Allegations of “strong evidence” for mandatory cloth masks worn by healthy ppl in public by @patrickbrownont @BonnieCrombie are absolutely false. Their decision is political. It is NOT based on known published scientific evidence on #COVID19. Here is recent Lancet systemic review
2/Even in remarks made by Peel Public Health Officer Dr Loh, he stated evidence not definitive. I must remind residents that the same Officer prev told Peel frontline HCWs w/COVID19 to return to work w/out 14d self-isolation d/t politics, not evidence. This is again more politics
3/ These politicians even admit they are acting based on public opinion. Public Health policy must NEVER be politicized—esp NEVER any mandatory actions. This is not science. Peel PH’s own study recently found 87% of #COVID19 cases are in healthcare setting
4/ @patrickbrownont claims it’s “data driven”—explicitly states he asked public if this is necessary & ppl “believe” it is right thing to do. Dr Loh @regionofpeel states they’re doing “public surveys”. @BonnieCrombie states “residents asking for it”. This is POLITICS. Not science

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More from @dockaurG

4 Sep
1/ US & UK media finally reporting what we've known for months from published peer-reviewed research by leading scientists🌎: pre-existing cross-protective Tcell immunity & strong Tcell responses bode well for long-term #SARSCoV2 immunity, and #HerdImmunity may already be at hand
2/ US: "We may be closer to #HerdImmunity than previously thought. Are we fearing a ‘second wave’ which our immune systems already have well in hand? People show immunological response to #SARSCoV2 in their Tcells.. without necessarily showing antibodies."
spectator.us/closer-herd-im…
3/ "#HerdImmunity may be closer than thought—UK scientists say immunity likely far higher than what govt antibody tests shows b/c it doesn't account for Tcells. Top immunologists said infection-fighting Tcells are more durable/long-lasting than antibodies"
dailymail.co.uk/news/article-8…
Read 4 tweets
6 Jul
Pls read #SARSCoV2 immunology🧵& subthreads for what media & “experts” are not telling you

Facts
-we have some pre-existing cross-protective immunity
-basing herd immunity only on antibodies omits strong Tcell immunity
-vaccine candidates not effective b/c don’t elicit IgA prodn
2/ Last week, researchers in Sweden and Germany also found strong T-cell responses to #SARSCoV2 which bode well for long-term immunity & found pre-existing cross-protective immunity: findings are consistent with the original US Cell study published in May.
3/ We now have three independent #SARSCoV2 studies, from teams of scientists in three different countries, all concluding the same thing:

#COVID19 Herd Immunity Is Much Closer Than Antibody Tests Suggest”
reason.com/2020/07/01/cov…
Read 13 tweets
5 Jul
53+ published #HCQ studies in #COVID19—strong efficacy as prophylaxis & as treatment in early COVID19. HCQ is std of care in COVID19 tx protocols for many countries🌎 w/lowest fatality rates. Govts allowing ppl to die by blocking access to life-saving meds
c19study.com
2/#HCQ activates host anti-viral innate immunity—strong efficacy as prophylaxis & as treatment in EARLY #COVID19 esp w/in 5d of symptoms. Now we know why

CDC: >88% don't yield replication-competent #SARSCoV2 virus after 10d & viral shedding drops after 6d
cdc.gov/coronavirus/20…
3/ Recent pre-print systematic review & meta-analysis on "#SARSCoV2 viral load dynamics, duration of viral shedding & infectiousness" found:
"SARSCoV2 titres detectable in first week of illness with early peak observed at symptom onset to day 5 of illness"
medrxiv.org/content/10.110…
Read 5 tweets
4 Jun
Based on published #HCQ studies & case-controlled clinical trials, HCQ has significant efficacy in early treatment of #COVID19: PRE-exposure prophylaxis & early POST-exposure treatment. Recent NEJM RCT focused on NEITHER of these 2 key groups but rather: POST-exposure prophylaxis
2/ Here’s link to NEJM #HCQ RCT published today on POST-exposure prophylaxis given up to 4d AFTER exposure. Disturbing that science was again politically sensationalized by media before study was even published w/quotes from MD with #Gilead #BigPharma COI
nejm.org/doi/full/10.10…
3/ “The results reported by Boulware et al. are more provocative than definitive, suggesting the potential prevention benefit(s) of #Hydroxychloroquine remain to be determined,” concluded Dr. Myron Cohen MD in NEJM editorial re recent NEJM HCQ #COVID19 RCT
nejm.org/doi/full/10.10…
Read 4 tweets
26 May
Imp Thread: public health fallacy to claim popn #SARSCoV2 IgG serology tests capture all pts recovered from #COVID19: grossly UNDERestimates % popn that was asymptomatic & recovered. Key arms of immune response to #SARSCoV2: humoral with antibodies & cell-mediated with T-cells
2/ Current public health method to estimate population immunity to #SARSCoV2 from recovered asymptomatic #COVID19 ppl uses serology tests to detect IgG antibodies: this only captures humoral immunity. Currently no widely available testing kit for T-cell immunity to #SARSCoV2
3/ Pts mount strong T-cell immune responses to #coronaviruses. Published Cell research & studies on recovered #COVID19 pts w/immunodeficiency disorders w/inability to mount B-cell responses to #SARSCoV2 reveal B-cell antibody responses not strictly required to overcome COVID-19
Read 6 tweets
16 May
Recent @CellCellPress #COVID19 study on #immunity helps explain why these 2pts with X-linked agammaglobulinemia (genetic immunodeficiency where pts have complete abscence of Bcells: inability to produce antibodies) developed COVID19 pneumonia—but RECOVERED
onlinelibrary.wiley.com/doi/abs/10.111…
2/In another recently published case #COVID19 study in @AnnalsAllergy—pt with another genetic immunodeficiency (common variable immunodeficiency on monthly IVIG w/stable bronchiectasis) had #COVID19 but fully recovered after ICU care despite increased risk
annallergy.org/article/S1081-…
3/ Of note, CVID pt with #COVID19 also had breast cancer in remission on tamoxifen OD, hypothyroidism & Sjögren’s on #hydroxychloroquine 200mg BID. She presented to ER on D7 of symptoms. Her home dose of hydroxychloroquine was incr to TID w/IVIG. No azithromycin d/t known allergy
Read 4 tweets

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