Abst…

A thread with figures.

@MilanWBetz

1/6 Satellite cells (muscle stem cells) are essential for muscle repair, regeneration, and the maintenance of skeletal muscle tissue.

The activity of satellite cells is influenced by their interactions with capillaries.

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