Discover and read the best of Twitter Threads about #lowcarb

Most recents (23)

1/ Two weeks ago we released our paper on the #LipidEnergyModel (#LEM) along with our video abstract for it. I'm pleased to say it has led to many great connections and expanded discussion.

I'm going to recap on a lot of these in this thread. 🧵 ...

2/ First and foremost, thanks to everyone for their extraordinary support in retweeting our announcement, sharing our paper, and letting researchers know of this model.
3/ As we state many times (including within the video abstract), this model doesn't describe all possible influences on cholesterol levels. For example, other things can impact LDL-C such as M/PUFA-to-saturated fat composition, fiber, genetics, medication, etc.
Read 9 tweets
WOW! >300 retweets in first 24 hours!

1/ Now for a thread from the first author on the #LEM Paper:
👉What it IS
👉What it ISN'T
👉👉and What's NEXT...…

Read on... @realDaveFeldman
2/ What it IS:
We provide the first description of the long-awaited #LEM hypothesis, a model that attempts to explain:

(i) the inverse association between BMI and LDL-C on #lowcarb diets

(ii) the #LMHR phenotype, in which lean people on low carb exhibit very ⬆️LDL-C⬆️HDL-C⬇️TG
3/ These phenomena, presently, have no complete competing explanation:

If effect were purely genetic, the🧬s would need 2explain:
>how macronutrient change can alter, not just LDL-C, but HDL-C+TG as part of a triad
>correlation between BMI and lipid changes

That's a tall order
Read 9 tweets
Stærkt indlæg fra @sebrushworth om insulin ved #type2diabetes. Jeg tror selv, at det skader patienterne mere end det gavne. #Diabetes-lægerne har desværre alt for meget fokus på langtidsblodsukker. #BigPharma har fuld kontrol over diabetes-området.…
Her beskriver @sebrushworth et langt bedre alternativ end insulin ved type2-diabetes: #LOWCARB-diætråd, som med succes blev implementeret i en engelsk #almenpraksis. 46% af patienterne blev helbredt!…
Problemet ved type2-diabetes er so regel at man er for tyk. Man bliver endnu tykkere af insulin. Længere er den egentlig ikke. Men diabeteslægerne i DK gør som @novonordisk og ordinerer Novo's dyre insulin-analoger. 👎…
Read 3 tweets
1/ It's been quite a week on Twitter regarding #lowcarb and LDL

I have been on the fence about weighing in, not wanting to add to the dog pile, but decided 2drop my thoughts in this thread

If u don't have time to READ THE WHOLE THING IN CONEXT, ignore& consider me🪰 on the wall
2/ I'll first address @deirdre_tobias analysis of LDL and all cause mortality. With the caveats that I'm not an epidemiologist &hope to have more insightful questions when time passes and the dust settles, I am not in disagreement w/ the main results: high LDL associated with ACM
3/ That's actually old news, isn't it?Not so say that the analysis doesn't bring something to the table, but on a population level v high LDL levels (will get to low LDL in a minute) are generally undesirable. Thus, all things being =, a conservative gambler would pick low-is LDL
Read 24 tweets
1/ If you want to hear a great discussion on the #LMHRstudy from my colleague,@DrNadolsky (who is most definitely pro-#LDL #Cholesterol lowering), I highly recommend this podcast that just dropped via @Plant_proof.

I'll add just a few quick thoughts...
2/ Firstly, this may be the most I've heard myself talked about in a podcast I wasn't in (😂 weird, but understandable given the context).

But while certainly critical in many respects, I felt both @DrNadolsky and @Plant_proof provided a lot of good context...
3/ @DrNadolsky bring up my oft-repeated phrase, "cautiously optimistic" [in the context of higher LDL/ApoB as a seemingly resulting from metabolic fat-adaption]

Worth repeating that mine is a hypothesis and should be treated as such, hence the "cautious" part of the phrase...
Read 8 tweets
1/ #Keto > #LowCarb

It’s a ironic, my bloodwork looks fine when I’m either keto (less than 25 net carbs) or low carb (25-100 net carbs).

