This is why research & #scicomm now about virus transmission is so critical

"We’re going to have to be in a world that is more thoughtful about protecting ourselves from respiratory infection than we have ever had to be before.” Dr. Bloom, @HarvardChanSPH
pri.org/file/2021-02-0…
(Starting at 2:31): “This is a global infection. A mutant or variant anywhere is a threat everywhere. And so we can’t be complacent and say because hopefully we start to do well by summertime in the US we will not be invaded by a new variant. So we really have to ..."
".. continue public health measures: wearing masks, reducing opportunities for spread, and being very careful, because even with vaccines, they’re not perfect, no vaccine has ever been perfect. ..."
"..And we’re going to have to be in a world that is more thoughtful about protecting ourselves from respiratory infection than we have ever had to do before.”
"The best way to prevent the emergence of mutants is to reduce the amount of circulating viruses that hang around and can make mutants. So the lower the number of viruses in the community, the lower the number of viruses in any individual through..."
".. through facemasks, through distancing, through avoiding crowded places, through washing of hands, the lower that number is, the lower the probability a mutant will emerge. That’s the simplest of all facts. ..." (Dr. Bloom)

Via @MarcoWerman @TheWorld
pri.org/file/2021-02-0…
"..The ideal of a vaccine is simply to reduce the number of infectious viruses as a way of reducing the number also that can make mutants.”

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More from @HuffmanLabDU

11 Feb
1/ Interesting paper showing high efficacy of portable HEPA #filtration to reduce aerosol concentration in a high school classroom during use.

By very experienced German aerosol group Curtius et al.; via @ASTJournal.

With short🧵on room air filtration.
doi.org/10.1080/027868…
2/ "In times when classes were conducted with windows and door closed, the aerosol concentration was reduced by more than 90% within less than 30 min. when running the purifiers (air exchange rate 5.5 ACH). The reduction was homogeneous throughout the room ..."
[note log y-scale] Image
3/ Figure 3: Highly reproducible reduction in aerosol particle concentration [uCPC] in a closed classroom without air purifiers (blue line) and with 3 or 4 air purifiers operating at speed 3 or 4 (max). Image
Read 15 tweets
10 Feb
1/ You've surely seen constant recent messaging & articles imploring you to improve quality of both #mask fit & filtration, in part b/c of worrying COVID variants.

Good news that the #CDC is catching up w/ those messaging efforts w/ updated guidance today.

Short 🧵 of links.
2/ Another good summary thread of the CDC changes; by @AbraarKaran, who has been among ardent supporters lobbying hard for #bettermasks:
3/ One good example summarizing the new #CDC guidance changes on masks, w/ helpful infographics, interviews, and short video w/ CDC chief Dr. Walensky.

By @bylenasun & @FenitN
washingtonpost.com/health/2021/02…
Read 5 tweets
5 Feb
1/ In context of extra precautions against new COVID variants, some new questions pop up about #masks.

Article by @cwarzel @zeynep asks/answers some good questions to start. Other thoughts in a 🧵, e.g. N95s, fit (Tw7+ ⬇️), when to replace (Tw25 ⬇️), etc.
nytimes.com/2021/01/29/opi…
2/ Countless recent articles w/ interviews from relevant experts imploring people to still take mask-wearing & overall airborne COVID health seriously.

One of many, here by @skbaer w/ broad contribution. (Tw33 below has link to a compilation of more).
buzzfeednews.com/article/skbaer…
3/ Many good arguments recently towards motivating broader use of #bettermasks, i.e. #N95s. So if not using already, consider.

See e.g. this editorial by @j_g_allen: washingtonpost.com/opinions/2021/…

Or this opinion-piece by a group of excellent scientists:
Read 33 tweets
3 Feb
1/ Public admission by @mvankerkhove of #WHO that COVID transmission "goes through the air" is a *huge* turn-around from strong, incorrect statements to the contrary.

Strikes me as significant, even if subtle & played off as "we knew all along."

Full vid
2/ Earlier messages #WHO put out were blatantly wrong & dangerous ⬇️.

Many scientists globally have been working tirelessly to pressure @WHO to retract dangerously misleading statements like this & adequately educate that #COVIDisAirborne.
3/ Again, messaging efforts by WHO are critical b/c of their exposure & reach. By openly saying COVID isn't in the air & having press conferences w/o masks, have been undermining efforts to #MaskUp & prevent spread.

Baby steps today, still work to do!
Read 7 tweets
3 Feb
Updated preprint on COVID risk modeled from respiratory aerosol data

Notice ⬇️:
- No "safe" distance indoors, b/c aerosols travel
- Masks & ventilation increase safe time, but still risk

Graphs: below each line = safer

HT @linseymarr & @kprather88 (1/x)
medrxiv.org/content/10.110…
2/ Study used the #WellsRiley model to estimate COVID risk from respiratory aerosols in a variety of scenarios, using particle size distribution data from previous studies.

Quanta: Statistical measure of avg infection probability; bigger value = easier to infect [~1 - e^-quanta]
3/ Bazant & Bush study supports broad consensus of observation & preventative steps:

✅No single action sufficient for COVID prevention
✅Steps compound reduction in risk, but never to zero
✅All important: distance, masks, reduced time, incr. ventilation
medrxiv.org/content/10.110…
Read 6 tweets
1 Feb
Imp. perspective to remember.

"Excessive attention on making surfaces pristine takes up limited time & resources that would be better spent on ventilation or the decontamination of the air that people breathe": @linseymarr

By @dyanilewis HT @rye_b (1/x)
nature.com/articles/d4158…
2/ A few other key quotes/reminders:
“It’s become clear that transmission by inhalation of aerosols — the microscopic droplets — is an important if not dominant mode of transmission,” says Prof. @linseymarr , who studies airborne disease transmission.
3/
“You have to make up some really convoluted scenarios in order to explain superspreading events w/ contam. surfaces”
“If we’ve already paid attention to the air & we have some extra time resources, then yes, wiping down those high-touch surfaces could be helpful”: @linseymarr
Read 5 tweets

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