, 4 tweets, 1 min read Read on Twitter
Genotype–phenotype associations in children with copy number variants associated with high neuropsychiatric risk in the UK (IMAGINE-ID) thelancet.com/journals/lanps…
Copy number variants (recurrent deletions or duplications of specific chromosomal segments) associated with risk of neurodevelopmental disorders affect multiple systems + don't have strongly distinct clinical profiles
These means focusing too much on the specific genes in each CNV may be a mistake - the symptoms are not likely linked to their biochemical activities in any direct or specific way
Instead, neurodevelopmental disorders, like autism, ADHD, anxiety disorder, may reflect general ways the brain reacts as a dynamic, self-organising system to very diverse genetic insults
Missing some Tweet in this thread?
You can try to force a refresh.

Like this thread? Get email updates or save it to PDF!

Subscribe to Kevin Mitchell
Profile picture

Get real-time email alerts when new unrolls are available from this author!

This content may be removed anytime!

Twitter may remove this content at anytime, convert it as a PDF, save and print for later use!

Try unrolling a thread yourself!

how to unroll video

1) Follow Thread Reader App on Twitter so you can easily mention us!

2) Go to a Twitter thread (series of Tweets by the same owner) and mention us with a keyword "unroll" @threadreaderapp unroll

You can practice here first or read more on our help page!

Follow Us on Twitter!

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just three indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3.00/month or $30.00/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!