I have a lot more choices when I am low-carb and the food experience is generally more pleasurable with more treats and greater variety…
2/ But in all that time outside of when I’m eating, I just typically feel better. More balanced, better focus, and on top of all of that, I find I simply think about food a lot less. While it’s fun to anticipate a good meal, it can also be an unhelpful distraction.
3/ It’s annoying to have to identify food that is satisfying, but not *too* satisfying. Food I can enjoy but won’t actively overeat. That’s pretty much everything super low carb that isn’t highly refined (I could definitely drink way too much heavy whipping cream “fat shakes”)
Read 4 tweets
(1/n) Some ideas on the planning of a healthy low-carb plant-based diet.


#Vegan #plantbased #lowcarb #ecoatkins

• If you have a serious medical condition &/or take medication, it is necessary to consult your doctor before making changes to your diet.

• Ketogenic diets have been associated with serious side-effects.
(3/n) During the first 7 days on a low-carb diet I suffered: head/muscle aches, hunger, fatigue.

AFAIK alleged ‘cures’ for so-called 'keto flu' haven’t been empirically tested.

I did keep hydrated (but this is *generally speaking* a good idea anyway).
Read 35 tweets
1/ Great new thread by the incomparable, @Lpa_Doc -- covering a number of my favorite topics.

Read his thread and return for my added thoughts...
2/ Vilhjalmur Stefansson is a well discussed explorer among the #LowCarb and (of course) #Carnivore communities.

But even more interestingly, he may have been the first #LeanMassHyperResponder of record*

(* Kinda -- as Sam notes, we didn't advanced lipid panels then)
Read 6 tweets
1/ How much does "Dietary Cholesterol" impact blood cholesterol levels?

This has been making the rounds lately and I have an experiment from 2018 is key to this question 👇

Remember the "White Bread and Processed Meat" experiment?…
2/ If you've followed me a while, you know I believe it isn't the actual ingestion of cholesterol on #LowCarb that has a big impact on serum levels -- it's predominantly the trafficking of fat. (See

But this is actually a very testable distinction...
3/ All we need is an experiment where I consume a lot of (1) low fat food that still (2) has ample amounts of cholesterol.

Thus, the "processed meat" side of the experiment is key if it has a decent amount of cholesterol -- and it does.

For example 9/21/18 I ate the following..
Read 8 tweets
1/ Long running thought exp'nt:

If a drug did many of the same things with one's lipid profile as a #LowCarb diet, particularly decreasing triglycerides while increasing #LDL #Cholesterol:

1) Would it reduce ASCVD risk?
2) And if so, would it be more acceptable than #LowCarb?
2/ If you haven't heard, SGLT2 Inhibitors have recently emerged and have been gaining a lot of popularity. Data thus far shows they typically:

1) Decrease TG levels
2) Increase #LDL #Cholesterol levels
... yet...
3) Reduce risk for cardiovascular disease
3/ Naturally, that has the attention for those of us interested in how triglyceride trafficking and turnover could be relevant to #LDL increasing for what may turn out to be non-pathogenic reasons (kinda my focus ;) )

But wait -- it get's better...
Read 7 tweets
We know this 2013 dietary guideline does not work.
Please do the NHMRC survey in the next 24 hours and make a case for reviewing #Meat #Salt #Cereal #Fat in 2021. @DrPeterBrukner @MueckeDr & I have drafted a letter with options for you - follow the thread.…
A review of the Australian Dietary Guidelines has commenced and we are writing to inform you on how you can participate.
Together, we will be advocating for a review process that is independent, free from conflicts of interest and relevant to all Australians.
It’s vital we call out the influence of commercial interests in the procurement of scientific evidence that impacts our health.
The scoping survey is the first step, and it closes on 3pm AEST, Monday 15 March. It has two key questions that will drive the direction of the review.
Read 27 tweets
I (cynically) don't get excited about much. But I'm so excited about the existence of this new organization that I feel compelled to !!! & ♥️♥️♥️.

OMG check it out & you'll see what I mean!

TOTAL ♥️ GAMECHANGER for #lowcarb & #MetabolicHealth!…
Why is #SMHP a TOTAL GAMECHANGER for the #lowcarb landscape? I go on a bit about it:…
For those of us who read faster than we listen, @BiggestComeback nailed all the high points of why #SMPH offers #hope to those seeking #MetabolicHealth, for themselves or their patients.…
Read 4 tweets
1/ Thread -- Let's Get the Data

Many medical professionals (like my good friend and colleague, @DrNadolsky) feel strongly that #LowCarb-ers may be acting very recklessly by allowing their #LDL #Cholesterol to be much higher than the guidelines allow.…
2/ And this may well be the case.

