A teenager referred with "difficult to control" fits needed non-drug approach for controlling fits
1. 15-year old Rishi had been having fits for the past three months. He used to have jerky movements of hands and legs that lasted several hours and occurred 15-20 times per day.
1a. He was seen by local doctors. MRI brain & EEG were normal.
He was started on anti-epileptic drug (AED). As seizures did not get controlled with single AED, two more drugs were sequentially added. As seizures continued despite giving maximum doses of 3 AEDs, he was referred.
2. Rishi had no past history of fits or febrile seizures in early childhood. There was no family history of epilepsy. He was a bright kid, doing well in studies.
While in OPD, I witnessed one of the episodes of fits, which made me suspect the root cause of fits in Rishi.
3. I obtained more details from parents. Rishi was a bright kid, doing well in studies. After 10th from a reputed international school, he was shifted to a boarding college for coaching for IIT entrance examination.
I requested parents to allow me talk to Rishi in private.
4. While talking to Rishi, I could identify a few possible stressors:
*His parents always compared him with his elder brother, who had already got selected into IIT, & Rishi was made to feel inferior to him.
*He was not able to fully adjust with hostel life & felt home sick.
4a.
*The schedule at boarding college was too tight, with 14 hours of studies and limited time to sleep.
*Rishi was nervous that he may not qualify for IIT, thereby upsetting his parents.
*He was depressed as well as anxious.
Now, the diagnosis was pretty obvious.
5. Got a video EEG recording done that confirmed the diagnosis- non-epileptic attacks (previously called psychogenic seizures).
*I discussed the diagnosis & treatment options with Rishi's parents.
*I counselled them as well as Rishi.
*Psychiatrist & Psychologist were consulted
6. I discontinued all the anti-epileptic drugs. He was started on anti-depressant medication.
At one month review, Rishi looked happy and cheerful. He had remained seizure-free during that period. #MedTwitter#neurotwitter#psychtwitter#epilepsy
7. Take home messages
*Look for stressors in cases of epilepsy, especially if the fits are difficult to control.
*Consider non-epileptic fits if seizure frequency is high or fits are prolonged, or patient remains alert post-seizure
*Careful history and Video EEG aid in diagnosis.
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1. 32-year old Tina was happy & cheerful for 27-28 days every month, however, she feared facing the remaining 3-4 days. She hopelessly wished that those days never ever came, but that was not possible. #medTwitter#neurotwitter
2. Tina used to get severe headaches that occurred only on 3-4 days every month. These days were 1-2 days prior to her menses or during the first two days of menses. She never experienced headache on other days of the month. She had regular periods and had a 2-year old child too.
3. Headaches were severe with a score of 7-8 on visual analog scale (where 10 is the most severe pain, and 0 is absence of pain). Tina had nausea, vomiting and dizziness associated with headache.
Headaches lasted 24-36 hours and they left her completely incapacitated.
Lifelong endurance sport participation on top of a healthy lifestyle is not associated with a more favorable coronary plaque composition.
1. The dose response between long-term endurance exercises such as running or cycling & coronary artery disease (CAD) is a subject of debate
1a. A recent study looked at the association between long-term endurance exercises and prevalence of coronary artery plaques.
2. Three groups of people were selected:
Group 1 had started exercising below age 30,
group 2 started after age 30, and
3rd group maintained healthy lifestyle with minimal exercises. #running#cycling#endurance#HeartAttack
Lack of sleep (<5 h) and excessive sleep (>9 h), both increase the risk of heart attack 1. Insomnia (lack of sleep) is not considered a traditional risk factor for heart attack.
A recent study examined the association between sleep duration and risk of heart attacks. #MedTwitter
2. People with insomnia had 69% higher risk of myocardial infarction (MI, heart attack).
The risk of MI was higher among those who slept <5 hours or <6 hours as compared to those who slept 7-8 hours/night. doi.org/10.1002/clc.23…
3. Excessive #sleep also increased the risk of #heartattack.
People who slept 9 hours or more had a higher risk of heart attack as compared to those who slept 6-8 hours per night.
Sleeping >9 hours and sleeping <5 hours , both increased the risk of heart attack. #CardioTwitter
The prevalence of diabetes and obesity has increased in young adults over the past decade
1. We are witnessing higher numbers of heart attack and stroke in young adults (aged 50 & below). We need to identify the risk factors so that heart attack & stroke can be prevented in them
2. In a recent study, the prevalence of #diabetes increased from 3.0% to 4.1% and #obesity from 32.7% to 40.9% during 2017-20, as compared to 2009-10, among young adults aged 20-44.
3. Other issue of concern is that most of these young individuals are not aware of their cardiovascular risk factors, with 40-50% of them not on any treatment.
Additionally, among those who receive treatment, 30-40% have poor BP or sugar control.
The health-related benefits of #walking does not depend on the time or place of walking
1. Met a marketing professional whose work required travelling on 15-20 days a month, with early morning/late evening flights. He lamented there is no proper time or place to walk. #fitness
2. I suggested that he could walk inside airport terminals (after security checks, while waiting to board flights).
Most people sit, read newspapers, gossip or have coffee/snacks, while waiting to board.
The pictures below show my evening walk at Mumbai airport (T1) last month.
3. Walking would result in similar benefits, irrespective of time or place chosen for walks. One often needs to wait for 30-40 min for boarding, & walking during that time is ideal.
Preferably use stairs instead of escalators.
I remember a similar post of @IamShajanSamuel
Migraine attacks can get triggered by sleeping less as well as oversleeping
1. 29-yr old presented with features of chronic #Migraine for 8 years. Among the triggers for headache, he mentioned lack of sleep as well as oversleeping (>9 hours/night). #MedTwitter#Headache#sleep
2. Lack of sleep is a well-known trigger for migraine attacks.
People with migraine have a higher risk of insomnia and people with insomnia have a higher risk of developing migraine. Those with insomnia also have a higher migraine frequency & severity. …alofheadacheandpain.biomedcentral.com/articles/10.11…
3. Oversleeping too can trigger migraine attacks. This is often referred to as "weekend migraine". The person wakes up in morning (after sleeping >9 hours) with headaches. doi.org/10.3390%2Fijms…