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, 9 tweets, 6 min read
🔵Janet Englund, Fred Hutch, US up next on #flu and other respiratory viruses (RespVs)
🔵slow cell/antigen based testing to PCR-based testing has vastly improved speed - notsomuch in surveillance setting
🔵 #Flu viruses not the only game in town

#ais2019bris
🔵What is "important" among RespVs
🔵34% of US kids in childcare (24% in AUS)
🔵Seattle #flu study (2018-2019)
🔵identify importation, within-host evolution, compare clinical characteristics & improve understanding in certain populations
#ais2019bris
🔵So, in childcare...
🔵things are easier now compared to decades past (e.g. Paul Glezen, only detect 31% of infections)
🔵then, newer molecular methods found 4.2 symptomatic virus episodes/child
🔵now, 103 enrolled , half the embers of each room
🔵#AIS2019Bris
🔵#flu was not eh highest virus found, but responsible for a lot of missing childcare and parental work-often stayed home
🔵mean of 3.9 sample/flu season
🔵#rhinovirus the most commonly found (not commonly febrile - so still went to childcare!)

#AIS2019Bris
🔵the big3 were there - Respiratory syncytial virus (#RSV), human metapneumovirus (#MPV) and #Flu
🔵even the non-walking little types spread viruses well
🔵#flu % #RSV the biggest causes of childcare days & work lost
#AIS2019Bris
🔵 ~95% (!) were vaccinated (attenuated, quad)
🔵 A/H3N2 (dominated) component wasn't greatly effective during this study period's #flu season (2018-19)
🔵 RSV next. RSV usually precedes #flu, not this time
#AIS2019Bris
🔵this study highlighted that over decades, many of the same RespV patterns remain in place
🔵in a 2006-8 study, PCR-supported epidemiology identified very fast spread, lots of coinfections - in all the kids, all the time (NOT just #rhinovirus, [RV])
#AIS2019Bris
🔵2 or 3 viruses on day 1, a week late, 1 virus retained, and two NEW viruses! - sick all the time
🔵human bocavirus (HBoV) a big deal as well; not a virus without a disease. a primary pathogen.
🔵SO MANY different genotypes of RV - couldn't track origin
#AIS2019Bris
🔵QUESTIONS
🔵options for prevention? Really don't know
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Related hashtags

#flu #AIS2019Bris #rhinovirus #RSV #MPV

More from @MackayIM see all

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ɪᴀɴ ᴍ ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🇦🇺
@MackayIM
😷Lab-confirmed #Flu in #Australia to 21SEPT2019
⚪ pink line=positives for 2019, other colours=other years
🤧+3,143 over last *2* days
🤧283,742 cases for 2019
😷Lab-confirmed #Flu numbers
🤧Difference in totals, between reporting days, #Australia
🤧decline in positives slowly continues from mid-July peak
⚪ graph is a guide only. Each total may include NNDSS numbers that were added to previous as well as current days
😷 Rates and States, #Flu. New South Wales (NSW) remains the hottest spot overall
🤧 South Australia's (SA) early surge retains it the jurisdiction with the highest rate of cases per 100,000 population, but NSW closing in
Read 20 tweets
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ɪᴀɴ ᴍ ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🧬🥼🦟
@MackayIM
Lab confirmed #Flu cases in #Queensland for week to 19MAY2019 (Wk20)...
😷 11,144 year2date (+735 cf last week)
🤧 FluA: +641 (86% of Flu detected this week; +296 cf last week)
▶️ 5 H1N1
▶️ 14 H3N2
▶️ 515 not subtyped
🤧 FluB: +107 (14%; +41)
▶️ 2 VICT lineage
▶️ 0 YAMA
😷 Week 20
🤧10.5% of samples tested at public labs are positive for #Flu

Source: Epi and Research Unit, CDB, Dept Heath, #Queensland Healthhttps://www.health.qld.gov.au/clinical-practice/guidelines-procedures/diseases-infection/surveillance/reports/flu
😷 FluA dominates but FluB cases have been at 14% or above for past 4 weeks above up this week
🤧FluA 74:26 H3N2:H1N1
🤧FluB mainly Victoria lineage (FYI: last FluB-dominated year, 2015, was led by strains of the Yamagata lineage)
Read 5 tweets
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ɪᴀɴ ᴍ ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🧬🥼🦟
@MackayIM
#Ebola 01APR2019...
💊 1092 prob+conf total cases (+3 compared to y'days report)
🔬 291 suspected (+111)
🔬 66 probable (+0)
🔬 1026 confirmed (+3; +1 Katwa, +1 Butembo, +1 Mandima)