Certainly if "diet induced" high LDL is the equivalent to genetically high LDL, such as those with #FamilialHypercholesterolemia (FH), then there should be likewise rapidly progressing #atherosclerosis.
3/ "The sine qua non of FH is severe elevation of total and LDL cholesterol levels."…

Often heterozygous FH is considered where LDL is 190 to 500 mg/dL, with homozygous being above 500.
Read 14 tweets

This is keto
This is low-carb
This is real
This is sustainable

I'm going to add as many before/after posts as I can. If you are trapped in hunger, medications, and ill health, you too can get out. #LCHF #keto #lowcarb
Read 88 tweets
Recipe time. Coconut-pecan bars. I got the idea from a @_CynthiaThurlow post about making coconut bars from unsweetened coconut flakes. I’ve been making these for a year now. They are an easy and delicious dessert. 1/6 Photograph of homemade and easy to make coconut and pecan ba
A word of caution for #lowcarb newbies. Avoid this type of food, as I did, for your 1st year. I still must limit how much of this I eat.

You should first become familiar with how well your body handles non-essential foods, like artificial sweeteners, diary, and treats. 2/6
Preheat oven to 350°. Pour 21 oz of unsweetened coconut flakes. Optional: 2 tbs of baking cocoa. Dump into a processor and let it run for 8 - 10 minutes. Wait for the flakes to become liquid-like. The processing also warms the slurry, which is helpful for the next step. 3/6 Photograph of our trusty old food processor processing the u
Read 7 tweets
If you want to avoid an orthopedic surgeon at some point in your life, and don’t want lengthy, complicated advice, I have two simple principles:

1. Employ risk mitigation (this is the obvious one) : Wear seatbelts, dont text and drive, etc. (the other is not so obvious)
2. Change your diet to a #lowcarb diet for life. Why? Simple. It addresses the #rootcause or associations in most chronic diseases (obesity, high blood pressure, type 2 diabetes, coronary artery disease, many cancers, benign prostatic hyperplasia, polycystic ovarian syndrome,...
...Non-alcoholic fatty liver disease, dementia, etc) INCLUDING that which leads to joint pain/inflammation and tendon tears. Through a process called glycation, sugars get deposited on soft tissues, leading to Advanced Glycation End-products (AGEs). These AGEs...
Read 10 tweets
I wanted to collect my thoughts on the study released earlier in the week by @KevinH_PhD. It turned into this blog-sized thread.

The study compared a high-carb, plant-based diet to a low-carb, omnivorous diet in a 4 wk. cross-over study.

The results created quite a stir.

Participants were randomly assigned to a plant-based diet or low-carb diet for two weeks. They then switched to the other diet for the following two weeks.

Both groups lost weight but participants on the plant-based diet ate less and lost more fat, despite higher insulin.

This triggered some to question whether the carb-insulin model was dead. CICO enthusiasts took a few victory laps, bashing low-carbers as foolishly fixated on carbs and beyond reason.

Read 13 tweets
For all those who argue as nauseum about #lowcarb !! I'm a doctor and I'm not an idiot to tell people to stay off medicines and focus on inner immunity and health. All my life I struggled with a hypocaloric high carb diet. That's why I feel deeply about this whole topic. #health
I was a plump child and was always told to eat less and exercise more. I was always hungry. I grew up to a fat teen with a terrible body image. It drives me up the wall to see people unnecessarily arguing about the so called balanced diet. I tried all gimmicks : Alas
Thank God that I came across #IntermittentFasting and #lowcarb. It's never about #weight. It's about #Health. #weightloss and a #positiveattitude is the by product.
Thank you to all those who have been a part. I'm 3 years menopausal now. And pretty much fit for my age. #fit
Read 6 tweets
1/ #ListenThread -

My guest appearance on #SigmaNutritionRadio just dropped where I have a very friendly #debate with @NutritionDanny and Alan Flanagan on #LDL #Cholesterol, #ApoB, #Atherosclerosis, #AllCauseMortality & much, much more!
2/ I did this podcast semi-sleep deprived and between interviews for #TheCCDoc. But I know my main hopes going in were to emphasize:

(1) Why I favor the "Lipid profile-centric" model over the "Lipoprotein-centric" model.
(2) How this is relevant to "the triad" ⬆️LDL⬆️HDL⬇️TG

(3) Why this triad is of particular interest to all of us as it relates to not just cardiovascular disease, but in particular -- all cause mortality (ACM)

I honestly couldn't remember how well I did in getting these core points across, thus relistening now...
Read 64 tweets
In five days we begin filming #TheCCDoc -- a documentary on #Lipids, #HeartDisease, and the phenomenon of higher #LDL #Cholesterol observed in many following the #keto/#lchf lifestyle.

