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There are >13 active therapies in clinical trials to treat the new coronavirus - and they map to at least half a dozen mechanisms, intervening at three different steps in the viral cycle or manipulating different aspects of the host immune response. biocentury.com/article/304409
2) As of Feb. 7, 13 clinical trials to treat 2019-nCoV acute respiratory disease have been registered on ClinicalTrials.gov, + another 19 trials have been listed on the Chinese Clinical Trial Register. Trial registries are important to prevent hiding negative results later.
3) The most common MOAs are inhibitors of viral proteases or RNA synthesis. Gilead has the largest number of therapies in testing for the virus, at three. It also has the only non-approved therapy in the clinic: the nucleotide analog remdesivir.
4) On Tuesday, a draft report of WHO’s R&D Blueprint Clinical Trials expert group named Gilead’s remdesivir the most promising 2019-nCoV candidate. (FYI: I have no financial stake in nor work for any pharma company. Just citing WHO report) biocentury.com/article/304374
5) 📌You can see the latest 18 active trials (as of Feb 8th at 11pm EST) on the Clinicaltrials registry site... 8 are currently already actively recruiting. Most are in China. Save this page and refresh to monitor status of all trials! It’s run by US govt. clinicaltrials.gov/ct2/results?co…
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