Discover and read the best of Twitter Threads about #Mycophenolate
Most recents (2)
Good Morning #MedTwitter #neurotwitter #MedEd #Neurotwt #Neuroresidents #NeuroOphthalmology #Neuroimmunology #twittorial. Let's have a quick review on #OpticNeuritis and #NMO - Grab a #coffee and let's Start!
1/ Classic #opticneuritis is characterized by a sub-acute loss of vision in one Eye, with central #scotoma, pain on #eyemovement, positive #RAPD
- Fundus exam is usually normal
- Age range 15-45 years
- Fundus exam is usually normal
- Age range 15-45 years
2/Talking about #MOGAntibodies:
- More frequent in #pediatric population, Associated with #ADEM
- #MOG IgG serum titers depend on disease activity and is mainly from extrathecal origin, enters #CNS from systemic circulation and reaches CSF through passive diffusion or broken #BBB
- More frequent in #pediatric population, Associated with #ADEM
- #MOG IgG serum titers depend on disease activity and is mainly from extrathecal origin, enters #CNS from systemic circulation and reaches CSF through passive diffusion or broken #BBB
1/
Here's another #immunosuppression #tweetorial. This time, a focus on mycophenolic acid (MPA). #MMF #Mycophenolate
The main mechanism of action of MPA is inhibition of which of the following:
Here's another #immunosuppression #tweetorial. This time, a focus on mycophenolic acid (MPA). #MMF #Mycophenolate
The main mechanism of action of MPA is inhibition of which of the following:
2/ Let's meet the players. Mycophenolate mofetil (MMF, left) is a prodrug of MPA while mycophenolate sodium (MPS, right) is an enteric-coated salt of MPA.
MMF administration releases MPA in the stomach, while mycophenolate sodium (MPS) releases it in the small intestine.
MMF administration releases MPA in the stomach, while mycophenolate sodium (MPS) releases it in the small intestine.
3/ MPA is often referred to as an "anti-metabolite", which means a substance that interrupts a metabolic process within cells.
The process that MPA interrupts here: PURINE SYNTHESIS
The process that MPA interrupts here: PURINE SYNTHESIS