Source: us13.campaign-archive.com/?u=89e5755d2cc…
💊 683 fatal #Ebola virus disease cases (+4)
🔬+1 Katwa health zone (HZ; deaths in community)
🔬+3 Butembo HZ (deaths in a treatment centre)
🔬 92 cases in past 10 days; 48 in past 5
🔬 2 days with only single digit cases
🔬When suspected cases jump, confirmed sometimes follow
💊 93,996 vaccinated (+307 since y'day's report)
Read 10 tweets

Related threads

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Raechel Soicher
@rnsoicher
Next up for me at #SIRC2019 - Implementation Outcomes and Measures breakout session.
1st up: Aaron Tierney speaking on his work from Stanford - Advancing evidence synthesis from effectiveness to implementation - recs for integrating implementation measures into evidence review. #SIRC2019
Project trying to - (1) enhance usefulness of evidence synthesis projects and (2) start conversation about standardizing reporting of implementation factors in future intervenion & evidence synthesis projects. #SIRC2019
Read 50 tweets
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Allison Rand
@allisonrandom
Next up: “The Times They Are A’Changin:” Information LIteracy Instruction, Faculty Ownership, and Student Success.” Very relevant to my job — is it possible for me, the only instruction librarian, to reach everyone effectively? #loex2019
Students know their discipline but they don’t know how to participate in their discipline. This is something I have conversations about a lot — how do we arm the students for the workforce? #loex2019
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Read 11 tweets
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sflc.in
@SFLCin
On December 20, 2018, the Ministry of Home Affairs issued a statutory order authorizing 10 agencies to intercept, monitor and decrypt communications of citizens. The order may be read, here - bit.ly/2rYlx0z #Surveillance
The agencies authorized by MHA include - Intelligence Bureau, National Investigating Agency and Commissioner of Police, Delhi. The order was issued under existing powers given to the MHA as per Section 69 of the IT Act, 2000 and corresponding rules. #Surveillance
Section 69 empowers the govt. to issue directions for surveillance of communications. The corresponding rules empower the MHA to notify other govt. agencies which can perform such surveillance. Thus, these agencies have been notified under existing rules under the IT Act.
Read 20 tweets
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Scott Gottlieb, M.D.
@SGottliebFDA
It’s the start of flu season – time to protect yourself and your family by getting vaccinated! In today’s #FDA #SUNDAYTWEETORIAL I’m going to talk about #FDA’s role in ensuring the safety, effectiveness, and availability of the 2019 influenza vaccines. #VaccinesWork #FightFlu
I know there are questions about the effectiveness and benefits of the flu vaccine given the severity of last year’s flu season, so I want to update you on what we’ve learned, the effectiveness of this year’s vaccine and why vaccination is important go.usa.gov/xPWhS.
We've made important modifications to this year's #Flu vaccine to improve its effectiveness; changing two of the strains (for the H3N2 and Influenza B components) to better reflect the influenza strains that we believe are most likely to circulate this winter. More on this later.
Read 22 tweets
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Catherine Walsh
@gurriersread
#next, I need your #help, and I mean all of you #please, regardless of party-politics, ideological differences, geo-location, can I have your <3 engaged to help a family, friends, a local community & a student community in their #search for a #MissingPerson #missing since Nov.2nd
2/" #StephenCullinan (25), the son of North #Tipperary #IFA Chair, Tim #Cullinan, hasn’t been seen since November 2 when he left his home in Castletroy, County #Limerick and made his way to #Dublin. "
independent.ie/irish-news/new…
3/"His worried relatives believe he may have made his way to another major Irish city, even as far as #Belfast. The vulnerable young man is without his medication." " He could be in #Galway. We’re grasping at straws."
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Tiago Forte
@fortelabs
1/ I'm increasingly convinced that THE most important thing in productivity is to end every cycle with a clear milestone or deliverable
2/ Both "deep work" (large batch) and "multitasking" (small batch) miss the point in this regard
3/ The absolute size of your work batches doesn't matter, and a wide range of sizes is probably best
Read 29 tweets

Trending hashtags

#WhereIsPickle #DAPeoplesVoice #agile #WaterBear #StoatsAsMeasurement #2018MM #AmericasBestIdea #Galway #2018MMM #Carnage #RuhRoh #UL #kzoo2019 #viral #bangbangconwest #SneakyNotACat #2019MM #TeamManatee #BASED #2019MMM #TwistTheKnife #whew #StephenCullinan #YumYum #gdc18
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