This will either be a single feature length documentary (90-120m) or a series of topic episodes (40-55m each)

I'll be interviewing experts across the opinion spectrum. Pro lipid hypothesis, moderate, skeptic, liberal on statins vs conservative, etc.

We'll explore:
1. History of cholesterol discovery
2. The #LowCarb movement and high "diet induced" #LDL
3. The science and data of risk: intervention, genetic, and observational
4. The two Triads, atherogenic dyslipidemia and ⬆️LDL+⬆️HDL+⬇️Triglycerides

Read 9 tweets
@lowcarbGP @grahamsphillips @LowCarbProgram @SamFeltham @DocRunner1 @ProfTimNoakes @FructoseNo @RaceToTheStones @LowCarbSurge @longevity_pro @drtroystapleton @cadiulus @CampbellMurdoch @JeffryGerberMD @FatEmperor @SBakerMD @russwinn66 Just for you @lowcarbGP and for science: after 18h fast I took the #bananachallenge 😳

1pm Glu from 3.7 to 5.6 over 60min and made me hungry+++

Second ‘hump’ after 2pm was the other half #couldntresist
@lowcarbGP @grahamsphillips @LowCarbProgram @SamFeltham @DocRunner1 @ProfTimNoakes @FructoseNo @RaceToTheStones @LowCarbSurge @longevity_pro @drtroystapleton @cadiulus @CampbellMurdoch @JeffryGerberMD @FatEmperor @SBakerMD @russwinn66 And in further exciting news:

50:50 mix of heavy cream with @Breyers #lowcarb ice-cream is both delish and #flatlineish

I’m not one for treats (and don’t wish to re-awaken my sugar-cravings) but this is good to know #cgm
@lowcarbGP @grahamsphillips @LowCarbProgram @SamFeltham @DocRunner1 @ProfTimNoakes @FructoseNo @RaceToTheStones @LowCarbSurge @longevity_pro @drtroystapleton @cadiulus @CampbellMurdoch @JeffryGerberMD @FatEmperor @SBakerMD @russwinn66 And after tomorrow’s #runandfast I shall be testing this trusted #runningfuel:
22g CHO as maltodextrin/60ml
Recommended dose 1-3x per hour
I’d need ?20x for 100k (that’s 1200ml to carry/digest) 😳
Read 18 tweets
Good Morning! Day 2 of #LowCarbSeattle will start soon. Today I will have individual threads for the presentations. Speakers today are @DrAseemMalhotra , @tednaiman , @obesityresolved , @LDLSkeptic , and @DaveKeto . Totally enjoying the conference. Thank you @lowcarbusa !
Today's talks: @DrAseemMalhotra Public Health Advocacy; @TedNaiman Macros & Metab; @obesityresolved Obesity Understood, Obesity Resolved; @LDLSkeptic LDL & LCHF; @DaveKeto A Deep Dive into Cholesterol & Risk.
@DrAseemMalhotra @tednaiman @ObesityResolved @LDLSkeptic @DaveKeto First up .@DrAseemMalhotra is having to present via Skype or similar. A bit of connectivity issues, but better now.

Obesity on the rise in UK. Ease of access to ultra processed foods feed problem. Hospitals allow junk food on their campus.
Read 48 tweets
NEW THREAD on #LCHF-raud & #KetoDiet.
The following article I wrote has references to over 1200 studies on nutrition, including Randomized Control Trials. 👉…
5 Reasons I Don't Recommend a Keto Diet by Dr. Michelle McMacken @Veg_MD 👉…
Gary Taubes, author of several books and articles on low carb high fat #LCHF-raud diet (fad), FINALLY concedes that saturated fats are the enemy in this BMJ article: 👉…
Read 45 tweets

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