An RCT published in @bmj_latest with two authors from rural India and NO FUNDING. :) Quite impressive. bmj.com/content/342/bm…
My new heroes in medicine - That's the two-people trial team. One day I hope to visit their hospital in rural Maharashtra. For more: ncbi.nlm.nih.gov/pmc/articles/P… 
"he prepared a paper on data of 51 cases of scorpion stings and sent it to an Indian journal. It was rejected for editorial reasons like “English writing not good enough.”
He sent the same paper to Lancet and received a response within 8 days that the report was accepted with minor changes. Thus, his first individual paper titled “Diagnostic cardiac premonitory signs and symptoms of red scorpion sting” was published in The Lancet in 1982."
In Oct 1983, a 8-year-old child was admitted with all the symptoms of severe scorpion envenomation. As he developed pulmonary edema his chances of survival started declining. Dr. Bawaskar asked for his father's consent to use Nitroprusside explaining the dangers of this drug.
He postulated that it would decrease both the preload and afterload on the victim's heart with increased cardiac emptying. With the faith and trust invested by the victim'sfather, he administered Nitroprusside drop by drop monitoring the child minute by minute.
After 4 h, the victim gradually started showing signs of recovery, the blood pressure started rising, pulmonary edema subsided, pulse rate dropped and started oral feeds. 24 h later and almost on the verge of crying, he declared that the boy was saved!
When he was monitoring the child, he received a telegram informing the death of his father. He was in a dilemma to choose between his family obligations and his duty as a doctor. He chose the latter and stayed with the child.
After finding nitroprusside complicated to use in peripheral clinics, he decided to use Prazosin. In 1984, he treated 126 patients with Prazosin; all of them survived. In 1986, in his paper titled “Prazosin in the management of cardiovascular manifestations of scorpion sting”,
which was published in The Lancet he put forward for the first time Prazosin as a physiological antidote for scorpion stings.
The case fatality rate dropped down from 40% to less than 1% with this treatment.
A message from Dr. Bawaskar
“We owe our learning, earning, and satisfaction to our ancestors (scientists) who blessed us with their research. It is our moral duty to repay them by engaging ourselves in, contributing to and publishing the research for the benefit of our future gen
“We owe our learning, earning, and satisfaction to our ancestors (scientists) who blessed us with their research. It is our moral duty to repay them by engaging ourselves in, contributing to and publishing the research for the benefit of our future gen
This can be done only by performing our honest, sincere, and dedicated duty every single day. Never neglect what the patient or his relatives have to say since they are the sole reason of your existence as a doctor.” End of thread. Thanks for reading.
