Why did you have Placebo effect?
Becoz of another cognitive bias
Survivorship bias
"We tend to focus on thos things that survived a process and overlook ones that failed"
This happens when you see/read many testimonials on Siddha working in others who also suffer from biases 2/
These two biases create another bias.
Blind Spot bias
We dont think we have bias, but see it in others more than ourselves
So when science tells you that there is no evidence to demonstrate any benefit of Siddha in treatment of Covid, you consider scientists as biased 3/
But are scientists biased?
Yes, they can be.
So how do they correct for it?
Becoz science is not biased.
"Science is an inherently probabilistic endeavor.
It shows us what is most likely true given the current evidence, not what absolutely is true." 4/
So what does science say about Siddha?
That it is pseudoscience
Why pseudoscience?
Becoz it is unreasonable
Siddha does not follow a scientitic method, but culture
Relies on belief tat earth, water, fire, air, sky – are in food, "humours" of human body
This is illogical 5/
Now coming back to Siddha improving Covid.
It most likely did not. In mild covid, patients improve without even modern medicine prescriptions and only symptoms care
We do not have quality evidence through rigorous clinical studies that Siddha does anything to any disease
6/
So promoting Siddha for Covid or any other disease per say, is currently not in the best interest of public health
One must show refrain
Here is an infographic on 'cognitive biases'
India's terrible and nonsense craze about health benefits of cow urine
What are claims?
Kills germs
Protects heart and brain
Protects organs in general
Detoxifies body
Using in eye will improve eye sight
Older the urine, better benefits (?like honey)
Avoid plastic container
1/
Is cow urine good antibiotic, antifungal or antiviral?
This review on antimicrobial function of cow urine is rich in studies conducted on cells and tissue cultures. ncbi.nlm.nih.gov/pmc/articles/P…
They have reviewed extensively on in-vitro studies between diff types of cow breeds...
2/
...when urine from every cow is same.
Gujarati Geer cow doesnt produce urine quality different from Karnataka Amrit Mahal cow
But yes, there were studies comparing different breeds as per review which is inherently foolishness
2 #2deoxy2glucose is basically glucose molecule in wich 2-hydroxyl group replaced by hydrogen, so that it cannot undergo further glycolysis (which is the metabolic pathway that converts glucose to pyruvate and a hydrogen ion, during which, the free energy released in process...
3...is used to form high-energy molecules such as ATP or NADH that helps in various cell functions). So basically, by using 2DG, the normal glycolysis doesnt happen and cell functions get blocked. This is the reason it is used for cancers
Cancer cells depend heavily on glucose...
Y #Ivermectin doesn't work
1 #ivermectin craze 4 #COVID19India started in South-America, spread like wildfire to USA/Europe. Heavily criticized in countries upholding #science, didnt find place in guidelines. BUT, nw it reached #India, into minds/hearts of doctors not due to...
2...the #science, but bcoz National institutions such as @aiims_newdelhi/ certain govts @goacm endorse it - without getting into the science of it. Nw, #ivermectin is slowly bcoming nationalist boy scout of #medicine in #India, wrngly endorsed by naïve students/senior professors.
3 Ivermectin is broad-spectrum antiparasitic approved by @US_FDA, proved to be safe at dose of ≤200 µg/kg. In a 60 kg man, the max conventional dose in 12 mg.
Caly et al (not Baba Ramdev) bit.ly/3vO9cuK identified in-vitro (cell study) anti-#SARSCoV2 ivermectin activity
1
I challenge ur narrative tat alternative medicine works
It doesnt/#neem studies tat u keep quoting, are NOT peer-reviewed, NOT published/has been collecting dust in preprint server since Apr 2020
Tis makes ur argument invalid
But #science is kind, so lets discus #MedTwitter
2 indiarxiv.org/pyqx4/ This is UR molecular docking study u uploaded to preprint. Y was this never published? Bcoz this is highly flawed from methods to results to conclusions. Molecular docking was blind - hence ligand optimization is not accurate... #ayush
3
...and grid coordinates wer computer generated. Hw did u correct for tis? U cud hav used predicted binding sites 2 improve accuracy/efficiency ncbi.nlm.nih.gov/pmc/articles/P…
Predicted binding sites 4 #SARSCoV2 is widely published/ use of grid-based docking wud be better...